| Full name: PARP1 binding protein | Alias Symbol: FLJ20641|PARI | ||
| Type: protein-coding gene | Cytoband: 12q23.2 | ||
| Entrez ID: 55010 | HGNC ID: HGNC:26074 | Ensembl Gene: ENSG00000185480 | OMIM ID: 613687 |
Expression of PARPBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PARPBP | 55010 | 227928_at | 0.9454 | 0.0984 | |
| GSE20347 | PARPBP | 55010 | 220060_s_at | 0.3200 | 0.0155 | |
| GSE23400 | PARPBP | 55010 | 220060_s_at | 0.1872 | 0.0000 | |
| GSE26886 | PARPBP | 55010 | 227928_at | -0.5835 | 0.0384 | |
| GSE29001 | PARPBP | 55010 | 220060_s_at | 0.2822 | 0.1801 | |
| GSE38129 | PARPBP | 55010 | 220060_s_at | 0.5526 | 0.0001 | |
| GSE45670 | PARPBP | 55010 | 227928_at | 0.2608 | 0.2663 | |
| GSE53622 | PARPBP | 55010 | 60391 | 1.0846 | 0.0000 | |
| GSE53624 | PARPBP | 55010 | 34833 | 0.6809 | 0.0000 | |
| GSE63941 | PARPBP | 55010 | 220060_s_at | 1.3040 | 0.0160 | |
| GSE77861 | PARPBP | 55010 | 220060_s_at | 0.1468 | 0.4421 | |
| SRP007169 | PARPBP | 55010 | RNAseq | 0.5875 | 0.2983 | |
| SRP008496 | PARPBP | 55010 | RNAseq | 0.4751 | 0.1485 | |
| SRP064894 | PARPBP | 55010 | RNAseq | 0.0659 | 0.7817 | |
| SRP133303 | PARPBP | 55010 | RNAseq | 0.6609 | 0.0177 | |
| SRP159526 | PARPBP | 55010 | RNAseq | 1.0617 | 0.0001 | |
| SRP193095 | PARPBP | 55010 | RNAseq | 0.1293 | 0.2899 | |
| SRP219564 | PARPBP | 55010 | RNAseq | 0.0205 | 0.9729 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by PARPBP expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of PARPBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PARPBP | 55010 | 3 | 2 | 25 | |
| GSE20123 | PARPBP | 55010 | 3 | 2 | 25 | |
| GSE43470 | PARPBP | 55010 | 2 | 0 | 41 | |
| GSE46452 | PARPBP | 55010 | 9 | 1 | 49 | |
| GSE47630 | PARPBP | 55010 | 9 | 1 | 30 | |
| GSE54993 | PARPBP | 55010 | 0 | 5 | 65 | |
| GSE54994 | PARPBP | 55010 | 4 | 2 | 47 | |
| GSE60625 | PARPBP | 55010 | 0 | 0 | 11 | |
| GSE74703 | PARPBP | 55010 | 2 | 0 | 34 | |
| GSE74704 | PARPBP | 55010 | 1 | 2 | 17 | |
| TCGA | PARPBP | 55010 | 18 | 11 | 67 |
Total number of gains: 51; Total number of losses: 26; Total Number of normals: 411.
Somatic mutations of PARPBP:
Generating mutation plots.
Highly correlated genes for PARPBP:
Showing top 20/515 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PARPBP | TICRR | 0.786487 | 4 | 0 | 4 |
| PARPBP | ESCO2 | 0.707623 | 5 | 0 | 5 |
| PARPBP | ATP6V0A2 | 0.703383 | 4 | 0 | 4 |
| PARPBP | CDCA5 | 0.696613 | 5 | 0 | 4 |
| PARPBP | NUF2 | 0.689005 | 5 | 0 | 4 |
| PARPBP | PRC1 | 0.688284 | 9 | 0 | 9 |
| PARPBP | E2F7 | 0.680721 | 5 | 0 | 4 |
| PARPBP | ZWILCH | 0.675726 | 10 | 0 | 10 |
| PARPBP | CCNB2 | 0.672851 | 8 | 0 | 8 |
| PARPBP | BIRC5 | 0.672012 | 8 | 0 | 6 |
| PARPBP | OIP5 | 0.670433 | 8 | 0 | 6 |
| PARPBP | DEPDC1B | 0.670404 | 5 | 0 | 5 |
| PARPBP | TTK | 0.669012 | 9 | 0 | 9 |
| PARPBP | ASPM | 0.668497 | 9 | 0 | 8 |
| PARPBP | SPC25 | 0.66751 | 9 | 0 | 7 |
| PARPBP | DTL | 0.662366 | 9 | 0 | 8 |
| PARPBP | TPX2 | 0.662251 | 9 | 0 | 7 |
| PARPBP | RMI1 | 0.661688 | 9 | 0 | 8 |
| PARPBP | SPAG5 | 0.660601 | 9 | 0 | 8 |
| PARPBP | CENPN | 0.659987 | 10 | 0 | 9 |
For details and further investigation, click here
