| Full name: bleomycin hydrolase | Alias Symbol: BH | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 642 | HGNC ID: HGNC:1059 | Ensembl Gene: ENSG00000108578 | OMIM ID: 602403 |
| Drug and gene relationship at DGIdb | |||
Expression of BLMH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BLMH | 642 | 202179_at | 0.3125 | 0.5314 | |
| GSE20347 | BLMH | 642 | 202179_at | 0.1623 | 0.5497 | |
| GSE23400 | BLMH | 642 | 202179_at | 0.4804 | 0.0000 | |
| GSE26886 | BLMH | 642 | 202179_at | -0.1338 | 0.7949 | |
| GSE29001 | BLMH | 642 | 202179_at | 0.1759 | 0.4380 | |
| GSE38129 | BLMH | 642 | 202179_at | 0.3847 | 0.0382 | |
| GSE45670 | BLMH | 642 | 202179_at | 0.0193 | 0.9589 | |
| GSE53622 | BLMH | 642 | 16724 | 0.1026 | 0.2711 | |
| GSE53624 | BLMH | 642 | 16724 | 0.0296 | 0.7513 | |
| GSE63941 | BLMH | 642 | 202179_at | 0.7003 | 0.5014 | |
| GSE77861 | BLMH | 642 | 202179_at | 1.0867 | 0.0314 | |
| GSE97050 | BLMH | 642 | A_23_P310911 | 0.0094 | 0.9766 | |
| SRP007169 | BLMH | 642 | RNAseq | 2.0125 | 0.0004 | |
| SRP008496 | BLMH | 642 | RNAseq | 1.9956 | 0.0000 | |
| SRP064894 | BLMH | 642 | RNAseq | 0.2665 | 0.0628 | |
| SRP133303 | BLMH | 642 | RNAseq | -0.1012 | 0.4999 | |
| SRP159526 | BLMH | 642 | RNAseq | 0.6163 | 0.0636 | |
| SRP193095 | BLMH | 642 | RNAseq | 0.0316 | 0.8805 | |
| SRP219564 | BLMH | 642 | RNAseq | -0.0383 | 0.9090 | |
| TCGA | BLMH | 642 | RNAseq | 0.2210 | 0.0058 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by BLMH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BLMH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BLMH | 642 | 7 | 2 | 21 | |
| GSE20123 | BLMH | 642 | 8 | 2 | 20 | |
| GSE43470 | BLMH | 642 | 0 | 1 | 42 | |
| GSE46452 | BLMH | 642 | 33 | 1 | 25 | |
| GSE47630 | BLMH | 642 | 7 | 1 | 32 | |
| GSE54993 | BLMH | 642 | 2 | 3 | 65 | |
| GSE54994 | BLMH | 642 | 7 | 5 | 41 | |
| GSE60625 | BLMH | 642 | 4 | 0 | 7 | |
| GSE74703 | BLMH | 642 | 0 | 1 | 35 | |
| GSE74704 | BLMH | 642 | 5 | 2 | 13 | |
| TCGA | BLMH | 642 | 20 | 10 | 66 |
Total number of gains: 93; Total number of losses: 28; Total Number of normals: 367.
Somatic mutations of BLMH:
Generating mutation plots.
Highly correlated genes for BLMH:
Showing top 20/194 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BLMH | SESN3 | 0.723314 | 3 | 0 | 3 |
| BLMH | AJUBA | 0.679266 | 3 | 0 | 3 |
| BLMH | SRXN1 | 0.650422 | 5 | 0 | 5 |
| BLMH | C2orf69 | 0.623581 | 3 | 0 | 3 |
| BLMH | IREB2 | 0.619454 | 3 | 0 | 3 |
| BLMH | SDE2 | 0.609418 | 3 | 0 | 3 |
| BLMH | KCNK1 | 0.606141 | 5 | 0 | 3 |
| BLMH | RTN4R | 0.605489 | 3 | 0 | 3 |
| BLMH | HDDC3 | 0.601992 | 3 | 0 | 3 |
| BLMH | SNRPB | 0.594648 | 5 | 0 | 3 |
| BLMH | MCTP2 | 0.592448 | 4 | 0 | 3 |
| BLMH | CDH13 | 0.591131 | 4 | 0 | 3 |
| BLMH | SAMD12 | 0.589431 | 4 | 0 | 3 |
| BLMH | NEFM | 0.586141 | 4 | 0 | 4 |
| BLMH | KREMEN1 | 0.585025 | 4 | 0 | 3 |
| BLMH | NSRP1 | 0.583349 | 4 | 0 | 3 |
| BLMH | SPIDR | 0.582955 | 6 | 0 | 6 |
| BLMH | LRP8 | 0.581554 | 3 | 0 | 3 |
| BLMH | NUP93 | 0.578979 | 6 | 0 | 4 |
| BLMH | NOP2 | 0.57873 | 3 | 0 | 3 |
For details and further investigation, click here
