| Full name: scaffold protein involved in DNA repair | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q11.21 | ||
| Entrez ID: 23514 | HGNC ID: HGNC:28971 | Ensembl Gene: ENSG00000164808 | OMIM ID: 615384 |
| Drug and gene relationship at DGIdb | |||
Expression of SPIDR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPIDR | 23514 | 228325_at | -0.4471 | 0.5218 | |
| GSE20347 | SPIDR | 23514 | 212523_s_at | 0.5598 | 0.0014 | |
| GSE23400 | SPIDR | 23514 | 212523_s_at | 0.6453 | 0.0000 | |
| GSE26886 | SPIDR | 23514 | 212523_s_at | -0.3702 | 0.3534 | |
| GSE29001 | SPIDR | 23514 | 212523_s_at | 0.8243 | 0.0430 | |
| GSE38129 | SPIDR | 23514 | 212523_s_at | 0.6002 | 0.0000 | |
| GSE45670 | SPIDR | 23514 | 212523_s_at | 0.3771 | 0.0996 | |
| GSE53622 | SPIDR | 23514 | 105170 | -0.1628 | 0.0686 | |
| GSE53624 | SPIDR | 23514 | 66529 | -0.2590 | 0.0002 | |
| GSE63941 | SPIDR | 23514 | 212523_s_at | -0.3615 | 0.3894 | |
| GSE77861 | SPIDR | 23514 | 212523_s_at | 0.3459 | 0.1614 | |
| SRP007169 | SPIDR | 23514 | RNAseq | 0.1257 | 0.7864 | |
| SRP008496 | SPIDR | 23514 | RNAseq | 0.7874 | 0.0393 | |
| SRP064894 | SPIDR | 23514 | RNAseq | 0.5561 | 0.0046 | |
| SRP133303 | SPIDR | 23514 | RNAseq | -0.0771 | 0.5824 | |
| SRP159526 | SPIDR | 23514 | RNAseq | 0.7198 | 0.0011 | |
| SRP193095 | SPIDR | 23514 | RNAseq | 0.3554 | 0.0010 | |
| SRP219564 | SPIDR | 23514 | RNAseq | 0.9223 | 0.0878 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPIDR expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SPIDR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPIDR | 23514 | 16 | 1 | 13 | |
| GSE20123 | SPIDR | 23514 | 16 | 1 | 13 | |
| GSE43470 | SPIDR | 23514 | 14 | 3 | 26 | |
| GSE46452 | SPIDR | 23514 | 22 | 2 | 35 | |
| GSE47630 | SPIDR | 23514 | 22 | 1 | 17 | |
| GSE54993 | SPIDR | 23514 | 1 | 16 | 53 | |
| GSE54994 | SPIDR | 23514 | 27 | 1 | 25 | |
| GSE60625 | SPIDR | 23514 | 0 | 5 | 6 | |
| GSE74703 | SPIDR | 23514 | 12 | 2 | 22 | |
| GSE74704 | SPIDR | 23514 | 12 | 0 | 8 | |
| TCGA | SPIDR | 23514 | 46 | 9 | 41 |
Total number of gains: 188; Total number of losses: 41; Total Number of normals: 259.
Somatic mutations of SPIDR:
Generating mutation plots.
Highly correlated genes for SPIDR:
Showing top 20/93 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPIDR | HSPE1 | 0.615482 | 5 | 0 | 4 |
| SPIDR | ZNF516 | 0.604811 | 4 | 0 | 3 |
| SPIDR | MCM4 | 0.603501 | 6 | 0 | 4 |
| SPIDR | HNRNPC | 0.599105 | 5 | 0 | 4 |
| SPIDR | DDX39A | 0.584016 | 5 | 0 | 4 |
| SPIDR | BLMH | 0.582955 | 6 | 0 | 6 |
| SPIDR | EPCAM | 0.579162 | 6 | 0 | 5 |
| SPIDR | MRPL15 | 0.577574 | 6 | 0 | 5 |
| SPIDR | KIAA0319 | 0.572934 | 3 | 0 | 3 |
| SPIDR | IMPAD1 | 0.571845 | 6 | 0 | 5 |
| SPIDR | GGH | 0.571215 | 5 | 0 | 4 |
| SPIDR | ABCC5 | 0.567064 | 6 | 0 | 4 |
| SPIDR | HNRNPU | 0.566575 | 6 | 0 | 4 |
| SPIDR | TCEA1 | 0.562969 | 5 | 0 | 3 |
| SPIDR | GCLC | 0.560957 | 6 | 0 | 4 |
| SPIDR | PTPN2 | 0.558895 | 4 | 0 | 3 |
| SPIDR | TBL1XR1 | 0.556401 | 5 | 0 | 4 |
| SPIDR | IMMT | 0.553395 | 5 | 0 | 3 |
| SPIDR | CHD1L | 0.55183 | 7 | 0 | 4 |
| SPIDR | MSH6 | 0.551728 | 7 | 0 | 6 |
For details and further investigation, click here
