| Full name: biogenesis of lysosomal organelles complex 1 subunit 6 | Alias Symbol: HPS9 | ||
| Type: protein-coding gene | Cytoband: 15q21.1 | ||
| Entrez ID: 26258 | HGNC ID: HGNC:8549 | Ensembl Gene: ENSG00000104164 | OMIM ID: 604310 |
Expression of BLOC1S6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BLOC1S6 | 26258 | 224892_at | -0.0066 | 0.9891 | |
| GSE26886 | BLOC1S6 | 26258 | 224892_at | 0.8679 | 0.0000 | |
| GSE45670 | BLOC1S6 | 26258 | 224892_at | -0.0057 | 0.9741 | |
| GSE53622 | BLOC1S6 | 26258 | 15707 | 0.0773 | 0.2944 | |
| GSE53624 | BLOC1S6 | 26258 | 14936 | 0.1749 | 0.0012 | |
| GSE63941 | BLOC1S6 | 26258 | 224892_at | -0.8767 | 0.0211 | |
| GSE77861 | BLOC1S6 | 26258 | 224892_at | 0.3422 | 0.0424 | |
| SRP007169 | BLOC1S6 | 26258 | RNAseq | 0.5696 | 0.1186 | |
| SRP008496 | BLOC1S6 | 26258 | RNAseq | 0.6739 | 0.0017 | |
| SRP064894 | BLOC1S6 | 26258 | RNAseq | 0.2244 | 0.1573 | |
| SRP133303 | BLOC1S6 | 26258 | RNAseq | 0.5077 | 0.0001 | |
| SRP159526 | BLOC1S6 | 26258 | RNAseq | 0.1260 | 0.7188 | |
| SRP193095 | BLOC1S6 | 26258 | RNAseq | 0.1289 | 0.2118 | |
| SRP219564 | BLOC1S6 | 26258 | RNAseq | -0.0438 | 0.8767 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BLOC1S6 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of BLOC1S6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BLOC1S6 | 26258 | 4 | 5 | 21 | |
| GSE20123 | BLOC1S6 | 26258 | 4 | 5 | 21 | |
| GSE43470 | BLOC1S6 | 26258 | 4 | 4 | 35 | |
| GSE46452 | BLOC1S6 | 26258 | 3 | 7 | 49 | |
| GSE47630 | BLOC1S6 | 26258 | 8 | 10 | 22 | |
| GSE54993 | BLOC1S6 | 26258 | 4 | 5 | 61 | |
| GSE54994 | BLOC1S6 | 26258 | 5 | 7 | 41 | |
| GSE60625 | BLOC1S6 | 26258 | 4 | 0 | 7 | |
| GSE74703 | BLOC1S6 | 26258 | 4 | 3 | 29 | |
| GSE74704 | BLOC1S6 | 26258 | 2 | 3 | 15 | |
| TCGA | BLOC1S6 | 26258 | 11 | 16 | 69 |
Total number of gains: 53; Total number of losses: 65; Total Number of normals: 370.
Somatic mutations of BLOC1S6:
Generating mutation plots.
Highly correlated genes for BLOC1S6:
Showing top 20/195 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BLOC1S6 | PRNP | 0.775697 | 3 | 0 | 3 |
| BLOC1S6 | CLIC4 | 0.742712 | 3 | 0 | 3 |
| BLOC1S6 | COL1A1 | 0.742644 | 3 | 0 | 3 |
| BLOC1S6 | ATP2B1 | 0.732027 | 3 | 0 | 3 |
| BLOC1S6 | PTPRZ1 | 0.721321 | 3 | 0 | 3 |
| BLOC1S6 | SLC30A7 | 0.721225 | 3 | 0 | 3 |
| BLOC1S6 | TPM1 | 0.714159 | 3 | 0 | 3 |
| BLOC1S6 | RHOQ | 0.705388 | 3 | 0 | 3 |
| BLOC1S6 | METTL22 | 0.693837 | 3 | 0 | 3 |
| BLOC1S6 | LPP | 0.691644 | 3 | 0 | 3 |
| BLOC1S6 | TNFRSF10B | 0.689589 | 3 | 0 | 3 |
| BLOC1S6 | CD44 | 0.682586 | 3 | 0 | 3 |
| BLOC1S6 | RCN2 | 0.677019 | 4 | 0 | 4 |
| BLOC1S6 | PIKFYVE | 0.674047 | 3 | 0 | 3 |
| BLOC1S6 | ADSL | 0.665735 | 4 | 0 | 4 |
| BLOC1S6 | FOXN2 | 0.66344 | 3 | 0 | 3 |
| BLOC1S6 | VOPP1 | 0.662521 | 3 | 0 | 3 |
| BLOC1S6 | FAM220A | 0.662308 | 3 | 0 | 3 |
| BLOC1S6 | CBLB | 0.659558 | 3 | 0 | 3 |
| BLOC1S6 | LRRC59 | 0.657151 | 3 | 0 | 3 |
For details and further investigation, click here
