| Full name: BTG anti-proliferation factor 2 | Alias Symbol: PC3|TIS21|MGC126063|MGC126064|APRO1 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 7832 | HGNC ID: HGNC:1131 | Ensembl Gene: ENSG00000159388 | OMIM ID: 601597 |
Screen Evidence:
| |||
Expression of BTG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BTG2 | 7832 | 201236_s_at | -1.2370 | 0.1316 | |
| GSE20347 | BTG2 | 7832 | 201236_s_at | 0.0053 | 0.9891 | |
| GSE23400 | BTG2 | 7832 | 201236_s_at | -0.4612 | 0.0081 | |
| GSE26886 | BTG2 | 7832 | 201236_s_at | 0.5454 | 0.0556 | |
| GSE29001 | BTG2 | 7832 | 201236_s_at | -0.2256 | 0.6116 | |
| GSE38129 | BTG2 | 7832 | 201236_s_at | -0.5004 | 0.1345 | |
| GSE45670 | BTG2 | 7832 | 201236_s_at | -0.7612 | 0.0041 | |
| GSE53622 | BTG2 | 7832 | 139044 | -0.9988 | 0.0000 | |
| GSE53624 | BTG2 | 7832 | 139044 | -0.8360 | 0.0000 | |
| GSE63941 | BTG2 | 7832 | 201236_s_at | 0.2763 | 0.7368 | |
| GSE77861 | BTG2 | 7832 | 201236_s_at | 0.6601 | 0.1003 | |
| GSE97050 | BTG2 | 7832 | A_23_P62901 | -0.9044 | 0.2987 | |
| SRP007169 | BTG2 | 7832 | RNAseq | -0.5821 | 0.1678 | |
| SRP008496 | BTG2 | 7832 | RNAseq | -0.8073 | 0.0351 | |
| SRP064894 | BTG2 | 7832 | RNAseq | -1.0543 | 0.0089 | |
| SRP133303 | BTG2 | 7832 | RNAseq | -0.2480 | 0.3171 | |
| SRP159526 | BTG2 | 7832 | RNAseq | -0.4278 | 0.5024 | |
| SRP193095 | BTG2 | 7832 | RNAseq | 0.5082 | 0.0622 | |
| SRP219564 | BTG2 | 7832 | RNAseq | -0.7929 | 0.3758 | |
| TCGA | BTG2 | 7832 | RNAseq | -0.4053 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by BTG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BTG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BTG2 | 7832 | 11 | 0 | 19 | |
| GSE20123 | BTG2 | 7832 | 11 | 0 | 19 | |
| GSE43470 | BTG2 | 7832 | 6 | 0 | 37 | |
| GSE46452 | BTG2 | 7832 | 3 | 1 | 55 | |
| GSE47630 | BTG2 | 7832 | 14 | 0 | 26 | |
| GSE54993 | BTG2 | 7832 | 0 | 6 | 64 | |
| GSE54994 | BTG2 | 7832 | 15 | 0 | 38 | |
| GSE60625 | BTG2 | 7832 | 0 | 0 | 11 | |
| GSE74703 | BTG2 | 7832 | 6 | 0 | 30 | |
| GSE74704 | BTG2 | 7832 | 5 | 0 | 15 | |
| TCGA | BTG2 | 7832 | 44 | 4 | 48 |
Total number of gains: 115; Total number of losses: 11; Total Number of normals: 362.
Somatic mutations of BTG2:
Generating mutation plots.
Highly correlated genes for BTG2:
Showing top 20/646 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BTG2 | LRP6 | 0.778351 | 3 | 0 | 3 |
| BTG2 | SLC35F1 | 0.741788 | 3 | 0 | 3 |
| BTG2 | SOX10 | 0.736545 | 3 | 0 | 3 |
| BTG2 | PI16 | 0.719393 | 4 | 0 | 4 |
| BTG2 | TOB2 | 0.716305 | 3 | 0 | 3 |
| BTG2 | C1orf198 | 0.713027 | 3 | 0 | 3 |
| BTG2 | FXYD1 | 0.703659 | 5 | 0 | 4 |
| BTG2 | DDHD2 | 0.698717 | 3 | 0 | 3 |
| BTG2 | RGS2 | 0.69819 | 10 | 0 | 10 |
| BTG2 | CYP21A2 | 0.697926 | 3 | 0 | 3 |
| BTG2 | FGFR1 | 0.694938 | 4 | 0 | 3 |
| BTG2 | RBMX2 | 0.694415 | 4 | 0 | 3 |
| BTG2 | PARD3B | 0.691248 | 4 | 0 | 3 |
| BTG2 | THAP8 | 0.690669 | 3 | 0 | 3 |
| BTG2 | COL28A1 | 0.690464 | 3 | 0 | 3 |
| BTG2 | RHOB | 0.689312 | 10 | 0 | 8 |
| BTG2 | CNTLN | 0.688991 | 3 | 0 | 3 |
| BTG2 | PRKCA | 0.68812 | 5 | 0 | 4 |
| BTG2 | XKR4 | 0.687008 | 5 | 0 | 4 |
| BTG2 | JMY | 0.68513 | 3 | 0 | 3 |
For details and further investigation, click here
