| Full name: solute carrier family 7 member 7 | Alias Symbol: y+LAT-1 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 9056 | HGNC ID: HGNC:11065 | Ensembl Gene: ENSG00000155465 | OMIM ID: 603593 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC7A7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC7A7 | 9056 | 204588_s_at | 0.7677 | 0.3658 | |
| GSE20347 | SLC7A7 | 9056 | 204588_s_at | 0.4641 | 0.0023 | |
| GSE23400 | SLC7A7 | 9056 | 204588_s_at | 0.1272 | 0.0090 | |
| GSE26886 | SLC7A7 | 9056 | 204588_s_at | 0.6435 | 0.0091 | |
| GSE29001 | SLC7A7 | 9056 | 204588_s_at | 0.6441 | 0.0085 | |
| GSE38129 | SLC7A7 | 9056 | 204588_s_at | 0.6267 | 0.0001 | |
| GSE45670 | SLC7A7 | 9056 | 204588_s_at | 0.3541 | 0.1970 | |
| GSE53622 | SLC7A7 | 9056 | 102519 | 1.1429 | 0.0000 | |
| GSE53624 | SLC7A7 | 9056 | 102519 | 1.3738 | 0.0000 | |
| GSE63941 | SLC7A7 | 9056 | 204588_s_at | -1.4861 | 0.0019 | |
| GSE77861 | SLC7A7 | 9056 | 204588_s_at | 0.2594 | 0.0325 | |
| GSE97050 | SLC7A7 | 9056 | A_23_P99642 | 0.4488 | 0.2002 | |
| SRP007169 | SLC7A7 | 9056 | RNAseq | 3.4581 | 0.0002 | |
| SRP008496 | SLC7A7 | 9056 | RNAseq | 2.1045 | 0.0006 | |
| SRP064894 | SLC7A7 | 9056 | RNAseq | 1.9341 | 0.0000 | |
| SRP133303 | SLC7A7 | 9056 | RNAseq | 1.5326 | 0.0000 | |
| SRP159526 | SLC7A7 | 9056 | RNAseq | 0.9634 | 0.1080 | |
| SRP193095 | SLC7A7 | 9056 | RNAseq | 0.6019 | 0.1180 | |
| SRP219564 | SLC7A7 | 9056 | RNAseq | 1.7884 | 0.0026 | |
| TCGA | SLC7A7 | 9056 | RNAseq | 0.3096 | 0.0201 |
Upregulated datasets: 7; Downregulated datasets: 1.
Survival by SLC7A7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC7A7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC7A7 | 9056 | 9 | 2 | 19 | |
| GSE20123 | SLC7A7 | 9056 | 9 | 2 | 19 | |
| GSE43470 | SLC7A7 | 9056 | 7 | 2 | 34 | |
| GSE46452 | SLC7A7 | 9056 | 17 | 2 | 40 | |
| GSE47630 | SLC7A7 | 9056 | 11 | 10 | 19 | |
| GSE54993 | SLC7A7 | 9056 | 3 | 11 | 56 | |
| GSE54994 | SLC7A7 | 9056 | 18 | 5 | 30 | |
| GSE60625 | SLC7A7 | 9056 | 0 | 2 | 9 | |
| GSE74703 | SLC7A7 | 9056 | 6 | 2 | 28 | |
| GSE74704 | SLC7A7 | 9056 | 4 | 1 | 15 | |
| TCGA | SLC7A7 | 9056 | 25 | 17 | 54 |
Total number of gains: 109; Total number of losses: 56; Total Number of normals: 323.
Somatic mutations of SLC7A7:
Generating mutation plots.
Highly correlated genes for SLC7A7:
Showing top 20/680 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC7A7 | TMEM150B | 0.772289 | 3 | 0 | 3 |
| SLC7A7 | PLA2G7 | 0.767662 | 12 | 0 | 12 |
| SLC7A7 | FCER1G | 0.767592 | 11 | 0 | 10 |
| SLC7A7 | SLAMF8 | 0.760203 | 11 | 0 | 11 |
| SLC7A7 | MS4A7 | 0.759685 | 4 | 0 | 4 |
| SLC7A7 | FPR3 | 0.741117 | 10 | 0 | 9 |
| SLC7A7 | C3AR1 | 0.736088 | 11 | 0 | 10 |
| SLC7A7 | C1QB | 0.733921 | 12 | 0 | 11 |
| SLC7A7 | CD14 | 0.725025 | 12 | 0 | 11 |
| SLC7A7 | CCR1 | 0.724992 | 12 | 0 | 10 |
| SLC7A7 | CD300LF | 0.722704 | 6 | 0 | 5 |
| SLC7A7 | CTBP2 | 0.722282 | 3 | 0 | 3 |
| SLC7A7 | TYROBP | 0.719882 | 12 | 0 | 10 |
| SLC7A7 | LCP2 | 0.718225 | 9 | 0 | 9 |
| SLC7A7 | FCGR1B | 0.71329 | 10 | 0 | 8 |
| SLC7A7 | CD163 | 0.703042 | 12 | 0 | 11 |
| SLC7A7 | LAPTM5 | 0.700285 | 10 | 0 | 9 |
| SLC7A7 | ITGB2 | 0.698104 | 11 | 0 | 11 |
| SLC7A7 | CCL18 | 0.695427 | 11 | 0 | 11 |
| SLC7A7 | IL4I1 | 0.69541 | 7 | 0 | 7 |
For details and further investigation, click here
