| Full name: chromosome 5 open reading frame 34 | Alias Symbol: FLJ32363 | ||
| Type: protein-coding gene | Cytoband: 5p12 | ||
| Entrez ID: 375444 | HGNC ID: HGNC:24738 | Ensembl Gene: ENSG00000172244 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C5orf34:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C5orf34 | 375444 | 229886_at | 0.5146 | 0.3872 | |
| GSE26886 | C5orf34 | 375444 | 229886_at | 0.9079 | 0.0463 | |
| GSE45670 | C5orf34 | 375444 | 229886_at | 0.3322 | 0.2471 | |
| GSE53622 | C5orf34 | 375444 | 35952 | 0.8736 | 0.0000 | |
| GSE53624 | C5orf34 | 375444 | 35952 | 0.8922 | 0.0000 | |
| GSE63941 | C5orf34 | 375444 | 229886_at | 0.9030 | 0.1730 | |
| GSE77861 | C5orf34 | 375444 | 229886_at | 0.0998 | 0.6074 | |
| GSE97050 | C5orf34 | 375444 | A_23_P403081 | -0.0980 | 0.8463 | |
| SRP007169 | C5orf34 | 375444 | RNAseq | 1.3437 | 0.0858 | |
| SRP064894 | C5orf34 | 375444 | RNAseq | 0.9954 | 0.0001 | |
| SRP133303 | C5orf34 | 375444 | RNAseq | 0.6589 | 0.0052 | |
| SRP159526 | C5orf34 | 375444 | RNAseq | 1.7662 | 0.0020 | |
| SRP193095 | C5orf34 | 375444 | RNAseq | 0.4463 | 0.0013 | |
| SRP219564 | C5orf34 | 375444 | RNAseq | 0.7172 | 0.0920 | |
| TCGA | C5orf34 | 375444 | RNAseq | 1.0749 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by C5orf34 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C5orf34:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C5orf34 | 375444 | 10 | 0 | 20 | |
| GSE20123 | C5orf34 | 375444 | 10 | 0 | 20 | |
| GSE43470 | C5orf34 | 375444 | 16 | 0 | 27 | |
| GSE46452 | C5orf34 | 375444 | 5 | 22 | 32 | |
| GSE47630 | C5orf34 | 375444 | 6 | 12 | 22 | |
| GSE54993 | C5orf34 | 375444 | 6 | 3 | 61 | |
| GSE54994 | C5orf34 | 375444 | 24 | 2 | 27 | |
| GSE60625 | C5orf34 | 375444 | 0 | 0 | 11 | |
| GSE74703 | C5orf34 | 375444 | 13 | 0 | 23 | |
| GSE74704 | C5orf34 | 375444 | 9 | 0 | 11 | |
| TCGA | C5orf34 | 375444 | 53 | 6 | 37 |
Total number of gains: 152; Total number of losses: 45; Total Number of normals: 291.
Somatic mutations of C5orf34:
Generating mutation plots.
Highly correlated genes for C5orf34:
Showing top 20/100 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C5orf34 | LSM8 | 0.680841 | 3 | 0 | 3 |
| C5orf34 | TOMM34 | 0.660996 | 3 | 0 | 3 |
| C5orf34 | SKP2 | 0.637177 | 7 | 0 | 6 |
| C5orf34 | METTL18 | 0.63176 | 4 | 0 | 3 |
| C5orf34 | IRAK1 | 0.625983 | 4 | 0 | 3 |
| C5orf34 | FAM24B | 0.625666 | 3 | 0 | 3 |
| C5orf34 | KLC4 | 0.624614 | 3 | 0 | 3 |
| C5orf34 | DCPS | 0.622267 | 4 | 0 | 3 |
| C5orf34 | SMARCB1 | 0.61493 | 4 | 0 | 3 |
| C5orf34 | CST2 | 0.613444 | 3 | 0 | 3 |
| C5orf34 | GEN1 | 0.603071 | 4 | 0 | 4 |
| C5orf34 | ARHGAP11A | 0.599401 | 5 | 0 | 3 |
| C5orf34 | FANCB | 0.596844 | 3 | 0 | 3 |
| C5orf34 | CECR2 | 0.595125 | 3 | 0 | 3 |
| C5orf34 | MRPS2 | 0.592945 | 4 | 0 | 3 |
| C5orf34 | SLC22A16 | 0.592434 | 4 | 0 | 3 |
| C5orf34 | TBC1D1 | 0.588417 | 5 | 0 | 3 |
| C5orf34 | OTX1 | 0.588219 | 4 | 0 | 3 |
| C5orf34 | TP53BP1 | 0.587912 | 4 | 0 | 4 |
| C5orf34 | POLR2D | 0.585298 | 4 | 0 | 3 |
For details and further investigation, click here
