| Full name: CDK2 associated cullin domain 1 | Alias Symbol: FLJ40409|MGC33215|CAC1 | ||
| Type: protein-coding gene | Cytoband: 10q26.11 | ||
| Entrez ID: 143384 | HGNC ID: HGNC:23727 | Ensembl Gene: ENSG00000151893 | OMIM ID: |
Expression of CACUL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CACUL1 | 143384 | 225192_at | 0.3325 | 0.3332 | |
| GSE26886 | CACUL1 | 143384 | 225192_at | -0.5670 | 0.0107 | |
| GSE45670 | CACUL1 | 143384 | 225192_at | 0.0808 | 0.6053 | |
| GSE53622 | CACUL1 | 143384 | 19247 | -0.2531 | 0.0005 | |
| GSE53624 | CACUL1 | 143384 | 19247 | -0.3609 | 0.0000 | |
| GSE63941 | CACUL1 | 143384 | 225192_at | 0.1621 | 0.5455 | |
| GSE77861 | CACUL1 | 143384 | 225192_at | -0.2318 | 0.3367 | |
| SRP007169 | CACUL1 | 143384 | RNAseq | -1.0098 | 0.0079 | |
| SRP008496 | CACUL1 | 143384 | RNAseq | -0.9173 | 0.0000 | |
| SRP064894 | CACUL1 | 143384 | RNAseq | -0.4104 | 0.0011 | |
| SRP133303 | CACUL1 | 143384 | RNAseq | 0.1466 | 0.3281 | |
| SRP159526 | CACUL1 | 143384 | RNAseq | -0.4227 | 0.0558 | |
| SRP193095 | CACUL1 | 143384 | RNAseq | -0.2780 | 0.0223 | |
| SRP219564 | CACUL1 | 143384 | RNAseq | -0.3000 | 0.3058 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CACUL1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CACUL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CACUL1 | 143384 | 1 | 7 | 22 | |
| GSE20123 | CACUL1 | 143384 | 1 | 7 | 22 | |
| GSE43470 | CACUL1 | 143384 | 0 | 9 | 34 | |
| GSE46452 | CACUL1 | 143384 | 0 | 11 | 48 | |
| GSE47630 | CACUL1 | 143384 | 2 | 14 | 24 | |
| GSE54993 | CACUL1 | 143384 | 8 | 0 | 62 | |
| GSE54994 | CACUL1 | 143384 | 1 | 9 | 43 | |
| GSE60625 | CACUL1 | 143384 | 0 | 0 | 11 | |
| GSE74703 | CACUL1 | 143384 | 0 | 6 | 30 | |
| GSE74704 | CACUL1 | 143384 | 1 | 3 | 16 | |
| TCGA | CACUL1 | 143384 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 94; Total Number of normals: 376.
Somatic mutations of CACUL1:
Generating mutation plots.
Highly correlated genes for CACUL1:
Showing top 20/147 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CACUL1 | TMEM69 | 0.71639 | 3 | 0 | 3 |
| CACUL1 | ZDHHC6 | 0.693616 | 5 | 0 | 5 |
| CACUL1 | MAP4K5 | 0.678449 | 3 | 0 | 3 |
| CACUL1 | PSMC6 | 0.66818 | 5 | 0 | 4 |
| CACUL1 | SEC24B | 0.654168 | 3 | 0 | 3 |
| CACUL1 | TIAL1 | 0.650737 | 3 | 0 | 3 |
| CACUL1 | LACTB | 0.649381 | 4 | 0 | 3 |
| CACUL1 | CEPT1 | 0.649172 | 3 | 0 | 3 |
| CACUL1 | DHX32 | 0.64347 | 5 | 0 | 5 |
| CACUL1 | PITHD1 | 0.642116 | 3 | 0 | 3 |
| CACUL1 | UBE2D1 | 0.636354 | 5 | 0 | 5 |
| CACUL1 | PI4K2A | 0.631797 | 6 | 0 | 6 |
| CACUL1 | GNG12 | 0.631265 | 5 | 0 | 4 |
| CACUL1 | SRP72 | 0.631022 | 3 | 0 | 3 |
| CACUL1 | GCH1 | 0.625102 | 3 | 0 | 3 |
| CACUL1 | NRAS | 0.618296 | 4 | 0 | 3 |
| CACUL1 | STYX | 0.616581 | 3 | 0 | 3 |
| CACUL1 | LGALS3 | 0.615353 | 4 | 0 | 4 |
| CACUL1 | MREG | 0.610542 | 4 | 0 | 3 |
| CACUL1 | ANXA7 | 0.609724 | 3 | 0 | 3 |
For details and further investigation, click here
