| Full name: ubiquitin conjugating enzyme E2 D1 | Alias Symbol: UbcH5A|UBCH5|UBC4/5|E2(17)KB1 | ||
| Type: protein-coding gene | Cytoband: 10q21.1 | ||
| Entrez ID: 7321 | HGNC ID: HGNC:12474 | Ensembl Gene: ENSG00000072401 | OMIM ID: 602961 |
| Drug and gene relationship at DGIdb | |||
Expression of UBE2D1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2D1 | 7321 | 211764_s_at | 0.4235 | 0.3351 | |
| GSE20347 | UBE2D1 | 7321 | 211764_s_at | -0.6359 | 0.0014 | |
| GSE23400 | UBE2D1 | 7321 | 211764_s_at | -0.2172 | 0.0050 | |
| GSE26886 | UBE2D1 | 7321 | 211764_s_at | -1.0536 | 0.0000 | |
| GSE29001 | UBE2D1 | 7321 | 211764_s_at | -0.5256 | 0.1795 | |
| GSE38129 | UBE2D1 | 7321 | 211764_s_at | -0.3922 | 0.0221 | |
| GSE45670 | UBE2D1 | 7321 | 211764_s_at | -0.1012 | 0.5381 | |
| GSE53622 | UBE2D1 | 7321 | 78934 | -0.1516 | 0.0038 | |
| GSE53624 | UBE2D1 | 7321 | 78934 | -0.4016 | 0.0000 | |
| GSE63941 | UBE2D1 | 7321 | 211764_s_at | -0.5754 | 0.1632 | |
| GSE77861 | UBE2D1 | 7321 | 211764_s_at | -0.7656 | 0.0197 | |
| GSE97050 | UBE2D1 | 7321 | A_24_P13032 | 0.0828 | 0.8106 | |
| SRP007169 | UBE2D1 | 7321 | RNAseq | -1.4144 | 0.0031 | |
| SRP008496 | UBE2D1 | 7321 | RNAseq | -1.3635 | 0.0000 | |
| SRP064894 | UBE2D1 | 7321 | RNAseq | -0.6692 | 0.0034 | |
| SRP133303 | UBE2D1 | 7321 | RNAseq | 0.3128 | 0.0983 | |
| SRP159526 | UBE2D1 | 7321 | RNAseq | -0.5905 | 0.0507 | |
| SRP193095 | UBE2D1 | 7321 | RNAseq | -0.5790 | 0.0007 | |
| SRP219564 | UBE2D1 | 7321 | RNAseq | -0.2886 | 0.3226 | |
| TCGA | UBE2D1 | 7321 | RNAseq | 0.1944 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by UBE2D1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2D1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2D1 | 7321 | 2 | 6 | 22 | |
| GSE20123 | UBE2D1 | 7321 | 2 | 6 | 22 | |
| GSE43470 | UBE2D1 | 7321 | 2 | 5 | 36 | |
| GSE46452 | UBE2D1 | 7321 | 0 | 12 | 47 | |
| GSE47630 | UBE2D1 | 7321 | 4 | 12 | 24 | |
| GSE54993 | UBE2D1 | 7321 | 9 | 0 | 61 | |
| GSE54994 | UBE2D1 | 7321 | 3 | 10 | 40 | |
| GSE60625 | UBE2D1 | 7321 | 0 | 0 | 11 | |
| GSE74703 | UBE2D1 | 7321 | 2 | 3 | 31 | |
| GSE74704 | UBE2D1 | 7321 | 1 | 4 | 15 | |
| TCGA | UBE2D1 | 7321 | 10 | 23 | 63 |
Total number of gains: 35; Total number of losses: 81; Total Number of normals: 372.
Somatic mutations of UBE2D1:
Generating mutation plots.
Highly correlated genes for UBE2D1:
Showing top 20/479 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2D1 | CD2AP | 0.696224 | 7 | 0 | 6 |
| UBE2D1 | C3orf80 | 0.692926 | 3 | 0 | 3 |
| UBE2D1 | EPG5 | 0.679477 | 3 | 0 | 3 |
| UBE2D1 | RAP1GDS1 | 0.675519 | 9 | 0 | 8 |
| UBE2D1 | LINC00551 | 0.670092 | 3 | 0 | 3 |
| UBE2D1 | SLC44A3 | 0.65865 | 4 | 0 | 3 |
| UBE2D1 | TTC37 | 0.653013 | 4 | 0 | 3 |
| UBE2D1 | SNAP29 | 0.649848 | 4 | 0 | 4 |
| UBE2D1 | STXBP5 | 0.649705 | 5 | 0 | 5 |
| UBE2D1 | ALAS1 | 0.647962 | 5 | 0 | 4 |
| UBE2D1 | CTTNBP2NL | 0.647631 | 5 | 0 | 4 |
| UBE2D1 | ACOX1 | 0.638392 | 7 | 0 | 6 |
| UBE2D1 | GOLGA4 | 0.636972 | 6 | 0 | 5 |
| UBE2D1 | GSKIP | 0.63662 | 5 | 0 | 4 |
| UBE2D1 | CACUL1 | 0.636354 | 5 | 0 | 5 |
| UBE2D1 | CCDC6 | 0.636198 | 9 | 0 | 7 |
| UBE2D1 | SPAG1 | 0.634318 | 9 | 0 | 8 |
| UBE2D1 | AKAP11 | 0.632998 | 3 | 0 | 3 |
| UBE2D1 | SOCS6 | 0.632458 | 5 | 0 | 5 |
| UBE2D1 | UBE2E1 | 0.631868 | 9 | 0 | 8 |
For details and further investigation, click here
