| Full name: calbindin 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q21.3 | ||
| Entrez ID: 793 | HGNC ID: HGNC:1434 | Ensembl Gene: ENSG00000104327 | OMIM ID: 114050 |
| Drug and gene relationship at DGIdb | |||
CALB1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04961 | Endocrine and other factor-regulated calcium reabsorption |
Expression of CALB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CALB1 | 793 | 205625_s_at | 1.3512 | 0.3613 | |
| GSE20347 | CALB1 | 793 | 205625_s_at | 2.0896 | 0.0269 | |
| GSE23400 | CALB1 | 793 | 205625_s_at | 1.5320 | 0.0000 | |
| GSE26886 | CALB1 | 793 | 205626_s_at | 1.7962 | 0.0090 | |
| GSE29001 | CALB1 | 793 | 205625_s_at | 1.9178 | 0.0112 | |
| GSE38129 | CALB1 | 793 | 205625_s_at | 2.2700 | 0.0014 | |
| GSE45670 | CALB1 | 793 | 205625_s_at | 2.8927 | 0.0527 | |
| GSE53622 | CALB1 | 793 | 23617 | 1.9825 | 0.0000 | |
| GSE53624 | CALB1 | 793 | 17049 | 3.8079 | 0.0000 | |
| GSE63941 | CALB1 | 793 | 205626_s_at | 3.7727 | 0.2003 | |
| GSE77861 | CALB1 | 793 | 205626_s_at | 1.1412 | 0.2673 | |
| GSE97050 | CALB1 | 793 | A_23_P43197 | 0.5607 | 0.2967 | |
| SRP007169 | CALB1 | 793 | RNAseq | 9.1848 | 0.0000 | |
| TCGA | CALB1 | 793 | RNAseq | 1.3361 | 0.0200 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by CALB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CALB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CALB1 | 793 | 14 | 1 | 15 | |
| GSE20123 | CALB1 | 793 | 15 | 1 | 14 | |
| GSE43470 | CALB1 | 793 | 20 | 1 | 22 | |
| GSE46452 | CALB1 | 793 | 22 | 0 | 37 | |
| GSE47630 | CALB1 | 793 | 24 | 0 | 16 | |
| GSE54993 | CALB1 | 793 | 0 | 20 | 50 | |
| GSE54994 | CALB1 | 793 | 33 | 1 | 19 | |
| GSE60625 | CALB1 | 793 | 0 | 4 | 7 | |
| GSE74703 | CALB1 | 793 | 17 | 1 | 18 | |
| GSE74704 | CALB1 | 793 | 10 | 0 | 10 | |
| TCGA | CALB1 | 793 | 55 | 1 | 40 |
Total number of gains: 210; Total number of losses: 30; Total Number of normals: 248.
Somatic mutations of CALB1:
Generating mutation plots.
Highly correlated genes for CALB1:
Showing top 20/101 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CALB1 | SLAMF9 | 0.779995 | 3 | 0 | 3 |
| CALB1 | MRGPRX3 | 0.703254 | 3 | 0 | 3 |
| CALB1 | OGDHL | 0.68437 | 3 | 0 | 3 |
| CALB1 | LRRCC1 | 0.682594 | 3 | 0 | 3 |
| CALB1 | PITPNB | 0.64609 | 3 | 0 | 3 |
| CALB1 | GABRG3 | 0.619342 | 4 | 0 | 3 |
| CALB1 | LIN28B | 0.617566 | 3 | 0 | 3 |
| CALB1 | ENPEP | 0.613091 | 3 | 0 | 3 |
| CALB1 | PLA2R1 | 0.598823 | 5 | 0 | 4 |
| CALB1 | TCHH | 0.595894 | 6 | 0 | 4 |
| CALB1 | DSC1 | 0.581994 | 6 | 0 | 3 |
| CALB1 | TWIST1 | 0.581705 | 4 | 0 | 3 |
| CALB1 | POPDC3 | 0.580482 | 6 | 0 | 4 |
| CALB1 | CCT6A | 0.577927 | 6 | 0 | 4 |
| CALB1 | TNFRSF18 | 0.577166 | 5 | 0 | 4 |
| CALB1 | DDRGK1 | 0.577067 | 4 | 0 | 3 |
| CALB1 | SCN9A | 0.571938 | 6 | 0 | 3 |
| CALB1 | TENM2 | 0.571517 | 4 | 0 | 3 |
| CALB1 | ASPRV1 | 0.571338 | 7 | 0 | 4 |
| CALB1 | CHST7 | 0.569585 | 10 | 0 | 8 |
For details and further investigation, click here
