CCDC138

 

Full name: coiled-coil domain containing 138 Alias Symbol: FLJ32745
Type: protein-coding gene Cytoband: 2q13
Entrez ID: 165055 HGNC ID: HGNC:26531 Ensembl Gene: ENSG00000163006 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of CCDC138:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CCDC138 165055 235644_at 0.5959 0.2751
GSE26886 CCDC138 165055 235644_at 0.3427 0.1261
GSE45670 CCDC138 165055 235644_at 0.6619 0.0020
GSE53622 CCDC138 165055 90852 0.6781 0.0000
GSE53624 CCDC138 165055 90852 0.8544 0.0000
GSE63941 CCDC138 165055 235644_at 1.9500 0.0037
GSE77861 CCDC138 165055 235644_at 0.2383 0.2027
SRP007169 CCDC138 165055 RNAseq 0.8624 0.0537
SRP008496 CCDC138 165055 RNAseq 1.0673 0.0066
SRP064894 CCDC138 165055 RNAseq 0.6175 0.0310
SRP133303 CCDC138 165055 RNAseq 0.4355 0.0357
SRP159526 CCDC138 165055 RNAseq 0.6449 0.0922
SRP193095 CCDC138 165055 RNAseq 0.1690 0.2256
SRP219564 CCDC138 165055 RNAseq 0.0743 0.8821
TCGA CCDC138 165055 RNAseq 0.6656 0.0000

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by CCDC138 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CCDC138:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CCDC138 165055 4 2 24
GSE20123 CCDC138 165055 4 2 24
GSE43470 CCDC138 165055 3 1 39
GSE46452 CCDC138 165055 1 4 54
GSE47630 CCDC138 165055 7 0 33
GSE54993 CCDC138 165055 0 6 64
GSE54994 CCDC138 165055 10 0 43
GSE60625 CCDC138 165055 0 3 8
GSE74703 CCDC138 165055 3 1 32
GSE74704 CCDC138 165055 2 2 16
TCGA CCDC138 165055 31 6 59

Total number of gains: 65; Total number of losses: 27; Total Number of normals: 396.  

 

Somatic mutations of CCDC138:

 

Generating mutation plots.

 

Highly correlated genes for CCDC138:

 

Showing top 20/652 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CCDC138CKAP2L0.716749606
CCDC138LRP80.712701303
CCDC138TTK0.70298707
CCDC138BUB10.701969808
CCDC138DDIAS0.698358606
CCDC138MZT10.693078505
CCDC138NIPA20.692151303
CCDC138KPNA20.69161404
CCDC138YES10.682163303
CCDC138SFPQ0.681222303
CCDC138NCAPH0.677964504
CCDC138TSN0.674185504
CCDC138CYCS0.671621404
CCDC138AURKB0.669199504
CCDC138STIL0.668044404
CCDC138DSCC10.665231505
CCDC138NUP350.664697606
CCDC138NDUFAF40.663602404
CCDC138CDK10.660087706
CCDC138GPR1800.656786505

For details and further investigation, click here