| Full name: coiled-coil domain containing 178 | Alias Symbol: FLJ44050 | ||
| Type: protein-coding gene | Cytoband: 18q12.1 | ||
| Entrez ID: 374864 | HGNC ID: HGNC:29588 | Ensembl Gene: ENSG00000166960 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC178:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC178 | 374864 | 1558820_a_at | -0.4376 | 0.4799 | |
| GSE26886 | CCDC178 | 374864 | 1558820_a_at | -0.3087 | 0.0182 | |
| GSE45670 | CCDC178 | 374864 | 1558820_a_at | -0.5544 | 0.0005 | |
| GSE53622 | CCDC178 | 374864 | 131658 | -0.9032 | 0.0000 | |
| GSE53624 | CCDC178 | 374864 | 131658 | -1.0364 | 0.0000 | |
| GSE63941 | CCDC178 | 374864 | 1558820_a_at | -0.2180 | 0.4511 | |
| GSE77861 | CCDC178 | 374864 | 1558820_a_at | -0.0809 | 0.5451 | |
| SRP133303 | CCDC178 | 374864 | RNAseq | -2.0629 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CCDC178 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CCDC178:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC178 | 374864 | 1 | 6 | 23 | |
| GSE20123 | CCDC178 | 374864 | 1 | 7 | 22 | |
| GSE43470 | CCDC178 | 374864 | 0 | 3 | 40 | |
| GSE46452 | CCDC178 | 374864 | 1 | 25 | 33 | |
| GSE47630 | CCDC178 | 374864 | 5 | 20 | 15 | |
| GSE54993 | CCDC178 | 374864 | 8 | 1 | 61 | |
| GSE54994 | CCDC178 | 374864 | 1 | 16 | 36 | |
| GSE60625 | CCDC178 | 374864 | 0 | 4 | 7 | |
| GSE74703 | CCDC178 | 374864 | 0 | 3 | 33 | |
| GSE74704 | CCDC178 | 374864 | 0 | 6 | 14 | |
| TCGA | CCDC178 | 374864 | 15 | 36 | 45 |
Total number of gains: 32; Total number of losses: 127; Total Number of normals: 329.
Somatic mutations of CCDC178:
Generating mutation plots.
Highly correlated genes for CCDC178:
Showing top 20/385 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC178 | ARHGAP6 | 0.741938 | 4 | 0 | 4 |
| CCDC178 | CADM3 | 0.721569 | 3 | 0 | 3 |
| CCDC178 | ADAMTSL3 | 0.703987 | 3 | 0 | 3 |
| CCDC178 | PLAC9 | 0.696604 | 3 | 0 | 3 |
| CCDC178 | ZNF385D | 0.696113 | 4 | 0 | 4 |
| CCDC178 | LDB3 | 0.695682 | 3 | 0 | 3 |
| CCDC178 | ANGPTL1 | 0.694911 | 4 | 0 | 4 |
| CCDC178 | CBX7 | 0.692085 | 4 | 0 | 4 |
| CCDC178 | RCAN2 | 0.688725 | 4 | 0 | 4 |
| CCDC178 | KCNB1 | 0.683219 | 3 | 0 | 3 |
| CCDC178 | BHMT2 | 0.683134 | 4 | 0 | 4 |
| CCDC178 | ADAMTSL1 | 0.682619 | 4 | 0 | 4 |
| CCDC178 | PPP1R12B | 0.681831 | 4 | 0 | 4 |
| CCDC178 | KLF9 | 0.67808 | 4 | 0 | 4 |
| CCDC178 | ABI3BP | 0.676764 | 4 | 0 | 4 |
| CCDC178 | FRMD3 | 0.676723 | 4 | 0 | 4 |
| CCDC178 | TGFBR3 | 0.676138 | 4 | 0 | 4 |
| CCDC178 | MYOT | 0.674721 | 4 | 0 | 4 |
| CCDC178 | DSTN | 0.673927 | 3 | 0 | 3 |
| CCDC178 | KCNH2 | 0.672691 | 3 | 0 | 3 |
For details and further investigation, click here
