| Full name: CD55 molecule (Cromer blood group) | Alias Symbol: CR|TC|CROM | ||
| Type: protein-coding gene | Cytoband: 1q32.2 | ||
| Entrez ID: 1604 | HGNC ID: HGNC:2665 | Ensembl Gene: ENSG00000196352 | OMIM ID: 125240 |
| Drug and gene relationship at DGIdb | |||
Expression of CD55:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD55 | 1604 | 1555950_a_at | -0.8175 | 0.4135 | |
| GSE20347 | CD55 | 1604 | 201926_s_at | -1.3363 | 0.0000 | |
| GSE23400 | CD55 | 1604 | 201926_s_at | -1.0134 | 0.0000 | |
| GSE26886 | CD55 | 1604 | 1555950_a_at | -1.0766 | 0.0009 | |
| GSE29001 | CD55 | 1604 | 201925_s_at | -0.6920 | 0.1746 | |
| GSE38129 | CD55 | 1604 | 201925_s_at | -0.2179 | 0.4504 | |
| GSE45670 | CD55 | 1604 | 1555950_a_at | -0.3932 | 0.2289 | |
| GSE53622 | CD55 | 1604 | 27395 | -0.1740 | 0.0669 | |
| GSE53624 | CD55 | 1604 | 27395 | -0.5307 | 0.0000 | |
| GSE63941 | CD55 | 1604 | 1555950_a_at | -0.4655 | 0.5907 | |
| GSE77861 | CD55 | 1604 | 1555950_a_at | -0.3116 | 0.4833 | |
| GSE97050 | CD55 | 1604 | A_24_P188377 | 0.6902 | 0.0866 | |
| SRP007169 | CD55 | 1604 | RNAseq | -1.3707 | 0.0035 | |
| SRP008496 | CD55 | 1604 | RNAseq | -1.5826 | 0.0000 | |
| SRP064894 | CD55 | 1604 | RNAseq | -1.0629 | 0.0000 | |
| SRP133303 | CD55 | 1604 | RNAseq | 0.1315 | 0.6476 | |
| SRP159526 | CD55 | 1604 | RNAseq | -1.1509 | 0.0059 | |
| SRP193095 | CD55 | 1604 | RNAseq | -0.4845 | 0.0928 | |
| SRP219564 | CD55 | 1604 | RNAseq | -0.1567 | 0.7088 | |
| TCGA | CD55 | 1604 | RNAseq | 0.0009 | 0.9904 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by CD55 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD55:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD55 | 1604 | 11 | 0 | 19 | |
| GSE20123 | CD55 | 1604 | 11 | 0 | 19 | |
| GSE43470 | CD55 | 1604 | 8 | 0 | 35 | |
| GSE46452 | CD55 | 1604 | 3 | 1 | 55 | |
| GSE47630 | CD55 | 1604 | 14 | 0 | 26 | |
| GSE54993 | CD55 | 1604 | 0 | 6 | 64 | |
| GSE54994 | CD55 | 1604 | 14 | 0 | 39 | |
| GSE60625 | CD55 | 1604 | 0 | 0 | 11 | |
| GSE74703 | CD55 | 1604 | 8 | 0 | 28 | |
| GSE74704 | CD55 | 1604 | 5 | 0 | 15 | |
| TCGA | CD55 | 1604 | 45 | 3 | 48 |
Total number of gains: 119; Total number of losses: 10; Total Number of normals: 359.
Somatic mutations of CD55:
Generating mutation plots.
Highly correlated genes for CD55:
Showing top 20/316 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD55 | TMEM45B | 0.649864 | 5 | 0 | 5 |
| CD55 | CLIC3 | 0.648518 | 7 | 0 | 7 |
| CD55 | KLK10 | 0.639132 | 5 | 0 | 5 |
| CD55 | KLK11 | 0.632541 | 8 | 0 | 7 |
| CD55 | SPNS2 | 0.62846 | 4 | 0 | 4 |
| CD55 | ATP6V1C2 | 0.626704 | 4 | 0 | 3 |
| CD55 | SERPINB3 | 0.625475 | 7 | 0 | 6 |
| CD55 | PPP1R3C | 0.624097 | 8 | 0 | 6 |
| CD55 | PDLIM2 | 0.621627 | 7 | 0 | 5 |
| CD55 | ITGAD | 0.619149 | 3 | 0 | 3 |
| CD55 | CAMSAP3 | 0.616102 | 4 | 0 | 3 |
| CD55 | NDOR1 | 0.615149 | 5 | 0 | 4 |
| CD55 | FMO2 | 0.614523 | 8 | 0 | 6 |
| CD55 | PRSS3 | 0.614176 | 8 | 0 | 6 |
| CD55 | FUT3 | 0.612226 | 7 | 0 | 4 |
| CD55 | S100P | 0.609281 | 6 | 0 | 4 |
| CD55 | CDC42EP5 | 0.607951 | 3 | 0 | 3 |
| CD55 | SMIM5 | 0.607626 | 5 | 0 | 4 |
| CD55 | TGM1 | 0.606966 | 9 | 0 | 7 |
| CD55 | C15orf62 | 0.606052 | 5 | 0 | 4 |
For details and further investigation, click here
