| Full name: CD6 molecule | Alias Symbol: Tp120 | ||
| Type: protein-coding gene | Cytoband: 11q12.2 | ||
| Entrez ID: 923 | HGNC ID: HGNC:1691 | Ensembl Gene: ENSG00000013725 | OMIM ID: 186720 |
| Drug and gene relationship at DGIdb | |||
Expression of CD6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD6 | 923 | 213958_at | 0.3572 | 0.4827 | |
| GSE20347 | CD6 | 923 | 213958_at | 0.0128 | 0.9331 | |
| GSE23400 | CD6 | 923 | 213958_at | -0.0890 | 0.0471 | |
| GSE26886 | CD6 | 923 | 213958_at | -0.0519 | 0.8053 | |
| GSE29001 | CD6 | 923 | 213958_at | -0.0426 | 0.8107 | |
| GSE38129 | CD6 | 923 | 213958_at | -0.0909 | 0.5351 | |
| GSE45670 | CD6 | 923 | 213958_at | 0.1001 | 0.4724 | |
| GSE53622 | CD6 | 923 | 74125 | -0.7900 | 0.0000 | |
| GSE53624 | CD6 | 923 | 25552 | -0.2852 | 0.0815 | |
| GSE63941 | CD6 | 923 | 213958_at | 0.1456 | 0.3387 | |
| GSE77861 | CD6 | 923 | 213958_at | -0.0285 | 0.8798 | |
| GSE97050 | CD6 | 923 | A_23_P311875 | 0.3791 | 0.1702 | |
| SRP064894 | CD6 | 923 | RNAseq | -0.1133 | 0.7264 | |
| SRP133303 | CD6 | 923 | RNAseq | -0.7401 | 0.0121 | |
| SRP159526 | CD6 | 923 | RNAseq | -1.0188 | 0.2456 | |
| SRP193095 | CD6 | 923 | RNAseq | -0.0725 | 0.7998 | |
| SRP219564 | CD6 | 923 | RNAseq | 0.0084 | 0.9892 | |
| TCGA | CD6 | 923 | RNAseq | 0.1775 | 0.3664 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CD6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD6 | 923 | 2 | 5 | 23 | |
| GSE20123 | CD6 | 923 | 2 | 5 | 23 | |
| GSE43470 | CD6 | 923 | 2 | 6 | 35 | |
| GSE46452 | CD6 | 923 | 8 | 4 | 47 | |
| GSE47630 | CD6 | 923 | 3 | 8 | 29 | |
| GSE54993 | CD6 | 923 | 3 | 0 | 67 | |
| GSE54994 | CD6 | 923 | 5 | 5 | 43 | |
| GSE60625 | CD6 | 923 | 0 | 3 | 8 | |
| GSE74703 | CD6 | 923 | 2 | 3 | 31 | |
| GSE74704 | CD6 | 923 | 2 | 3 | 15 | |
| TCGA | CD6 | 923 | 15 | 10 | 71 |
Total number of gains: 44; Total number of losses: 52; Total Number of normals: 392.
Somatic mutations of CD6:
Generating mutation plots.
Highly correlated genes for CD6:
Showing top 20/405 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD6 | RAB35 | 0.710321 | 3 | 0 | 3 |
| CD6 | RASAL3 | 0.708467 | 6 | 0 | 6 |
| CD6 | ZAP70 | 0.707794 | 10 | 0 | 10 |
| CD6 | FAM98C | 0.705438 | 3 | 0 | 3 |
| CD6 | SLC6A6 | 0.702677 | 3 | 0 | 3 |
| CD6 | RAB3A | 0.700345 | 3 | 0 | 3 |
| CD6 | SNX20 | 0.699442 | 6 | 0 | 5 |
| CD6 | TNFRSF1B | 0.699342 | 6 | 0 | 5 |
| CD6 | CD3E | 0.698257 | 9 | 0 | 8 |
| CD6 | CD3D | 0.696454 | 10 | 0 | 9 |
| CD6 | GIMAP5 | 0.691359 | 4 | 0 | 4 |
| CD6 | PARVG | 0.684578 | 6 | 0 | 5 |
| CD6 | ACAP1 | 0.683081 | 9 | 0 | 7 |
| CD6 | GPR160 | 0.677942 | 3 | 0 | 3 |
| CD6 | PARP15 | 0.667561 | 5 | 0 | 5 |
| CD6 | CD48 | 0.661257 | 8 | 0 | 8 |
| CD6 | TNFSF13 | 0.659446 | 3 | 0 | 3 |
| CD6 | APOL1 | 0.659363 | 3 | 0 | 3 |
| CD6 | IL6R | 0.658075 | 3 | 0 | 3 |
| CD6 | CCR5 | 0.653898 | 9 | 0 | 8 |
For details and further investigation, click here
