| Full name: CDC42 binding protein kinase gamma | Alias Symbol: HSMDPKIN|MRCKgamma|DMPK2|kappa-200 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 55561 | HGNC ID: HGNC:29829 | Ensembl Gene: ENSG00000171219 | OMIM ID: 613991 |
| Drug and gene relationship at DGIdb | |||
Expression of CDC42BPG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDC42BPG | 55561 | 1569044_at | -0.0907 | 0.8195 | |
| GSE26886 | CDC42BPG | 55561 | 1569044_at | 0.2822 | 0.0658 | |
| GSE45670 | CDC42BPG | 55561 | 1569044_at | 0.0187 | 0.9025 | |
| GSE53622 | CDC42BPG | 55561 | 26592 | -0.5835 | 0.0022 | |
| GSE53624 | CDC42BPG | 55561 | 26592 | -0.5424 | 0.0000 | |
| GSE63941 | CDC42BPG | 55561 | 1569044_at | 0.7317 | 0.0003 | |
| GSE77861 | CDC42BPG | 55561 | 1564823_at | -0.0684 | 0.6147 | |
| GSE97050 | CDC42BPG | 55561 | A_33_P3264224 | 0.1904 | 0.4376 | |
| SRP007169 | CDC42BPG | 55561 | RNAseq | -1.0234 | 0.0068 | |
| SRP008496 | CDC42BPG | 55561 | RNAseq | -0.9448 | 0.0030 | |
| SRP064894 | CDC42BPG | 55561 | RNAseq | -0.9628 | 0.0067 | |
| SRP133303 | CDC42BPG | 55561 | RNAseq | -0.9587 | 0.0000 | |
| SRP159526 | CDC42BPG | 55561 | RNAseq | -1.0400 | 0.0056 | |
| SRP193095 | CDC42BPG | 55561 | RNAseq | -0.6513 | 0.0000 | |
| SRP219564 | CDC42BPG | 55561 | RNAseq | -1.1070 | 0.2521 | |
| TCGA | CDC42BPG | 55561 | RNAseq | -0.0201 | 0.8611 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CDC42BPG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDC42BPG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDC42BPG | 55561 | 7 | 6 | 17 | |
| GSE20123 | CDC42BPG | 55561 | 7 | 6 | 17 | |
| GSE43470 | CDC42BPG | 55561 | 1 | 3 | 39 | |
| GSE46452 | CDC42BPG | 55561 | 10 | 4 | 45 | |
| GSE47630 | CDC42BPG | 55561 | 5 | 6 | 29 | |
| GSE54993 | CDC42BPG | 55561 | 3 | 1 | 66 | |
| GSE54994 | CDC42BPG | 55561 | 6 | 5 | 42 | |
| GSE60625 | CDC42BPG | 55561 | 0 | 3 | 8 | |
| GSE74703 | CDC42BPG | 55561 | 1 | 1 | 34 | |
| GSE74704 | CDC42BPG | 55561 | 5 | 4 | 11 | |
| TCGA | CDC42BPG | 55561 | 23 | 7 | 66 |
Total number of gains: 68; Total number of losses: 46; Total Number of normals: 374.
Somatic mutations of CDC42BPG:
Generating mutation plots.
Highly correlated genes for CDC42BPG:
Showing top 20/235 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDC42BPG | APRT | 0.72771 | 3 | 0 | 3 |
| CDC42BPG | GTF3C1 | 0.722589 | 4 | 0 | 4 |
| CDC42BPG | ZNF165 | 0.710061 | 3 | 0 | 3 |
| CDC42BPG | ADAM15 | 0.70763 | 4 | 0 | 4 |
| CDC42BPG | RPS6KA4 | 0.69914 | 3 | 0 | 3 |
| CDC42BPG | CLMN | 0.697655 | 3 | 0 | 3 |
| CDC42BPG | GIT1 | 0.69568 | 3 | 0 | 3 |
| CDC42BPG | RECQL5 | 0.692208 | 5 | 0 | 4 |
| CDC42BPG | USP19 | 0.687874 | 3 | 0 | 3 |
| CDC42BPG | CLN6 | 0.687681 | 3 | 0 | 3 |
| CDC42BPG | ARHGEF16 | 0.687442 | 4 | 0 | 3 |
| CDC42BPG | CLK2 | 0.681572 | 3 | 0 | 3 |
| CDC42BPG | KIAA1522 | 0.679765 | 4 | 0 | 3 |
| CDC42BPG | CLEC16A | 0.672448 | 3 | 0 | 3 |
| CDC42BPG | PAQR4 | 0.668366 | 4 | 0 | 3 |
| CDC42BPG | JUP | 0.661583 | 5 | 0 | 5 |
| CDC42BPG | SLC25A39 | 0.659749 | 5 | 0 | 4 |
| CDC42BPG | USP21 | 0.658166 | 3 | 0 | 3 |
| CDC42BPG | TOM1 | 0.658078 | 4 | 0 | 3 |
| CDC42BPG | SCAMP4 | 0.657934 | 3 | 0 | 3 |
For details and further investigation, click here
