| Full name: carcinoembryonic antigen related cell adhesion molecule 8 | Alias Symbol: CD66b | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 1088 | HGNC ID: HGNC:1820 | Ensembl Gene: ENSG00000124469 | OMIM ID: 615747 |
| Drug and gene relationship at DGIdb | |||
Expression of CEACAM8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CEACAM8 | 1088 | 206676_at | -0.1455 | 0.5791 | |
| GSE20347 | CEACAM8 | 1088 | 206676_at | -0.0980 | 0.0384 | |
| GSE23400 | CEACAM8 | 1088 | 206676_at | -0.1076 | 0.0000 | |
| GSE26886 | CEACAM8 | 1088 | 206676_at | 0.0580 | 0.4594 | |
| GSE29001 | CEACAM8 | 1088 | 206676_at | -0.1344 | 0.1729 | |
| GSE38129 | CEACAM8 | 1088 | 206676_at | -0.1089 | 0.0043 | |
| GSE45670 | CEACAM8 | 1088 | 206676_at | 0.0726 | 0.4300 | |
| GSE53622 | CEACAM8 | 1088 | 11153 | -0.5794 | 0.0018 | |
| GSE53624 | CEACAM8 | 1088 | 11153 | -1.3994 | 0.0000 | |
| GSE63941 | CEACAM8 | 1088 | 206676_at | 0.1120 | 0.4290 | |
| GSE77861 | CEACAM8 | 1088 | 206676_at | -0.1329 | 0.0973 | |
| SRP133303 | CEACAM8 | 1088 | RNAseq | 0.2728 | 0.2245 | |
| TCGA | CEACAM8 | 1088 | RNAseq | 0.9805 | 0.2906 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CEACAM8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CEACAM8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CEACAM8 | 1088 | 5 | 5 | 20 | |
| GSE20123 | CEACAM8 | 1088 | 4 | 4 | 22 | |
| GSE43470 | CEACAM8 | 1088 | 5 | 11 | 27 | |
| GSE46452 | CEACAM8 | 1088 | 47 | 1 | 11 | |
| GSE47630 | CEACAM8 | 1088 | 8 | 6 | 26 | |
| GSE54993 | CEACAM8 | 1088 | 17 | 4 | 49 | |
| GSE54994 | CEACAM8 | 1088 | 7 | 12 | 34 | |
| GSE60625 | CEACAM8 | 1088 | 9 | 0 | 2 | |
| GSE74703 | CEACAM8 | 1088 | 5 | 7 | 24 | |
| GSE74704 | CEACAM8 | 1088 | 4 | 2 | 14 | |
| TCGA | CEACAM8 | 1088 | 13 | 16 | 67 |
Total number of gains: 124; Total number of losses: 68; Total Number of normals: 296.
Somatic mutations of CEACAM8:
Generating mutation plots.
Highly correlated genes for CEACAM8:
Showing top 20/331 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CEACAM8 | TMEM45B | 0.737145 | 3 | 0 | 3 |
| CEACAM8 | CNFN | 0.719907 | 3 | 0 | 3 |
| CEACAM8 | MUC15 | 0.704068 | 3 | 0 | 3 |
| CEACAM8 | XG | 0.694189 | 3 | 0 | 3 |
| CEACAM8 | CERS3 | 0.691643 | 4 | 0 | 4 |
| CEACAM8 | A2ML1 | 0.681934 | 3 | 0 | 3 |
| CEACAM8 | FAM3D | 0.668998 | 3 | 0 | 3 |
| CEACAM8 | CDH20 | 0.65206 | 4 | 0 | 4 |
| CEACAM8 | TTC9 | 0.648986 | 5 | 0 | 5 |
| CEACAM8 | GALNT5 | 0.643007 | 4 | 0 | 3 |
| CEACAM8 | TGM3 | 0.641769 | 6 | 0 | 5 |
| CEACAM8 | RAB10 | 0.631566 | 5 | 0 | 3 |
| CEACAM8 | TTN | 0.631417 | 4 | 0 | 4 |
| CEACAM8 | CAPN14 | 0.631131 | 4 | 0 | 3 |
| CEACAM8 | DENND2C | 0.627587 | 4 | 0 | 3 |
| CEACAM8 | MPP7 | 0.622098 | 4 | 0 | 3 |
| CEACAM8 | ELOVL6 | 0.619607 | 6 | 0 | 5 |
| CEACAM8 | ULK3 | 0.619409 | 4 | 0 | 3 |
| CEACAM8 | DUOXA1 | 0.617329 | 4 | 0 | 3 |
| CEACAM8 | CSTA | 0.614646 | 5 | 0 | 3 |
For details and further investigation, click here
