| Full name: paralemmin 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q31.3 | ||
| Entrez ID: 114299 | HGNC ID: HGNC:15845 | Ensembl Gene: ENSG00000243444 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of PALM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PALM2 | 114299 | 1554640_at | 0.5416 | 0.1500 | |
| GSE26886 | PALM2 | 114299 | 1554640_at | 0.0085 | 0.9642 | |
| GSE45670 | PALM2 | 114299 | 1554640_at | 0.4794 | 0.2371 | |
| GSE63941 | PALM2 | 114299 | 1554640_at | -1.9328 | 0.0011 | |
| GSE77861 | PALM2 | 114299 | 1554640_at | 0.0196 | 0.8778 | |
| GSE97050 | PALM2 | 114299 | A_23_P216579 | 0.6733 | 0.1606 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PALM2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of PALM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PALM2 | 114299 | 5 | 10 | 15 | |
| GSE20123 | PALM2 | 114299 | 5 | 9 | 16 | |
| GSE43470 | PALM2 | 114299 | 4 | 3 | 36 | |
| GSE46452 | PALM2 | 114299 | 6 | 13 | 40 | |
| GSE47630 | PALM2 | 114299 | 3 | 16 | 21 | |
| GSE54993 | PALM2 | 114299 | 3 | 3 | 64 | |
| GSE54994 | PALM2 | 114299 | 9 | 10 | 34 | |
| GSE60625 | PALM2 | 114299 | 0 | 0 | 11 | |
| GSE74703 | PALM2 | 114299 | 4 | 3 | 29 | |
| GSE74704 | PALM2 | 114299 | 2 | 6 | 12 | |
| TCGA | PALM2 | 114299 | 25 | 21 | 50 |
Total number of gains: 66; Total number of losses: 94; Total Number of normals: 328.
Somatic mutations of PALM2:
Generating mutation plots.
Highly correlated genes for PALM2:
Showing top 20/90 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PALM2 | CHST1 | 0.764801 | 3 | 0 | 3 |
| PALM2 | CCT3 | 0.712391 | 3 | 0 | 3 |
| PALM2 | ADAMTS12 | 0.700978 | 4 | 0 | 4 |
| PALM2 | EXT1 | 0.664875 | 4 | 0 | 4 |
| PALM2 | NAGLU | 0.659085 | 3 | 0 | 3 |
| PALM2 | CRELD2 | 0.658523 | 3 | 0 | 3 |
| PALM2 | COL10A1 | 0.656772 | 4 | 0 | 3 |
| PALM2 | CHI3L1 | 0.654454 | 3 | 0 | 3 |
| PALM2 | E2F6 | 0.652138 | 3 | 0 | 3 |
| PALM2 | CTHRC1 | 0.647555 | 5 | 0 | 4 |
| PALM2 | NOX4 | 0.64697 | 5 | 0 | 4 |
| PALM2 | SERPINH1 | 0.642044 | 3 | 0 | 3 |
| PALM2 | PTRH2 | 0.637558 | 3 | 0 | 3 |
| PALM2 | WNT2 | 0.629464 | 4 | 0 | 3 |
| PALM2 | COL18A1 | 0.627645 | 4 | 0 | 3 |
| PALM2 | SH3RF3-AS1 | 0.626545 | 3 | 0 | 3 |
| PALM2 | LOXL2 | 0.625324 | 4 | 0 | 3 |
| PALM2 | EXOC5 | 0.625093 | 3 | 0 | 3 |
| PALM2 | POSTN | 0.619064 | 5 | 0 | 4 |
| PALM2 | ABL2 | 0.617653 | 4 | 0 | 3 |
For details and further investigation, click here
