| Full name: mitochondrial ribosomal protein L19 | Alias Symbol: MRP-L15|RPML15|KIAA0104|RLX1 | ||
| Type: protein-coding gene | Cytoband: 2p12 | ||
| Entrez ID: 9801 | HGNC ID: HGNC:14052 | Ensembl Gene: ENSG00000115364 | OMIM ID: 611832 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPL19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL19 | 9801 | 203465_at | 0.3677 | 0.5800 | |
| GSE20347 | MRPL19 | 9801 | 203465_at | 0.2201 | 0.1390 | |
| GSE23400 | MRPL19 | 9801 | 203465_at | 0.4533 | 0.0000 | |
| GSE26886 | MRPL19 | 9801 | 203465_at | 0.4776 | 0.0256 | |
| GSE29001 | MRPL19 | 9801 | 203465_at | 0.4279 | 0.3968 | |
| GSE38129 | MRPL19 | 9801 | 203465_at | 0.5142 | 0.0004 | |
| GSE45670 | MRPL19 | 9801 | 203465_at | 0.4549 | 0.0023 | |
| GSE53622 | MRPL19 | 9801 | 59564 | 0.2792 | 0.0000 | |
| GSE53624 | MRPL19 | 9801 | 59564 | 0.3229 | 0.0000 | |
| GSE63941 | MRPL19 | 9801 | 203465_at | -0.0943 | 0.8349 | |
| GSE77861 | MRPL19 | 9801 | 203465_at | 0.2219 | 0.1947 | |
| GSE97050 | MRPL19 | 9801 | A_33_P3223088 | -0.8133 | 0.1657 | |
| SRP007169 | MRPL19 | 9801 | RNAseq | 0.6195 | 0.0912 | |
| SRP008496 | MRPL19 | 9801 | RNAseq | 0.4257 | 0.0422 | |
| SRP064894 | MRPL19 | 9801 | RNAseq | 0.0886 | 0.5853 | |
| SRP133303 | MRPL19 | 9801 | RNAseq | 0.3700 | 0.0007 | |
| SRP159526 | MRPL19 | 9801 | RNAseq | 0.5687 | 0.0059 | |
| SRP193095 | MRPL19 | 9801 | RNAseq | 0.0185 | 0.8215 | |
| SRP219564 | MRPL19 | 9801 | RNAseq | 0.1629 | 0.6135 | |
| TCGA | MRPL19 | 9801 | RNAseq | 0.0171 | 0.7148 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPL19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL19 | 9801 | 9 | 3 | 18 | |
| GSE20123 | MRPL19 | 9801 | 9 | 3 | 18 | |
| GSE43470 | MRPL19 | 9801 | 4 | 0 | 39 | |
| GSE46452 | MRPL19 | 9801 | 2 | 3 | 54 | |
| GSE47630 | MRPL19 | 9801 | 7 | 0 | 33 | |
| GSE54993 | MRPL19 | 9801 | 0 | 6 | 64 | |
| GSE54994 | MRPL19 | 9801 | 10 | 0 | 43 | |
| GSE60625 | MRPL19 | 9801 | 0 | 3 | 8 | |
| GSE74703 | MRPL19 | 9801 | 4 | 0 | 32 | |
| GSE74704 | MRPL19 | 9801 | 7 | 1 | 12 | |
| TCGA | MRPL19 | 9801 | 36 | 2 | 58 |
Total number of gains: 88; Total number of losses: 21; Total Number of normals: 379.
Somatic mutations of MRPL19:
Generating mutation plots.
Highly correlated genes for MRPL19:
Showing top 20/1005 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL19 | PPP6R3 | 0.771386 | 3 | 0 | 3 |
| MRPL19 | CMC1 | 0.748169 | 3 | 0 | 3 |
| MRPL19 | RAD17 | 0.742805 | 3 | 0 | 3 |
| MRPL19 | RAB22A | 0.741952 | 4 | 0 | 3 |
| MRPL19 | CLN5 | 0.717891 | 3 | 0 | 3 |
| MRPL19 | ARFGEF2 | 0.716136 | 3 | 0 | 3 |
| MRPL19 | DOCK7 | 0.711998 | 3 | 0 | 3 |
| MRPL19 | EXOC6B | 0.710289 | 4 | 0 | 3 |
| MRPL19 | EME1 | 0.705535 | 3 | 0 | 3 |
| MRPL19 | UBLCP1 | 0.702482 | 4 | 0 | 4 |
| MRPL19 | PUM1 | 0.701839 | 4 | 0 | 4 |
| MRPL19 | CLIP4 | 0.682152 | 3 | 0 | 3 |
| MRPL19 | NDUFS4 | 0.680105 | 3 | 0 | 3 |
| MRPL19 | MRPL42 | 0.677408 | 8 | 0 | 7 |
| MRPL19 | CIAO1 | 0.677326 | 4 | 0 | 4 |
| MRPL19 | GOSR1 | 0.67459 | 3 | 0 | 3 |
| MRPL19 | LANCL2 | 0.670124 | 6 | 0 | 5 |
| MRPL19 | ASF1A | 0.668394 | 4 | 0 | 3 |
| MRPL19 | AGAP1 | 0.664477 | 3 | 0 | 3 |
| MRPL19 | EIF1B | 0.662595 | 4 | 0 | 3 |
For details and further investigation, click here
