CPSF2

 

Full name: cleavage and polyadenylation specific factor 2 Alias Symbol: KIAA1367|CPSF100
Type: protein-coding gene Cytoband: 14q32.12
Entrez ID: 53981 HGNC ID: HGNC:2325 Ensembl Gene: ENSG00000165934 OMIM ID: 606028

 

Expression of CPSF2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CPSF2 53981 225994_at 0.2675 0.7667
GSE26886 CPSF2 53981 225994_at 0.2919 0.2173
GSE45670 CPSF2 53981 225994_at 0.5083 0.0006
GSE53622 CPSF2 53981 49930 -0.1246 0.5724
GSE53624 CPSF2 53981 49930 0.0206 0.9141
GSE63941 CPSF2 53981 225994_at 0.6498 0.1822
GSE77861 CPSF2 53981 225986_x_at 0.0202 0.8671
SRP007169 CPSF2 53981 RNAseq 0.3645 0.2404
SRP008496 CPSF2 53981 RNAseq 0.3138 0.0347
SRP064894 CPSF2 53981 RNAseq 0.4434 0.0096
SRP133303 CPSF2 53981 RNAseq 0.4760 0.0000
SRP159526 CPSF2 53981 RNAseq 0.1354 0.5741
SRP193095 CPSF2 53981 RNAseq 0.1072 0.2264
SRP219564 CPSF2 53981 RNAseq 0.3816 0.2853
TCGA CPSF2 53981 RNAseq 0.0773 0.1026

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by CPSF2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CPSF2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CPSF2 53981 9 5 16
GSE20123 CPSF2 53981 9 4 17
GSE43470 CPSF2 53981 7 3 33
GSE46452 CPSF2 53981 16 3 40
GSE47630 CPSF2 53981 11 8 21
GSE54993 CPSF2 53981 3 8 59
GSE54994 CPSF2 53981 20 4 29
GSE60625 CPSF2 53981 0 2 9
GSE74703 CPSF2 53981 6 3 27
GSE74704 CPSF2 53981 4 3 13
TCGA CPSF2 53981 31 20 45

Total number of gains: 116; Total number of losses: 63; Total Number of normals: 309.  


 

Somatic mutations of CPSF2:

 

Generating mutation plots.

 

Highly correlated genes for CPSF2:

 

Showing top 20/96 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CPSF2CHAC20.692606303
CPSF2LRR10.687815303
CPSF2ACP10.685793303
CPSF2PSMC10.681919404
CPSF2RCOR10.680184303
CPSF2PSEN10.672009303
CPSF2FAM49B0.67169403
CPSF2MGAT20.657023303
CPSF2YY10.655967404
CPSF2HPRT10.654826303
CPSF2CPSF30.647192404
CPSF2PRKDC0.645031303
CPSF2TIMM90.643921303
CPSF2JKAMP0.634436403
CPSF2GINS10.634372303
CPSF2ALKBH10.628147303
CPSF2MATN30.620584303
CPSF2AURKA0.618537303
CPSF2GEMIN60.618514303
CPSF2RDH110.615997604

For details and further investigation, click here