| Full name: cubilin | Alias Symbol: IFCR|gp280 | ||
| Type: protein-coding gene | Cytoband: 10p13 | ||
| Entrez ID: 8029 | HGNC ID: HGNC:2548 | Ensembl Gene: ENSG00000107611 | OMIM ID: 602997 |
| Drug and gene relationship at DGIdb | |||
Expression of CUBN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CUBN | 8029 | 206775_at | -0.0164 | 0.9498 | |
| GSE20347 | CUBN | 8029 | 206775_at | 0.0392 | 0.6509 | |
| GSE23400 | CUBN | 8029 | 206775_at | -0.1338 | 0.0000 | |
| GSE26886 | CUBN | 8029 | 206775_at | -0.0370 | 0.7616 | |
| GSE29001 | CUBN | 8029 | 206775_at | -0.0544 | 0.7070 | |
| GSE38129 | CUBN | 8029 | 206775_at | -0.1364 | 0.0703 | |
| GSE45670 | CUBN | 8029 | 206775_at | -0.0113 | 0.9089 | |
| GSE53622 | CUBN | 8029 | 102689 | -0.6030 | 0.0000 | |
| GSE53624 | CUBN | 8029 | 19356 | 0.2022 | 0.2556 | |
| GSE63941 | CUBN | 8029 | 206775_at | -0.0190 | 0.9266 | |
| GSE77861 | CUBN | 8029 | 206775_at | -0.0202 | 0.8892 | |
| SRP064894 | CUBN | 8029 | RNAseq | 0.0484 | 0.8559 | |
| SRP133303 | CUBN | 8029 | RNAseq | -0.7232 | 0.0004 | |
| SRP159526 | CUBN | 8029 | RNAseq | -0.3790 | 0.3370 | |
| SRP193095 | CUBN | 8029 | RNAseq | 0.0687 | 0.7567 | |
| SRP219564 | CUBN | 8029 | RNAseq | -0.2206 | 0.6511 | |
| TCGA | CUBN | 8029 | RNAseq | -0.6620 | 0.0159 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CUBN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CUBN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CUBN | 8029 | 3 | 8 | 19 | |
| GSE20123 | CUBN | 8029 | 3 | 7 | 20 | |
| GSE43470 | CUBN | 8029 | 3 | 5 | 35 | |
| GSE46452 | CUBN | 8029 | 1 | 14 | 44 | |
| GSE47630 | CUBN | 8029 | 5 | 15 | 20 | |
| GSE54993 | CUBN | 8029 | 10 | 0 | 60 | |
| GSE54994 | CUBN | 8029 | 4 | 9 | 40 | |
| GSE60625 | CUBN | 8029 | 0 | 0 | 11 | |
| GSE74703 | CUBN | 8029 | 2 | 3 | 31 | |
| GSE74704 | CUBN | 8029 | 0 | 6 | 14 | |
| TCGA | CUBN | 8029 | 19 | 26 | 51 |
Total number of gains: 50; Total number of losses: 93; Total Number of normals: 345.
Somatic mutations of CUBN:
Generating mutation plots.
Highly correlated genes for CUBN:
Showing top 20/125 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CUBN | SIRT4 | 0.636496 | 4 | 0 | 4 |
| CUBN | ACSL6 | 0.636019 | 4 | 0 | 3 |
| CUBN | SLC17A3 | 0.632739 | 3 | 0 | 3 |
| CUBN | SLC2A11 | 0.6315 | 3 | 0 | 3 |
| CUBN | ORAI2 | 0.625288 | 3 | 0 | 3 |
| CUBN | SLC22A2 | 0.621729 | 5 | 0 | 4 |
| CUBN | PKDREJ | 0.621108 | 3 | 0 | 3 |
| CUBN | LILRA6 | 0.613986 | 4 | 0 | 3 |
| CUBN | NPHP1 | 0.612393 | 3 | 0 | 3 |
| CUBN | PF4 | 0.609727 | 4 | 0 | 3 |
| CUBN | WNT8B | 0.607715 | 3 | 0 | 3 |
| CUBN | TP53I11 | 0.604268 | 3 | 0 | 3 |
| CUBN | WNT16 | 0.602959 | 3 | 0 | 3 |
| CUBN | ODF1 | 0.594071 | 4 | 0 | 3 |
| CUBN | GP1BA | 0.591457 | 5 | 0 | 3 |
| CUBN | RDH8 | 0.588502 | 3 | 0 | 3 |
| CUBN | CD33 | 0.587846 | 5 | 0 | 4 |
| CUBN | GABRR2 | 0.587075 | 3 | 0 | 3 |
| CUBN | PDCD1 | 0.586941 | 4 | 0 | 3 |
| CUBN | ACTL7A | 0.586353 | 4 | 0 | 3 |
For details and further investigation, click here
