DDX31

 

Full name: DEAD-box helicase 31 Alias Symbol: FLJ13633|FLJ23349|FLJ14578|PPP1R25
Type: protein-coding gene Cytoband: 9q34.13
Entrez ID: 64794 HGNC ID: HGNC:16715 Ensembl Gene: ENSG00000125485 OMIM ID: 616533
Drug and gene relationship at DGIdb

 

Expression of DDX31:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DDX31 64794 219328_at 0.5415 0.1225
GSE20347 DDX31 64794 219328_at 0.2264 0.0385
GSE23400 DDX31 64794 219328_at 0.1150 0.0131
GSE26886 DDX31 64794 219328_at 0.2500 0.0984
GSE29001 DDX31 64794 219328_at 0.4226 0.0302
GSE38129 DDX31 64794 219328_at 0.3361 0.0009
GSE45670 DDX31 64794 219328_at 0.3019 0.0055
GSE53622 DDX31 64794 36369 0.5151 0.0000
GSE53624 DDX31 64794 74484 0.7905 0.0000
GSE63941 DDX31 64794 219328_at 0.5794 0.0328
GSE77861 DDX31 64794 219328_at 0.2683 0.1113
GSE97050 DDX31 64794 A_24_P112377 0.5958 0.1847
SRP007169 DDX31 64794 RNAseq 0.6167 0.1915
SRP008496 DDX31 64794 RNAseq 1.3981 0.0057
SRP064894 DDX31 64794 RNAseq 0.7487 0.0000
SRP133303 DDX31 64794 RNAseq 0.3967 0.0288
SRP159526 DDX31 64794 RNAseq 0.5670 0.1018
SRP193095 DDX31 64794 RNAseq 0.2227 0.0423
SRP219564 DDX31 64794 RNAseq 0.6787 0.1015
TCGA DDX31 64794 RNAseq 0.2175 0.0006

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by DDX31 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of DDX31:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DDX31 64794 5 8 17
GSE20123 DDX31 64794 5 8 17
GSE43470 DDX31 64794 4 7 32
GSE46452 DDX31 64794 6 13 40
GSE47630 DDX31 64794 4 15 21
GSE54993 DDX31 64794 3 3 64
GSE54994 DDX31 64794 12 9 32
GSE60625 DDX31 64794 0 0 11
GSE74703 DDX31 64794 4 5 27
GSE74704 DDX31 64794 3 6 11
TCGA DDX31 64794 28 26 42

Total number of gains: 74; Total number of losses: 100; Total Number of normals: 314.  

 

Somatic mutations of DDX31:

 

Generating mutation plots.

 

Highly correlated genes for DDX31:

 

Showing top 20/987 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DDX31PUS30.723845303
DDX31MARS20.717505303
DDX31PPP1R16A0.709241303
DDX31RBM380.704732303
DDX31DKC10.698505303
DDX31TSHR0.674279303
DDX31CHD70.671628303
DDX31WDR50.668177808
DDX31DPH70.666453705
DDX31HHEX0.664376303
DDX31CCDC1500.662529504
DDX31UTP230.658598505
DDX31TYK20.658446605
DDX31IL31RA0.653913303
DDX31NOP560.651801303
DDX31SIX40.648588504
DDX31DDOST0.647464403
DDX31NLN0.647115403
DDX31NADSYN10.646442303
DDX31OPLAH0.640822303

For details and further investigation, click here