| Full name: DLEC1 cilia and flagella associated protein | Alias Symbol: DLC1|CFAP81 | ||
| Type: protein-coding gene | Cytoband: 3p22.2 | ||
| Entrez ID: 9940 | HGNC ID: HGNC:2899 | Ensembl Gene: ENSG00000008226 | OMIM ID: 604050 |
| Drug and gene relationship at DGIdb | |||
Expression of DLEC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DLEC1 | 9940 | 215085_x_at | 0.0647 | 0.7828 | |
| GSE20347 | DLEC1 | 9940 | 215085_x_at | 0.0694 | 0.4582 | |
| GSE23400 | DLEC1 | 9940 | 215085_x_at | 0.0343 | 0.4027 | |
| GSE26886 | DLEC1 | 9940 | 215085_x_at | 0.1902 | 0.2213 | |
| GSE29001 | DLEC1 | 9940 | 215085_x_at | -0.2206 | 0.1014 | |
| GSE38129 | DLEC1 | 9940 | 215085_x_at | -0.0378 | 0.6778 | |
| GSE45670 | DLEC1 | 9940 | 215085_x_at | 0.0733 | 0.5463 | |
| GSE53622 | DLEC1 | 9940 | 90420 | 0.0873 | 0.5476 | |
| GSE53624 | DLEC1 | 9940 | 93253 | 0.3693 | 0.1244 | |
| GSE63941 | DLEC1 | 9940 | 215085_x_at | 0.5021 | 0.0239 | |
| GSE77861 | DLEC1 | 9940 | 215085_x_at | -0.1014 | 0.4529 | |
| SRP007169 | DLEC1 | 9940 | RNAseq | 0.3598 | 0.6285 | |
| SRP064894 | DLEC1 | 9940 | RNAseq | 0.1363 | 0.6764 | |
| SRP133303 | DLEC1 | 9940 | RNAseq | -0.7967 | 0.0000 | |
| SRP159526 | DLEC1 | 9940 | RNAseq | 1.5789 | 0.0279 | |
| SRP193095 | DLEC1 | 9940 | RNAseq | -0.3618 | 0.0083 | |
| SRP219564 | DLEC1 | 9940 | RNAseq | -0.6582 | 0.1425 | |
| TCGA | DLEC1 | 9940 | RNAseq | 0.2081 | 0.6808 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DLEC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DLEC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DLEC1 | 9940 | 0 | 19 | 11 | |
| GSE20123 | DLEC1 | 9940 | 0 | 19 | 11 | |
| GSE43470 | DLEC1 | 9940 | 0 | 20 | 23 | |
| GSE46452 | DLEC1 | 9940 | 2 | 17 | 40 | |
| GSE47630 | DLEC1 | 9940 | 1 | 25 | 14 | |
| GSE54993 | DLEC1 | 9940 | 6 | 3 | 61 | |
| GSE54994 | DLEC1 | 9940 | 1 | 33 | 19 | |
| GSE60625 | DLEC1 | 9940 | 5 | 0 | 6 | |
| GSE74703 | DLEC1 | 9940 | 0 | 16 | 20 | |
| GSE74704 | DLEC1 | 9940 | 0 | 13 | 7 | |
| TCGA | DLEC1 | 9940 | 1 | 71 | 24 |
Total number of gains: 16; Total number of losses: 236; Total Number of normals: 236.
Somatic mutations of DLEC1:
Generating mutation plots.
Highly correlated genes for DLEC1:
Showing top 20/328 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DLEC1 | C17orf99 | 0.693279 | 3 | 0 | 3 |
| DLEC1 | PHLDB1 | 0.660368 | 4 | 0 | 4 |
| DLEC1 | ACBD4 | 0.656592 | 4 | 0 | 4 |
| DLEC1 | C4BPB | 0.653719 | 3 | 0 | 3 |
| DLEC1 | RNF208 | 0.645681 | 3 | 0 | 3 |
| DLEC1 | CRB1 | 0.641938 | 3 | 0 | 3 |
| DLEC1 | G6PC2 | 0.629952 | 3 | 0 | 3 |
| DLEC1 | ZNF287 | 0.627015 | 3 | 0 | 3 |
| DLEC1 | KCNJ1 | 0.62457 | 3 | 0 | 3 |
| DLEC1 | MMP25 | 0.624372 | 4 | 0 | 3 |
| DLEC1 | ASCL3 | 0.622252 | 4 | 0 | 3 |
| DLEC1 | CEACAM3 | 0.621511 | 4 | 0 | 3 |
| DLEC1 | ITGB7 | 0.615129 | 4 | 0 | 3 |
| DLEC1 | P2RX6 | 0.613579 | 4 | 0 | 4 |
| DLEC1 | MVK | 0.613558 | 5 | 0 | 4 |
| DLEC1 | CRHR2 | 0.613045 | 3 | 0 | 3 |
| DLEC1 | TCL6 | 0.612756 | 5 | 0 | 4 |
| DLEC1 | FREM2 | 0.612748 | 3 | 0 | 3 |
| DLEC1 | UPK3A | 0.612616 | 4 | 0 | 4 |
| DLEC1 | KLK2 | 0.611858 | 4 | 0 | 3 |
For details and further investigation, click here
