| Full name: chromosome 17 open reading frame 99 | Alias Symbol: GLPG464|UNQ464 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 100141515 | HGNC ID: HGNC:34490 | Ensembl Gene: ENSG00000187997 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C17orf99:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C17orf99 | 100141515 | 236981_at | 0.1120 | 0.8163 | |
| GSE26886 | C17orf99 | 100141515 | 236981_at | 0.9118 | 0.0240 | |
| GSE45670 | C17orf99 | 100141515 | 236981_at | 0.5357 | 0.1099 | |
| GSE53622 | C17orf99 | 100141515 | 83253 | 0.6956 | 0.0000 | |
| GSE53624 | C17orf99 | 100141515 | 83253 | 1.2263 | 0.0000 | |
| GSE63941 | C17orf99 | 100141515 | 236981_at | 0.8318 | 0.1554 | |
| GSE77861 | C17orf99 | 100141515 | 236981_at | 0.0095 | 0.9503 | |
| TCGA | C17orf99 | 100141515 | RNAseq | 4.6384 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by C17orf99 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C17orf99:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C17orf99 | 100141515 | 5 | 4 | 21 | |
| GSE20123 | C17orf99 | 100141515 | 5 | 4 | 21 | |
| GSE43470 | C17orf99 | 100141515 | 3 | 4 | 36 | |
| GSE46452 | C17orf99 | 100141515 | 33 | 0 | 26 | |
| GSE47630 | C17orf99 | 100141515 | 8 | 1 | 31 | |
| GSE54993 | C17orf99 | 100141515 | 2 | 5 | 63 | |
| GSE54994 | C17orf99 | 100141515 | 10 | 4 | 39 | |
| GSE60625 | C17orf99 | 100141515 | 6 | 0 | 5 | |
| GSE74703 | C17orf99 | 100141515 | 3 | 2 | 31 | |
| GSE74704 | C17orf99 | 100141515 | 4 | 3 | 13 | |
| TCGA | C17orf99 | 100141515 | 31 | 8 | 57 |
Total number of gains: 110; Total number of losses: 35; Total Number of normals: 343.
Somatic mutations of C17orf99:
Generating mutation plots.
Highly correlated genes for C17orf99:
Showing top 20/50 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C17orf99 | TRPC4 | 0.703318 | 3 | 0 | 3 |
| C17orf99 | DLEC1 | 0.693279 | 3 | 0 | 3 |
| C17orf99 | TEKT2 | 0.670431 | 3 | 0 | 3 |
| C17orf99 | SEMA6B | 0.645577 | 3 | 0 | 3 |
| C17orf99 | CRMP1 | 0.644251 | 3 | 0 | 3 |
| C17orf99 | HCRTR1 | 0.643205 | 3 | 0 | 3 |
| C17orf99 | OSGIN1 | 0.615874 | 3 | 0 | 3 |
| C17orf99 | ANK1 | 0.607002 | 3 | 0 | 3 |
| C17orf99 | B4GALNT1 | 0.605207 | 3 | 0 | 3 |
| C17orf99 | SIGLEC5 | 0.601173 | 3 | 0 | 3 |
| C17orf99 | MYL10 | 0.600949 | 3 | 0 | 3 |
| C17orf99 | SOX1 | 0.591443 | 3 | 0 | 3 |
| C17orf99 | CLSTN3 | 0.58479 | 3 | 0 | 3 |
| C17orf99 | IKBKG | 0.575203 | 5 | 0 | 4 |
| C17orf99 | C16orf74 | 0.568647 | 5 | 0 | 4 |
| C17orf99 | MYOG | 0.567649 | 4 | 0 | 4 |
| C17orf99 | GLI1 | 0.567566 | 5 | 0 | 4 |
| C17orf99 | DERL3 | 0.56356 | 3 | 0 | 3 |
| C17orf99 | TMPRSS3 | 0.562029 | 3 | 0 | 3 |
| C17orf99 | C12orf40 | 0.550923 | 4 | 0 | 3 |
For details and further investigation, click here
