| Full name: spermatogenesis associated 25 | Alias Symbol: dJ337O18.8|TSG23 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 128497 | HGNC ID: HGNC:16158 | Ensembl Gene: ENSG00000149634 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SPATA25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPATA25 | 128497 | 1553752_at | -0.1989 | 0.3211 | |
| GSE26886 | SPATA25 | 128497 | 1553752_at | 0.2444 | 0.0637 | |
| GSE45670 | SPATA25 | 128497 | 1553752_at | -0.0984 | 0.3171 | |
| GSE53622 | SPATA25 | 128497 | 52639 | 0.3732 | 0.0000 | |
| GSE53624 | SPATA25 | 128497 | 52639 | 0.4104 | 0.0000 | |
| GSE63941 | SPATA25 | 128497 | 1553752_at | 0.0328 | 0.8527 | |
| GSE77861 | SPATA25 | 128497 | 1553752_at | -0.2992 | 0.0478 | |
| SRP133303 | SPATA25 | 128497 | RNAseq | -0.3507 | 0.2218 | |
| SRP159526 | SPATA25 | 128497 | RNAseq | 0.3499 | 0.5444 | |
| SRP219564 | SPATA25 | 128497 | RNAseq | -0.1482 | 0.7854 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPATA25 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SPATA25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPATA25 | 128497 | 14 | 1 | 15 | |
| GSE20123 | SPATA25 | 128497 | 14 | 1 | 15 | |
| GSE43470 | SPATA25 | 128497 | 12 | 1 | 30 | |
| GSE46452 | SPATA25 | 128497 | 29 | 0 | 30 | |
| GSE47630 | SPATA25 | 128497 | 24 | 1 | 15 | |
| GSE54993 | SPATA25 | 128497 | 0 | 17 | 53 | |
| GSE54994 | SPATA25 | 128497 | 25 | 0 | 28 | |
| GSE60625 | SPATA25 | 128497 | 0 | 0 | 11 | |
| GSE74703 | SPATA25 | 128497 | 10 | 1 | 25 | |
| GSE74704 | SPATA25 | 128497 | 10 | 0 | 10 | |
| TCGA | SPATA25 | 128497 | 46 | 3 | 47 |
Total number of gains: 184; Total number of losses: 25; Total Number of normals: 279.
Somatic mutations of SPATA25:
Generating mutation plots.
Highly correlated genes for SPATA25:
Showing top 20/84 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPATA25 | HTR1E | 0.686176 | 3 | 0 | 3 |
| SPATA25 | INSL3 | 0.67656 | 3 | 0 | 3 |
| SPATA25 | APOB | 0.667682 | 3 | 0 | 3 |
| SPATA25 | DNAI2 | 0.662953 | 3 | 0 | 3 |
| SPATA25 | MAT1A | 0.653265 | 3 | 0 | 3 |
| SPATA25 | CLDND2 | 0.651378 | 3 | 0 | 3 |
| SPATA25 | ITIH4 | 0.646485 | 3 | 0 | 3 |
| SPATA25 | MUC2 | 0.645461 | 3 | 0 | 3 |
| SPATA25 | CCDC36 | 0.635251 | 3 | 0 | 3 |
| SPATA25 | COL18A1-AS1 | 0.634955 | 3 | 0 | 3 |
| SPATA25 | TMEM232 | 0.633148 | 3 | 0 | 3 |
| SPATA25 | PRM2 | 0.63121 | 3 | 0 | 3 |
| SPATA25 | HMCN2 | 0.629056 | 4 | 0 | 3 |
| SPATA25 | GBX2 | 0.627005 | 3 | 0 | 3 |
| SPATA25 | CCDC116 | 0.625098 | 3 | 0 | 3 |
| SPATA25 | ST3GAL3 | 0.624639 | 3 | 0 | 3 |
| SPATA25 | ABCC8 | 0.624571 | 3 | 0 | 3 |
| SPATA25 | ASPDH | 0.620697 | 3 | 0 | 3 |
| SPATA25 | CDC42BPG | 0.619224 | 3 | 0 | 3 |
| SPATA25 | ISOC2 | 0.617481 | 3 | 0 | 3 |
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