| Full name: NADPH oxidase 3 | Alias Symbol: GP91-3 | ||
| Type: protein-coding gene | Cytoband: 6q25.3 | ||
| Entrez ID: 50508 | HGNC ID: HGNC:7890 | Ensembl Gene: ENSG00000074771 | OMIM ID: 607105 |
NOX3 involved pathways:
Expression of NOX3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOX3 | 50508 | 221089_at | -0.0298 | 0.9162 | |
| GSE20347 | NOX3 | 50508 | 221089_at | -0.0921 | 0.1175 | |
| GSE23400 | NOX3 | 50508 | 221089_at | -0.1160 | 0.0000 | |
| GSE26886 | NOX3 | 50508 | 221089_at | 0.0810 | 0.3726 | |
| GSE29001 | NOX3 | 50508 | 221089_at | -0.1919 | 0.2058 | |
| GSE38129 | NOX3 | 50508 | 221089_at | -0.1015 | 0.0336 | |
| GSE45670 | NOX3 | 50508 | 221089_at | -0.0414 | 0.6435 | |
| GSE53622 | NOX3 | 50508 | 118480 | 0.3131 | 0.0098 | |
| GSE53624 | NOX3 | 50508 | 118480 | 0.1704 | 0.0228 | |
| GSE63941 | NOX3 | 50508 | 221089_at | 0.0236 | 0.8791 | |
| GSE77861 | NOX3 | 50508 | 221089_at | -0.0590 | 0.5209 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NOX3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOX3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOX3 | 50508 | 1 | 4 | 25 | |
| GSE20123 | NOX3 | 50508 | 1 | 3 | 26 | |
| GSE43470 | NOX3 | 50508 | 4 | 0 | 39 | |
| GSE46452 | NOX3 | 50508 | 3 | 10 | 46 | |
| GSE47630 | NOX3 | 50508 | 9 | 4 | 27 | |
| GSE54993 | NOX3 | 50508 | 3 | 2 | 65 | |
| GSE54994 | NOX3 | 50508 | 8 | 8 | 37 | |
| GSE60625 | NOX3 | 50508 | 0 | 1 | 10 | |
| GSE74703 | NOX3 | 50508 | 4 | 0 | 32 | |
| GSE74704 | NOX3 | 50508 | 0 | 1 | 19 | |
| TCGA | NOX3 | 50508 | 12 | 21 | 63 |
Total number of gains: 45; Total number of losses: 54; Total Number of normals: 389.
Somatic mutations of NOX3:
Generating mutation plots.
Highly correlated genes for NOX3:
Showing top 20/287 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOX3 | DNAI2 | 0.694721 | 3 | 0 | 3 |
| NOX3 | LTK | 0.651609 | 3 | 0 | 3 |
| NOX3 | IFNA17 | 0.643892 | 3 | 0 | 3 |
| NOX3 | MC5R | 0.640618 | 3 | 0 | 3 |
| NOX3 | SRPK3 | 0.636469 | 3 | 0 | 3 |
| NOX3 | CAMK4 | 0.634749 | 3 | 0 | 3 |
| NOX3 | SPACA1 | 0.633993 | 4 | 0 | 3 |
| NOX3 | PRPH2 | 0.631504 | 3 | 0 | 3 |
| NOX3 | PSG6 | 0.629246 | 5 | 0 | 3 |
| NOX3 | GDF5 | 0.624771 | 4 | 0 | 3 |
| NOX3 | CNTFR | 0.623582 | 4 | 0 | 3 |
| NOX3 | PCSK2 | 0.620249 | 3 | 0 | 3 |
| NOX3 | KCNJ5 | 0.620136 | 3 | 0 | 3 |
| NOX3 | RNF123 | 0.620134 | 5 | 0 | 3 |
| NOX3 | CRTC1 | 0.619266 | 4 | 0 | 3 |
| NOX3 | XPNPEP2 | 0.616868 | 4 | 0 | 3 |
| NOX3 | NR6A1 | 0.616517 | 6 | 0 | 5 |
| NOX3 | HSD3B2 | 0.61244 | 4 | 0 | 3 |
| NOX3 | CCL27 | 0.611442 | 4 | 0 | 4 |
| NOX3 | HRC | 0.61083 | 4 | 0 | 3 |
For details and further investigation, click here
