| Full name: DnaJ heat shock protein family (Hsp40) member C6 | Alias Symbol: KIAA0473|PARK19 | ||
| Type: protein-coding gene | Cytoband: 1p31.3 | ||
| Entrez ID: 9829 | HGNC ID: HGNC:15469 | Ensembl Gene: ENSG00000116675 | OMIM ID: 608375 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAJC6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJC6 | 9829 | 204720_s_at | 0.8435 | 0.4419 | |
| GSE20347 | DNAJC6 | 9829 | 204720_s_at | 0.5249 | 0.0126 | |
| GSE23400 | DNAJC6 | 9829 | 204720_s_at | 0.0710 | 0.0651 | |
| GSE26886 | DNAJC6 | 9829 | 204720_s_at | 1.1343 | 0.0016 | |
| GSE29001 | DNAJC6 | 9829 | 204720_s_at | 0.4195 | 0.0984 | |
| GSE38129 | DNAJC6 | 9829 | 204720_s_at | 0.3818 | 0.2032 | |
| GSE45670 | DNAJC6 | 9829 | 204720_s_at | 0.4423 | 0.4152 | |
| GSE53622 | DNAJC6 | 9829 | 154308 | 0.1779 | 0.4089 | |
| GSE53624 | DNAJC6 | 9829 | 154308 | 0.7172 | 0.0000 | |
| GSE63941 | DNAJC6 | 9829 | 204720_s_at | 0.7132 | 0.6267 | |
| GSE77861 | DNAJC6 | 9829 | 204721_s_at | -0.0558 | 0.5012 | |
| GSE97050 | DNAJC6 | 9829 | A_33_P3216714 | 0.1280 | 0.7690 | |
| SRP007169 | DNAJC6 | 9829 | RNAseq | 2.3812 | 0.0164 | |
| SRP133303 | DNAJC6 | 9829 | RNAseq | 0.3864 | 0.1188 | |
| SRP159526 | DNAJC6 | 9829 | RNAseq | 0.8842 | 0.1435 | |
| SRP219564 | DNAJC6 | 9829 | RNAseq | 0.9723 | 0.0798 | |
| TCGA | DNAJC6 | 9829 | RNAseq | -1.1103 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by DNAJC6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJC6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJC6 | 9829 | 2 | 6 | 22 | |
| GSE20123 | DNAJC6 | 9829 | 2 | 5 | 23 | |
| GSE43470 | DNAJC6 | 9829 | 4 | 4 | 35 | |
| GSE46452 | DNAJC6 | 9829 | 0 | 1 | 58 | |
| GSE47630 | DNAJC6 | 9829 | 8 | 5 | 27 | |
| GSE54993 | DNAJC6 | 9829 | 0 | 0 | 70 | |
| GSE54994 | DNAJC6 | 9829 | 6 | 4 | 43 | |
| GSE60625 | DNAJC6 | 9829 | 0 | 0 | 11 | |
| GSE74703 | DNAJC6 | 9829 | 3 | 3 | 30 | |
| GSE74704 | DNAJC6 | 9829 | 1 | 2 | 17 | |
| TCGA | DNAJC6 | 9829 | 9 | 21 | 66 |
Total number of gains: 35; Total number of losses: 51; Total Number of normals: 402.
Somatic mutations of DNAJC6:
Generating mutation plots.
Highly correlated genes for DNAJC6:
Showing top 20/168 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJC6 | C20orf96 | 0.698529 | 3 | 0 | 3 |
| DNAJC6 | NPNT | 0.691188 | 3 | 0 | 3 |
| DNAJC6 | GLS | 0.641076 | 4 | 0 | 4 |
| DNAJC6 | SLC16A4 | 0.63125 | 3 | 0 | 3 |
| DNAJC6 | ROMO1 | 0.621653 | 3 | 0 | 3 |
| DNAJC6 | G0S2 | 0.620903 | 6 | 0 | 4 |
| DNAJC6 | SGTB | 0.618801 | 4 | 0 | 3 |
| DNAJC6 | BRCA2 | 0.617267 | 4 | 0 | 3 |
| DNAJC6 | TUBB2B | 0.600194 | 3 | 0 | 3 |
| DNAJC6 | EIF5A2 | 0.59682 | 8 | 0 | 7 |
| DNAJC6 | AEBP1 | 0.594233 | 5 | 0 | 3 |
| DNAJC6 | FTO | 0.593907 | 3 | 0 | 3 |
| DNAJC6 | ZZZ3 | 0.592725 | 3 | 0 | 3 |
| DNAJC6 | AATK | 0.592716 | 4 | 0 | 3 |
| DNAJC6 | CPNE2 | 0.591588 | 3 | 0 | 3 |
| DNAJC6 | NRSN2 | 0.589681 | 4 | 0 | 3 |
| DNAJC6 | ISLR | 0.588943 | 4 | 0 | 3 |
| DNAJC6 | PDGFRL | 0.587594 | 4 | 0 | 3 |
| DNAJC6 | SPATA5 | 0.583378 | 3 | 0 | 3 |
| DNAJC6 | CLIC2 | 0.582551 | 4 | 0 | 3 |
For details and further investigation, click here
