| Full name: docking protein 5 | Alias Symbol: dJ805C22.1 | ||
| Type: protein-coding gene | Cytoband: 20q13.2 | ||
| Entrez ID: 55816 | HGNC ID: HGNC:16173 | Ensembl Gene: ENSG00000101134 | OMIM ID: 608334 |
| Drug and gene relationship at DGIdb | |||
Expression of DOK5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DOK5 | 55816 | 214844_s_at | -0.1265 | 0.8426 | |
| GSE20347 | DOK5 | 55816 | 214844_s_at | 0.1240 | 0.1852 | |
| GSE23400 | DOK5 | 55816 | 214844_s_at | 0.0069 | 0.9093 | |
| GSE26886 | DOK5 | 55816 | 1554863_s_at | -0.1038 | 0.4341 | |
| GSE29001 | DOK5 | 55816 | 214844_s_at | 0.0397 | 0.8695 | |
| GSE38129 | DOK5 | 55816 | 214844_s_at | 0.0880 | 0.6549 | |
| GSE45670 | DOK5 | 55816 | 1554863_s_at | -0.2339 | 0.0156 | |
| GSE53622 | DOK5 | 55816 | 85238 | 0.5260 | 0.0047 | |
| GSE53624 | DOK5 | 55816 | 85238 | 0.4922 | 0.0220 | |
| GSE63941 | DOK5 | 55816 | 1554863_s_at | -0.9253 | 0.1132 | |
| GSE77861 | DOK5 | 55816 | 1554863_s_at | -0.1671 | 0.0633 | |
| GSE97050 | DOK5 | 55816 | A_23_P40217 | 0.2139 | 0.3096 | |
| SRP133303 | DOK5 | 55816 | RNAseq | 0.3045 | 0.4582 | |
| SRP159526 | DOK5 | 55816 | RNAseq | 1.6800 | 0.0082 | |
| SRP219564 | DOK5 | 55816 | RNAseq | 1.4394 | 0.0761 | |
| TCGA | DOK5 | 55816 | RNAseq | -0.3574 | 0.2976 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DOK5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DOK5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DOK5 | 55816 | 15 | 1 | 14 | |
| GSE20123 | DOK5 | 55816 | 17 | 1 | 12 | |
| GSE43470 | DOK5 | 55816 | 14 | 0 | 29 | |
| GSE46452 | DOK5 | 55816 | 29 | 0 | 30 | |
| GSE47630 | DOK5 | 55816 | 24 | 1 | 15 | |
| GSE54993 | DOK5 | 55816 | 0 | 17 | 53 | |
| GSE54994 | DOK5 | 55816 | 27 | 0 | 26 | |
| GSE60625 | DOK5 | 55816 | 0 | 0 | 11 | |
| GSE74703 | DOK5 | 55816 | 11 | 0 | 25 | |
| GSE74704 | DOK5 | 55816 | 12 | 0 | 8 | |
| TCGA | DOK5 | 55816 | 46 | 3 | 47 |
Total number of gains: 195; Total number of losses: 23; Total Number of normals: 270.
Somatic mutations of DOK5:
Generating mutation plots.
Highly correlated genes for DOK5:
Showing top 20/641 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DOK5 | NNMT | 0.743134 | 3 | 0 | 3 |
| DOK5 | TAGAP | 0.738854 | 3 | 0 | 3 |
| DOK5 | RBP5 | 0.733407 | 3 | 0 | 3 |
| DOK5 | NLRP10 | 0.730313 | 3 | 0 | 3 |
| DOK5 | HSD11B1 | 0.716187 | 8 | 0 | 7 |
| DOK5 | S1PR1 | 0.705974 | 6 | 0 | 6 |
| DOK5 | MRGPRF | 0.703843 | 4 | 0 | 4 |
| DOK5 | GIMAP6 | 0.700312 | 5 | 0 | 5 |
| DOK5 | FCGR3A | 0.700018 | 3 | 0 | 3 |
| DOK5 | GPC6 | 0.694639 | 7 | 0 | 7 |
| DOK5 | SPATA9 | 0.694531 | 4 | 0 | 3 |
| DOK5 | KBTBD8 | 0.687746 | 4 | 0 | 4 |
| DOK5 | MAP4 | 0.684808 | 4 | 0 | 3 |
| DOK5 | RARRES2 | 0.682991 | 6 | 0 | 6 |
| DOK5 | RASGRP2 | 0.682693 | 4 | 0 | 3 |
| DOK5 | LILRB2 | 0.682259 | 4 | 0 | 4 |
| DOK5 | TRIM8 | 0.680594 | 4 | 0 | 3 |
| DOK5 | OLFML3 | 0.67833 | 7 | 0 | 7 |
| DOK5 | ARHGAP31 | 0.673922 | 6 | 0 | 5 |
| DOK5 | PDGFRL | 0.673356 | 7 | 0 | 6 |
For details and further investigation, click here
