| Full name: NLR family pyrin domain containing 10 | Alias Symbol: NOD8|PAN5|Pynod|CLR11.1 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 338322 | HGNC ID: HGNC:21464 | Ensembl Gene: ENSG00000182261 | OMIM ID: 609662 |
| Drug and gene relationship at DGIdb | |||
Expression of NLRP10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NLRP10 | 338322 | 1553534_at | -0.0023 | 0.9942 | |
| GSE26886 | NLRP10 | 338322 | 1553534_at | 0.1134 | 0.2607 | |
| GSE45670 | NLRP10 | 338322 | 1553534_at | 0.0174 | 0.8512 | |
| GSE53622 | NLRP10 | 338322 | 108783 | 0.8652 | 0.0071 | |
| GSE53624 | NLRP10 | 338322 | 108783 | 1.0931 | 0.0000 | |
| GSE63941 | NLRP10 | 338322 | 1553534_at | -0.0561 | 0.7893 | |
| GSE77861 | NLRP10 | 338322 | 1553534_at | -0.0232 | 0.8308 | |
| GSE97050 | NLRP10 | 338322 | A_23_P403488 | 0.3496 | 0.1955 | |
| SRP007169 | NLRP10 | 338322 | RNAseq | -1.3008 | 0.1024 | |
| SRP064894 | NLRP10 | 338322 | RNAseq | -0.5059 | 0.1603 | |
| SRP133303 | NLRP10 | 338322 | RNAseq | 0.1374 | 0.3640 | |
| SRP159526 | NLRP10 | 338322 | RNAseq | 0.9067 | 0.1458 | |
| SRP193095 | NLRP10 | 338322 | RNAseq | 0.2124 | 0.1676 | |
| SRP219564 | NLRP10 | 338322 | RNAseq | 1.0302 | 0.1533 | |
| TCGA | NLRP10 | 338322 | RNAseq | 2.5843 | 0.0034 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NLRP10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NLRP10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NLRP10 | 338322 | 0 | 11 | 19 | |
| GSE20123 | NLRP10 | 338322 | 0 | 11 | 19 | |
| GSE43470 | NLRP10 | 338322 | 1 | 7 | 35 | |
| GSE46452 | NLRP10 | 338322 | 7 | 5 | 47 | |
| GSE47630 | NLRP10 | 338322 | 2 | 12 | 26 | |
| GSE54993 | NLRP10 | 338322 | 3 | 1 | 66 | |
| GSE54994 | NLRP10 | 338322 | 2 | 12 | 39 | |
| GSE60625 | NLRP10 | 338322 | 0 | 0 | 11 | |
| GSE74703 | NLRP10 | 338322 | 1 | 5 | 30 | |
| GSE74704 | NLRP10 | 338322 | 0 | 9 | 11 | |
| TCGA | NLRP10 | 338322 | 9 | 36 | 51 |
Total number of gains: 25; Total number of losses: 109; Total Number of normals: 354.
Somatic mutations of NLRP10:
Generating mutation plots.
Highly correlated genes for NLRP10:
Showing top 20/33 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NLRP10 | DOK5 | 0.730313 | 3 | 0 | 3 |
| NLRP10 | CNTNAP1 | 0.707665 | 3 | 0 | 3 |
| NLRP10 | RASA3 | 0.671098 | 3 | 0 | 3 |
| NLRP10 | ZNF804A | 0.667855 | 3 | 0 | 3 |
| NLRP10 | ADAM19 | 0.659195 | 3 | 0 | 3 |
| NLRP10 | NLGN3 | 0.658571 | 3 | 0 | 3 |
| NLRP10 | CLEC4A | 0.654058 | 3 | 0 | 3 |
| NLRP10 | ARHGAP31 | 0.634902 | 3 | 0 | 3 |
| NLRP10 | SECTM1 | 0.633182 | 3 | 0 | 3 |
| NLRP10 | CETP | 0.623939 | 4 | 0 | 3 |
| NLRP10 | HSD11B1 | 0.614423 | 3 | 0 | 3 |
| NLRP10 | CCND3 | 0.609382 | 4 | 0 | 3 |
| NLRP10 | ENG | 0.609225 | 3 | 0 | 3 |
| NLRP10 | TRPM6 | 0.598472 | 3 | 0 | 3 |
| NLRP10 | NECAP2 | 0.597367 | 3 | 0 | 3 |
| NLRP10 | PODN | 0.592212 | 3 | 0 | 3 |
| NLRP10 | TRAF1 | 0.582763 | 3 | 0 | 3 |
| NLRP10 | TRPV2 | 0.578948 | 4 | 0 | 3 |
| NLRP10 | CR1L | 0.577778 | 4 | 0 | 3 |
| NLRP10 | GFRA1 | 0.567293 | 3 | 0 | 3 |
For details and further investigation, click here
