| Full name: dystrobrevin beta | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 1838 | HGNC ID: HGNC:3058 | Ensembl Gene: ENSG00000138101 | OMIM ID: 602415 |
| Drug and gene relationship at DGIdb | |||
Expression of DTNB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DTNB | 1838 | 214253_s_at | 0.3282 | 0.5964 | |
| GSE20347 | DTNB | 1838 | 214253_s_at | 0.0749 | 0.5567 | |
| GSE23400 | DTNB | 1838 | 214253_s_at | -0.0877 | 0.0223 | |
| GSE26886 | DTNB | 1838 | 214253_s_at | 0.6166 | 0.0001 | |
| GSE29001 | DTNB | 1838 | 214253_s_at | 0.0572 | 0.7340 | |
| GSE38129 | DTNB | 1838 | 214253_s_at | 0.0963 | 0.2699 | |
| GSE45670 | DTNB | 1838 | 214253_s_at | 0.1072 | 0.3952 | |
| GSE53622 | DTNB | 1838 | 111103 | 0.5869 | 0.0000 | |
| GSE53624 | DTNB | 1838 | 111103 | 0.4275 | 0.0000 | |
| GSE63941 | DTNB | 1838 | 214253_s_at | 0.3333 | 0.2079 | |
| GSE77861 | DTNB | 1838 | 214253_s_at | -0.0169 | 0.8772 | |
| GSE97050 | DTNB | 1838 | A_24_P216421 | 0.5949 | 0.1984 | |
| SRP007169 | DTNB | 1838 | RNAseq | 0.3519 | 0.5262 | |
| SRP008496 | DTNB | 1838 | RNAseq | 0.7313 | 0.0605 | |
| SRP064894 | DTNB | 1838 | RNAseq | 0.0556 | 0.7890 | |
| SRP133303 | DTNB | 1838 | RNAseq | -0.1928 | 0.2634 | |
| SRP159526 | DTNB | 1838 | RNAseq | 1.5288 | 0.0052 | |
| SRP193095 | DTNB | 1838 | RNAseq | 0.3617 | 0.0086 | |
| SRP219564 | DTNB | 1838 | RNAseq | 0.6491 | 0.1730 | |
| TCGA | DTNB | 1838 | RNAseq | 0.0505 | 0.5795 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DTNB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DTNB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DTNB | 1838 | 11 | 2 | 17 | |
| GSE20123 | DTNB | 1838 | 11 | 2 | 17 | |
| GSE43470 | DTNB | 1838 | 3 | 1 | 39 | |
| GSE46452 | DTNB | 1838 | 3 | 4 | 52 | |
| GSE47630 | DTNB | 1838 | 8 | 0 | 32 | |
| GSE54993 | DTNB | 1838 | 0 | 6 | 64 | |
| GSE54994 | DTNB | 1838 | 10 | 0 | 43 | |
| GSE60625 | DTNB | 1838 | 0 | 3 | 8 | |
| GSE74703 | DTNB | 1838 | 3 | 0 | 33 | |
| GSE74704 | DTNB | 1838 | 9 | 1 | 10 | |
| TCGA | DTNB | 1838 | 37 | 3 | 56 |
Total number of gains: 95; Total number of losses: 22; Total Number of normals: 371.
Somatic mutations of DTNB:
Generating mutation plots.
Highly correlated genes for DTNB:
Showing top 20/127 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DTNB | TMC8 | 0.737012 | 3 | 0 | 3 |
| DTNB | CFB | 0.707907 | 3 | 0 | 3 |
| DTNB | SUPT5H | 0.707845 | 3 | 0 | 3 |
| DTNB | KLHDC7B | 0.703667 | 3 | 0 | 3 |
| DTNB | MSLN | 0.700245 | 3 | 0 | 3 |
| DTNB | WDR66 | 0.695582 | 3 | 0 | 3 |
| DTNB | CCDC34 | 0.674231 | 3 | 0 | 3 |
| DTNB | CD22 | 0.643896 | 3 | 0 | 3 |
| DTNB | ZBP1 | 0.639778 | 3 | 0 | 3 |
| DTNB | HAX1 | 0.638271 | 3 | 0 | 3 |
| DTNB | MAP4K1 | 0.63657 | 4 | 0 | 4 |
| DTNB | FBXO17 | 0.635945 | 3 | 0 | 3 |
| DTNB | FBXO24 | 0.62648 | 3 | 0 | 3 |
| DTNB | CCDC102A | 0.621576 | 3 | 0 | 3 |
| DTNB | CD274 | 0.620215 | 3 | 0 | 3 |
| DTNB | TMEM163 | 0.614235 | 3 | 0 | 3 |
| DTNB | PHF21A | 0.611533 | 3 | 0 | 3 |
| DTNB | MICALL2 | 0.611362 | 6 | 0 | 4 |
| DTNB | ACSF3 | 0.602947 | 3 | 0 | 3 |
| DTNB | EPHB2 | 0.5993 | 4 | 0 | 3 |
For details and further investigation, click here
