| Full name: DLG associated protein 5 | Alias Symbol: KIAA0008|DLG1|HURP | ||
| Type: protein-coding gene | Cytoband: 14q22.3 | ||
| Entrez ID: 9787 | HGNC ID: HGNC:16864 | Ensembl Gene: ENSG00000126787 | OMIM ID: 617859 |
| Drug and gene relationship at DGIdb | |||
Expression of DLGAP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DLGAP5 | 9787 | 203764_at | 1.6313 | 0.0821 | |
| GSE20347 | DLGAP5 | 9787 | 203764_at | 1.9527 | 0.0000 | |
| GSE23400 | DLGAP5 | 9787 | 203764_at | 1.5642 | 0.0000 | |
| GSE26886 | DLGAP5 | 9787 | 203764_at | 1.0501 | 0.0758 | |
| GSE29001 | DLGAP5 | 9787 | 203764_at | 1.8921 | 0.0009 | |
| GSE38129 | DLGAP5 | 9787 | 203764_at | 2.4854 | 0.0000 | |
| GSE45670 | DLGAP5 | 9787 | 203764_at | 1.8857 | 0.0000 | |
| GSE53622 | DLGAP5 | 9787 | 10189 | 1.8683 | 0.0000 | |
| GSE53624 | DLGAP5 | 9787 | 10189 | 2.0478 | 0.0000 | |
| GSE63941 | DLGAP5 | 9787 | 203764_at | 3.5183 | 0.0003 | |
| GSE77861 | DLGAP5 | 9787 | 203764_at | 0.9888 | 0.1692 | |
| GSE97050 | DLGAP5 | 9787 | A_23_P88331 | 1.2849 | 0.1453 | |
| SRP007169 | DLGAP5 | 9787 | RNAseq | 1.6230 | 0.0001 | |
| SRP008496 | DLGAP5 | 9787 | RNAseq | 1.2288 | 0.0000 | |
| SRP064894 | DLGAP5 | 9787 | RNAseq | 1.9514 | 0.0000 | |
| SRP133303 | DLGAP5 | 9787 | RNAseq | 1.7113 | 0.0000 | |
| SRP159526 | DLGAP5 | 9787 | RNAseq | 1.0945 | 0.0285 | |
| SRP193095 | DLGAP5 | 9787 | RNAseq | 1.0354 | 0.0000 | |
| SRP219564 | DLGAP5 | 9787 | RNAseq | 1.7956 | 0.0273 | |
| TCGA | DLGAP5 | 9787 | RNAseq | 1.4044 | 0.0000 |
Upregulated datasets: 16; Downregulated datasets: 0.
Survival by DLGAP5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DLGAP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DLGAP5 | 9787 | 8 | 3 | 19 | |
| GSE20123 | DLGAP5 | 9787 | 8 | 3 | 19 | |
| GSE43470 | DLGAP5 | 9787 | 9 | 1 | 33 | |
| GSE46452 | DLGAP5 | 9787 | 16 | 3 | 40 | |
| GSE47630 | DLGAP5 | 9787 | 11 | 10 | 19 | |
| GSE54993 | DLGAP5 | 9787 | 3 | 8 | 59 | |
| GSE54994 | DLGAP5 | 9787 | 19 | 4 | 30 | |
| GSE60625 | DLGAP5 | 9787 | 0 | 2 | 9 | |
| GSE74703 | DLGAP5 | 9787 | 8 | 1 | 27 | |
| GSE74704 | DLGAP5 | 9787 | 3 | 2 | 15 | |
| TCGA | DLGAP5 | 9787 | 32 | 14 | 50 |
Total number of gains: 117; Total number of losses: 51; Total Number of normals: 320.
Somatic mutations of DLGAP5:
Generating mutation plots.
Highly correlated genes for DLGAP5:
Showing top 20/1637 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DLGAP5 | CDKN3 | 0.882248 | 13 | 0 | 13 |
| DLGAP5 | CDK1 | 0.861312 | 12 | 0 | 12 |
| DLGAP5 | CDC20 | 0.860514 | 13 | 0 | 12 |
| DLGAP5 | WDHD1 | 0.859362 | 12 | 0 | 12 |
| DLGAP5 | RACGAP1 | 0.856815 | 10 | 0 | 10 |
| DLGAP5 | BUB1 | 0.853395 | 10 | 0 | 10 |
| DLGAP5 | TPX2 | 0.846687 | 13 | 0 | 13 |
| DLGAP5 | KIF2C | 0.845969 | 13 | 0 | 12 |
| DLGAP5 | CENPF | 0.844933 | 12 | 0 | 12 |
| DLGAP5 | TTK | 0.844864 | 11 | 0 | 11 |
| DLGAP5 | CCNB2 | 0.843536 | 11 | 0 | 11 |
| DLGAP5 | HJURP | 0.840168 | 11 | 0 | 11 |
| DLGAP5 | BUB1B | 0.835701 | 11 | 0 | 10 |
| DLGAP5 | BOP1 | 0.832064 | 3 | 0 | 3 |
| DLGAP5 | KIF20A | 0.830361 | 13 | 0 | 13 |
| DLGAP5 | CKS1B | 0.825125 | 12 | 0 | 12 |
| DLGAP5 | FOXM1 | 0.825107 | 12 | 0 | 12 |
| DLGAP5 | CEP55 | 0.824917 | 13 | 0 | 12 |
| DLGAP5 | KIF4A | 0.821577 | 13 | 0 | 12 |
| DLGAP5 | RAD51AP1 | 0.818789 | 13 | 0 | 13 |
For details and further investigation, click here
