| Full name: zinc finger protein 385A | Alias Symbol: DKFZp586G1122|Hzf|ZFP385 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 25946 | HGNC ID: HGNC:17521 | Ensembl Gene: ENSG00000161642 | OMIM ID: 609124 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZNF385A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF385A | 25946 | 226111_s_at | 0.4672 | 0.4559 | |
| GSE26886 | ZNF385A | 25946 | 226111_s_at | 0.3478 | 0.0950 | |
| GSE45670 | ZNF385A | 25946 | 226111_s_at | 0.1790 | 0.1525 | |
| GSE53622 | ZNF385A | 25946 | 9584 | -0.0105 | 0.9461 | |
| GSE53624 | ZNF385A | 25946 | 9584 | 0.0560 | 0.4490 | |
| GSE63941 | ZNF385A | 25946 | 226111_s_at | 1.1075 | 0.0015 | |
| GSE77861 | ZNF385A | 25946 | 226111_s_at | -0.0156 | 0.9653 | |
| GSE97050 | ZNF385A | 25946 | A_24_P403734 | 0.1733 | 0.6271 | |
| SRP007169 | ZNF385A | 25946 | RNAseq | 0.0226 | 0.9496 | |
| SRP008496 | ZNF385A | 25946 | RNAseq | -0.5587 | 0.0678 | |
| SRP064894 | ZNF385A | 25946 | RNAseq | -0.1206 | 0.6183 | |
| SRP133303 | ZNF385A | 25946 | RNAseq | 0.0097 | 0.9690 | |
| SRP159526 | ZNF385A | 25946 | RNAseq | -0.6363 | 0.0402 | |
| SRP193095 | ZNF385A | 25946 | RNAseq | 0.1811 | 0.5590 | |
| SRP219564 | ZNF385A | 25946 | RNAseq | -0.0776 | 0.8687 | |
| TCGA | ZNF385A | 25946 | RNAseq | 0.5242 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZNF385A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF385A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF385A | 25946 | 4 | 1 | 25 | |
| GSE20123 | ZNF385A | 25946 | 4 | 1 | 25 | |
| GSE43470 | ZNF385A | 25946 | 3 | 0 | 40 | |
| GSE46452 | ZNF385A | 25946 | 7 | 1 | 51 | |
| GSE47630 | ZNF385A | 25946 | 10 | 2 | 28 | |
| GSE54993 | ZNF385A | 25946 | 0 | 5 | 65 | |
| GSE54994 | ZNF385A | 25946 | 4 | 1 | 48 | |
| GSE60625 | ZNF385A | 25946 | 0 | 0 | 11 | |
| GSE74703 | ZNF385A | 25946 | 3 | 0 | 33 | |
| GSE74704 | ZNF385A | 25946 | 3 | 1 | 16 | |
| TCGA | ZNF385A | 25946 | 15 | 11 | 70 |
Total number of gains: 53; Total number of losses: 23; Total Number of normals: 412.
Somatic mutations of ZNF385A:
Generating mutation plots.
Highly correlated genes for ZNF385A:
Showing top 20/289 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF385A | STK11 | 0.701191 | 3 | 0 | 3 |
| ZNF385A | ATP6V1F | 0.694594 | 3 | 0 | 3 |
| ZNF385A | EGR4 | 0.691308 | 3 | 0 | 3 |
| ZNF385A | PTCH2 | 0.686975 | 3 | 0 | 3 |
| ZNF385A | GNB3 | 0.678903 | 3 | 0 | 3 |
| ZNF385A | EDARADD | 0.67477 | 4 | 0 | 3 |
| ZNF385A | LRCH4 | 0.672208 | 3 | 0 | 3 |
| ZNF385A | IPO13 | 0.669241 | 4 | 0 | 3 |
| ZNF385A | CROCC | 0.669157 | 3 | 0 | 3 |
| ZNF385A | MRPS2 | 0.665047 | 3 | 0 | 3 |
| ZNF385A | TAF5L | 0.664654 | 3 | 0 | 3 |
| ZNF385A | CORO7 | 0.65893 | 3 | 0 | 3 |
| ZNF385A | PRKCZ | 0.655371 | 3 | 0 | 3 |
| ZNF385A | ARHGDIA | 0.655017 | 5 | 0 | 3 |
| ZNF385A | PRRG4 | 0.65316 | 3 | 0 | 3 |
| ZNF385A | MAT1A | 0.652206 | 4 | 0 | 3 |
| ZNF385A | DTX2 | 0.650999 | 4 | 0 | 4 |
| ZNF385A | GM2A | 0.650466 | 4 | 0 | 3 |
| ZNF385A | STARD3 | 0.649313 | 3 | 0 | 3 |
| ZNF385A | REM2 | 0.648954 | 3 | 0 | 3 |
For details and further investigation, click here
