| Full name: EH domain containing 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 30844 | HGNC ID: HGNC:3245 | Ensembl Gene: ENSG00000103966 | OMIM ID: 605892 |
| Drug and gene relationship at DGIdb | |||
Expression of EHD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EHD4 | 30844 | 209536_s_at | 0.0782 | 0.9336 | |
| GSE20347 | EHD4 | 30844 | 209536_s_at | -0.0751 | 0.7630 | |
| GSE23400 | EHD4 | 30844 | 209536_s_at | -0.2255 | 0.0016 | |
| GSE26886 | EHD4 | 30844 | 209536_s_at | -1.0985 | 0.0004 | |
| GSE29001 | EHD4 | 30844 | 209536_s_at | -0.3707 | 0.0933 | |
| GSE38129 | EHD4 | 30844 | 209536_s_at | -0.0060 | 0.9780 | |
| GSE45670 | EHD4 | 30844 | 209536_s_at | 0.1957 | 0.3030 | |
| GSE53622 | EHD4 | 30844 | 72451 | 0.1151 | 0.3039 | |
| GSE53624 | EHD4 | 30844 | 72451 | 0.0281 | 0.8809 | |
| GSE63941 | EHD4 | 30844 | 209536_s_at | 0.8815 | 0.0633 | |
| GSE77861 | EHD4 | 30844 | 209536_s_at | -0.0568 | 0.8087 | |
| GSE97050 | EHD4 | 30844 | A_23_P163458 | 0.3967 | 0.3271 | |
| SRP007169 | EHD4 | 30844 | RNAseq | 0.0897 | 0.8767 | |
| SRP008496 | EHD4 | 30844 | RNAseq | 0.0372 | 0.9074 | |
| SRP064894 | EHD4 | 30844 | RNAseq | 0.0419 | 0.8114 | |
| SRP133303 | EHD4 | 30844 | RNAseq | 0.1373 | 0.4267 | |
| SRP159526 | EHD4 | 30844 | RNAseq | -0.5477 | 0.2367 | |
| SRP193095 | EHD4 | 30844 | RNAseq | 0.0739 | 0.6209 | |
| SRP219564 | EHD4 | 30844 | RNAseq | -0.5057 | 0.2433 | |
| TCGA | EHD4 | 30844 | RNAseq | 0.0939 | 0.1157 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by EHD4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EHD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EHD4 | 30844 | 4 | 5 | 21 | |
| GSE20123 | EHD4 | 30844 | 4 | 5 | 21 | |
| GSE43470 | EHD4 | 30844 | 4 | 5 | 34 | |
| GSE46452 | EHD4 | 30844 | 3 | 7 | 49 | |
| GSE47630 | EHD4 | 30844 | 8 | 11 | 21 | |
| GSE54993 | EHD4 | 30844 | 4 | 6 | 60 | |
| GSE54994 | EHD4 | 30844 | 5 | 7 | 41 | |
| GSE60625 | EHD4 | 30844 | 4 | 0 | 7 | |
| GSE74703 | EHD4 | 30844 | 4 | 4 | 28 | |
| GSE74704 | EHD4 | 30844 | 3 | 3 | 14 | |
| TCGA | EHD4 | 30844 | 11 | 17 | 68 |
Total number of gains: 54; Total number of losses: 70; Total Number of normals: 364.
Somatic mutations of EHD4:
Generating mutation plots.
Highly correlated genes for EHD4:
Showing top 20/219 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EHD4 | FAM83A | 0.653039 | 6 | 0 | 5 |
| EHD4 | RBKS | 0.65242 | 3 | 0 | 3 |
| EHD4 | TMEM117 | 0.641624 | 3 | 0 | 3 |
| EHD4 | BCL10 | 0.635876 | 5 | 0 | 4 |
| EHD4 | JAG1 | 0.632376 | 3 | 0 | 3 |
| EHD4 | TGFA | 0.627398 | 5 | 0 | 4 |
| EHD4 | PRCP | 0.626759 | 3 | 0 | 3 |
| EHD4 | IL36G | 0.623312 | 4 | 0 | 3 |
| EHD4 | SLC12A6 | 0.620381 | 4 | 0 | 3 |
| EHD4 | CDCP1 | 0.619561 | 8 | 0 | 7 |
| EHD4 | RAB11A | 0.61547 | 4 | 0 | 4 |
| EHD4 | WASF2 | 0.611129 | 3 | 0 | 3 |
| EHD4 | RARG | 0.610049 | 3 | 0 | 3 |
| EHD4 | RASGRP1 | 0.605125 | 4 | 0 | 3 |
| EHD4 | PDCD6IP | 0.595646 | 5 | 0 | 5 |
| EHD4 | MYO1E | 0.594574 | 10 | 0 | 6 |
| EHD4 | HPSE | 0.593859 | 6 | 0 | 5 |
| EHD4 | PGM3 | 0.592782 | 4 | 0 | 3 |
| EHD4 | KLK5 | 0.592208 | 5 | 0 | 4 |
| EHD4 | SDC1 | 0.589848 | 7 | 0 | 6 |
For details and further investigation, click here
