| Full name: prolylcarboxypeptidase | Alias Symbol: PCP|HUMPCP | ||
| Type: protein-coding gene | Cytoband: 11q14 | ||
| Entrez ID: 5547 | HGNC ID: HGNC:9344 | Ensembl Gene: ENSG00000137509 | OMIM ID: 176785 |
| Drug and gene relationship at DGIdb | |||
Expression of PRCP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRCP | 5547 | 201494_at | -0.1463 | 0.8684 | |
| GSE20347 | PRCP | 5547 | 201494_at | -0.5079 | 0.0030 | |
| GSE23400 | PRCP | 5547 | 201494_at | -0.0972 | 0.1446 | |
| GSE26886 | PRCP | 5547 | 201494_at | -0.8058 | 0.0027 | |
| GSE29001 | PRCP | 5547 | 201494_at | -0.6143 | 0.0107 | |
| GSE38129 | PRCP | 5547 | 201494_at | -0.3900 | 0.0037 | |
| GSE45670 | PRCP | 5547 | 201494_at | -0.2084 | 0.2877 | |
| GSE53622 | PRCP | 5547 | 139968 | -0.5332 | 0.0000 | |
| GSE53624 | PRCP | 5547 | 139968 | -0.4841 | 0.0000 | |
| GSE63941 | PRCP | 5547 | 201494_at | -1.0209 | 0.0435 | |
| GSE77861 | PRCP | 5547 | 201494_at | -0.3783 | 0.3232 | |
| GSE97050 | PRCP | 5547 | A_23_P127964 | 0.2456 | 0.4737 | |
| SRP007169 | PRCP | 5547 | RNAseq | -0.6012 | 0.1022 | |
| SRP008496 | PRCP | 5547 | RNAseq | -0.8800 | 0.0001 | |
| SRP064894 | PRCP | 5547 | RNAseq | 0.0927 | 0.6601 | |
| SRP133303 | PRCP | 5547 | RNAseq | -0.5644 | 0.0006 | |
| SRP159526 | PRCP | 5547 | RNAseq | -0.2833 | 0.3809 | |
| SRP193095 | PRCP | 5547 | RNAseq | -0.6593 | 0.0006 | |
| SRP219564 | PRCP | 5547 | RNAseq | -0.1763 | 0.5786 | |
| TCGA | PRCP | 5547 | RNAseq | -0.0041 | 0.9454 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PRCP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRCP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRCP | 5547 | 2 | 9 | 19 | |
| GSE20123 | PRCP | 5547 | 2 | 9 | 19 | |
| GSE43470 | PRCP | 5547 | 2 | 5 | 36 | |
| GSE46452 | PRCP | 5547 | 5 | 23 | 31 | |
| GSE47630 | PRCP | 5547 | 3 | 18 | 19 | |
| GSE54993 | PRCP | 5547 | 8 | 2 | 60 | |
| GSE54994 | PRCP | 5547 | 6 | 18 | 29 | |
| GSE60625 | PRCP | 5547 | 0 | 3 | 8 | |
| GSE74703 | PRCP | 5547 | 1 | 4 | 31 | |
| GSE74704 | PRCP | 5547 | 2 | 6 | 12 | |
| TCGA | PRCP | 5547 | 18 | 36 | 42 |
Total number of gains: 49; Total number of losses: 133; Total Number of normals: 306.
Somatic mutations of PRCP:
Generating mutation plots.
Highly correlated genes for PRCP:
Showing top 20/350 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRCP | CERS3 | 0.734208 | 3 | 0 | 3 |
| PRCP | IREB2 | 0.6894 | 4 | 0 | 4 |
| PRCP | ABHD17C | 0.680329 | 3 | 0 | 3 |
| PRCP | RAB1A | 0.676999 | 3 | 0 | 3 |
| PRCP | AVEN | 0.676676 | 3 | 0 | 3 |
| PRCP | HLA-DQB1 | 0.671372 | 3 | 0 | 3 |
| PRCP | ACER3 | 0.669184 | 4 | 0 | 3 |
| PRCP | IER3IP1 | 0.661113 | 3 | 0 | 3 |
| PRCP | AMPD3 | 0.659386 | 3 | 0 | 3 |
| PRCP | GPATCH11 | 0.6579 | 3 | 0 | 3 |
| PRCP | STT3B | 0.649489 | 4 | 0 | 3 |
| PRCP | AQR | 0.646784 | 4 | 0 | 4 |
| PRCP | EMB | 0.644467 | 4 | 0 | 3 |
| PRCP | GFPT1 | 0.634696 | 4 | 0 | 3 |
| PRCP | EHD4 | 0.626759 | 3 | 0 | 3 |
| PRCP | CMA1 | 0.625718 | 3 | 0 | 3 |
| PRCP | SIAE | 0.624511 | 8 | 0 | 8 |
| PRCP | ST3GAL6 | 0.624398 | 3 | 0 | 3 |
| PRCP | ECI2 | 0.622694 | 3 | 0 | 3 |
| PRCP | CCDC90B | 0.62239 | 9 | 0 | 8 |
For details and further investigation, click here
