| Full name: ELOVL fatty acid elongase 5 | Alias Symbol: HELO1|dJ483K16.1 | ||
| Type: protein-coding gene | Cytoband: 6p12.1 | ||
| Entrez ID: 60481 | HGNC ID: HGNC:21308 | Ensembl Gene: ENSG00000012660 | OMIM ID: 611805 |
| Drug and gene relationship at DGIdb | |||
Expression of ELOVL5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELOVL5 | 60481 | 208788_at | 0.0862 | 0.9078 | |
| GSE20347 | ELOVL5 | 60481 | 208788_at | 0.8452 | 0.0029 | |
| GSE23400 | ELOVL5 | 60481 | 208788_at | 0.9930 | 0.0000 | |
| GSE26886 | ELOVL5 | 60481 | 208788_at | 0.8075 | 0.0042 | |
| GSE29001 | ELOVL5 | 60481 | 208788_at | 0.6780 | 0.0516 | |
| GSE38129 | ELOVL5 | 60481 | 208788_at | 0.7642 | 0.0017 | |
| GSE45670 | ELOVL5 | 60481 | 208788_at | 0.0470 | 0.8970 | |
| GSE53622 | ELOVL5 | 60481 | 10394 | 0.6332 | 0.0000 | |
| GSE53624 | ELOVL5 | 60481 | 10394 | 0.7585 | 0.0000 | |
| GSE63941 | ELOVL5 | 60481 | 208788_at | -0.8781 | 0.0092 | |
| GSE77861 | ELOVL5 | 60481 | 208788_at | 1.2781 | 0.0173 | |
| GSE97050 | ELOVL5 | 60481 | A_33_P3273719 | 0.5329 | 0.2426 | |
| SRP007169 | ELOVL5 | 60481 | RNAseq | 1.1979 | 0.0021 | |
| SRP008496 | ELOVL5 | 60481 | RNAseq | 0.9704 | 0.0001 | |
| SRP064894 | ELOVL5 | 60481 | RNAseq | 0.4860 | 0.0572 | |
| SRP133303 | ELOVL5 | 60481 | RNAseq | 0.9136 | 0.0000 | |
| SRP159526 | ELOVL5 | 60481 | RNAseq | 0.6330 | 0.0747 | |
| SRP193095 | ELOVL5 | 60481 | RNAseq | 0.9296 | 0.0000 | |
| SRP219564 | ELOVL5 | 60481 | RNAseq | 0.6429 | 0.0608 | |
| TCGA | ELOVL5 | 60481 | RNAseq | 0.3690 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ELOVL5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELOVL5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELOVL5 | 60481 | 7 | 2 | 21 | |
| GSE20123 | ELOVL5 | 60481 | 7 | 2 | 21 | |
| GSE43470 | ELOVL5 | 60481 | 5 | 0 | 38 | |
| GSE46452 | ELOVL5 | 60481 | 2 | 10 | 47 | |
| GSE47630 | ELOVL5 | 60481 | 7 | 5 | 28 | |
| GSE54993 | ELOVL5 | 60481 | 3 | 1 | 66 | |
| GSE54994 | ELOVL5 | 60481 | 8 | 5 | 40 | |
| GSE60625 | ELOVL5 | 60481 | 0 | 3 | 8 | |
| GSE74703 | ELOVL5 | 60481 | 5 | 0 | 31 | |
| GSE74704 | ELOVL5 | 60481 | 2 | 1 | 17 | |
| TCGA | ELOVL5 | 60481 | 21 | 13 | 62 |
Total number of gains: 67; Total number of losses: 42; Total Number of normals: 379.
Somatic mutations of ELOVL5:
Generating mutation plots.
Highly correlated genes for ELOVL5:
Showing top 20/1193 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELOVL5 | CALCRL | 0.756902 | 3 | 0 | 3 |
| ELOVL5 | INTS10 | 0.746289 | 3 | 0 | 3 |
| ELOVL5 | SLITRK6 | 0.74576 | 3 | 0 | 3 |
| ELOVL5 | CCNT1 | 0.735024 | 3 | 0 | 3 |
| ELOVL5 | DOCK5 | 0.734907 | 4 | 0 | 4 |
| ELOVL5 | RICTOR | 0.729125 | 3 | 0 | 3 |
| ELOVL5 | ERP29 | 0.713855 | 3 | 0 | 3 |
| ELOVL5 | RCN2 | 0.712644 | 9 | 0 | 9 |
| ELOVL5 | RAB34 | 0.703654 | 3 | 0 | 3 |
| ELOVL5 | CEP170 | 0.697902 | 3 | 0 | 3 |
| ELOVL5 | DMXL2 | 0.696124 | 9 | 0 | 8 |
| ELOVL5 | DHX33 | 0.695844 | 5 | 0 | 5 |
| ELOVL5 | SLC39A10 | 0.691765 | 6 | 0 | 6 |
| ELOVL5 | ST6GALNAC3 | 0.689626 | 3 | 0 | 3 |
| ELOVL5 | RRM2B | 0.684288 | 3 | 0 | 3 |
| ELOVL5 | DOK6 | 0.683349 | 4 | 0 | 3 |
| ELOVL5 | ADSL | 0.680672 | 11 | 0 | 11 |
| ELOVL5 | PPM1D | 0.677788 | 3 | 0 | 3 |
| ELOVL5 | CYTH3 | 0.677241 | 3 | 0 | 3 |
| ELOVL5 | SLC35B2 | 0.676504 | 4 | 0 | 4 |
For details and further investigation, click here
