| Full name: poly(rC) binding protein 1 | Alias Symbol: HNRPE1|hnRNP-E1|HNRPX|hnRNP-X | ||
| Type: protein-coding gene | Cytoband: 2p13.3 | ||
| Entrez ID: 5093 | HGNC ID: HGNC:8647 | Ensembl Gene: ENSG00000169564 | OMIM ID: 601209 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of PCBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCBP1 | 5093 | 208620_at | -0.1331 | 0.7695 | |
| GSE20347 | PCBP1 | 5093 | 208620_at | -0.3284 | 0.0882 | |
| GSE23400 | PCBP1 | 5093 | 208620_at | -0.2430 | 0.0002 | |
| GSE26886 | PCBP1 | 5093 | 208620_at | -0.9614 | 0.0008 | |
| GSE29001 | PCBP1 | 5093 | 208620_at | -0.7483 | 0.1086 | |
| GSE38129 | PCBP1 | 5093 | 208620_at | -0.1552 | 0.3077 | |
| GSE45670 | PCBP1 | 5093 | 208620_at | -0.2806 | 0.0099 | |
| GSE53622 | PCBP1 | 5093 | 50659 | 0.1342 | 0.0186 | |
| GSE53624 | PCBP1 | 5093 | 50659 | -0.0670 | 0.2225 | |
| GSE63941 | PCBP1 | 5093 | 208620_at | -0.2394 | 0.4373 | |
| GSE77861 | PCBP1 | 5093 | 208620_at | -0.0254 | 0.9389 | |
| GSE97050 | PCBP1 | 5093 | A_24_P103025 | 0.3321 | 0.1581 | |
| SRP007169 | PCBP1 | 5093 | RNAseq | -1.4473 | 0.0006 | |
| SRP008496 | PCBP1 | 5093 | RNAseq | -1.6976 | 0.0000 | |
| SRP064894 | PCBP1 | 5093 | RNAseq | -0.7571 | 0.0000 | |
| SRP133303 | PCBP1 | 5093 | RNAseq | -0.2245 | 0.1286 | |
| SRP159526 | PCBP1 | 5093 | RNAseq | -0.2298 | 0.2594 | |
| SRP193095 | PCBP1 | 5093 | RNAseq | -1.0694 | 0.0000 | |
| SRP219564 | PCBP1 | 5093 | RNAseq | -0.3331 | 0.2872 | |
| TCGA | PCBP1 | 5093 | RNAseq | 0.0622 | 0.1015 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by PCBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCBP1 | 5093 | 11 | 1 | 18 | |
| GSE20123 | PCBP1 | 5093 | 11 | 1 | 18 | |
| GSE43470 | PCBP1 | 5093 | 3 | 0 | 40 | |
| GSE46452 | PCBP1 | 5093 | 2 | 3 | 54 | |
| GSE47630 | PCBP1 | 5093 | 7 | 0 | 33 | |
| GSE54993 | PCBP1 | 5093 | 0 | 6 | 64 | |
| GSE54994 | PCBP1 | 5093 | 11 | 0 | 42 | |
| GSE60625 | PCBP1 | 5093 | 0 | 3 | 8 | |
| GSE74703 | PCBP1 | 5093 | 3 | 0 | 33 | |
| GSE74704 | PCBP1 | 5093 | 9 | 1 | 10 | |
| TCGA | PCBP1 | 5093 | 36 | 2 | 58 |
Total number of gains: 93; Total number of losses: 17; Total Number of normals: 378.
Somatic mutations of PCBP1:
Generating mutation plots.
Highly correlated genes for PCBP1:
Showing top 20/431 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCBP1 | ENTPD3 | 0.715961 | 3 | 0 | 3 |
| PCBP1 | SNX18 | 0.712243 | 3 | 0 | 3 |
| PCBP1 | TMEM50A | 0.694378 | 4 | 0 | 3 |
| PCBP1 | SPRED2 | 0.685986 | 3 | 0 | 3 |
| PCBP1 | RTN3 | 0.682738 | 5 | 0 | 4 |
| PCBP1 | CERS3 | 0.680055 | 3 | 0 | 3 |
| PCBP1 | SPPL2A | 0.677095 | 3 | 0 | 3 |
| PCBP1 | SLC12A6 | 0.676521 | 5 | 0 | 5 |
| PCBP1 | AQR | 0.671234 | 4 | 0 | 4 |
| PCBP1 | CTCF | 0.662845 | 3 | 0 | 3 |
| PCBP1 | AP4E1 | 0.660735 | 3 | 0 | 3 |
| PCBP1 | SLC16A14 | 0.653055 | 4 | 0 | 4 |
| PCBP1 | TAF12 | 0.65013 | 5 | 0 | 4 |
| PCBP1 | PANK1 | 0.647721 | 3 | 0 | 3 |
| PCBP1 | METAP1 | 0.647256 | 4 | 0 | 4 |
| PCBP1 | PRADC1 | 0.643263 | 4 | 0 | 4 |
| PCBP1 | STT3B | 0.640929 | 3 | 0 | 3 |
| PCBP1 | IWS1 | 0.640454 | 3 | 0 | 3 |
| PCBP1 | TMEM54 | 0.640267 | 4 | 0 | 4 |
| PCBP1 | RAB18 | 0.63947 | 4 | 0 | 3 |
For details and further investigation, click here
