| Full name: PC-esterase domain containing 1A | Alias Symbol: bA12M19.1|FLJ22376 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 64773 | HGNC ID: HGNC:16212 | Ensembl Gene: ENSG00000132635 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PCED1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCED1A | 64773 | 225505_s_at | 0.2741 | 0.3552 | |
| GSE26886 | PCED1A | 64773 | 225505_s_at | 0.5291 | 0.0066 | |
| GSE45670 | PCED1A | 64773 | 225505_s_at | 0.5201 | 0.0046 | |
| GSE53622 | PCED1A | 64773 | 108601 | 0.7536 | 0.0000 | |
| GSE53624 | PCED1A | 64773 | 31295 | -0.4936 | 0.0000 | |
| GSE63941 | PCED1A | 64773 | 225505_s_at | -0.2965 | 0.5297 | |
| GSE77861 | PCED1A | 64773 | 225505_s_at | 0.2626 | 0.1333 | |
| SRP007169 | PCED1A | 64773 | RNAseq | -0.2405 | 0.5678 | |
| SRP008496 | PCED1A | 64773 | RNAseq | 0.0500 | 0.8848 | |
| SRP064894 | PCED1A | 64773 | RNAseq | 1.2098 | 0.0000 | |
| SRP133303 | PCED1A | 64773 | RNAseq | 0.1880 | 0.3057 | |
| SRP159526 | PCED1A | 64773 | RNAseq | 0.5257 | 0.0532 | |
| SRP193095 | PCED1A | 64773 | RNAseq | 0.4110 | 0.0003 | |
| SRP219564 | PCED1A | 64773 | RNAseq | 1.0747 | 0.0293 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PCED1A expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of PCED1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCED1A | 64773 | 12 | 3 | 15 | |
| GSE20123 | PCED1A | 64773 | 13 | 3 | 14 | |
| GSE43470 | PCED1A | 64773 | 10 | 1 | 32 | |
| GSE46452 | PCED1A | 64773 | 26 | 1 | 32 | |
| GSE47630 | PCED1A | 64773 | 18 | 4 | 18 | |
| GSE54993 | PCED1A | 64773 | 2 | 14 | 54 | |
| GSE54994 | PCED1A | 64773 | 24 | 2 | 27 | |
| GSE60625 | PCED1A | 64773 | 0 | 0 | 11 | |
| GSE74703 | PCED1A | 64773 | 9 | 1 | 26 | |
| GSE74704 | PCED1A | 64773 | 8 | 1 | 11 | |
| TCGA | PCED1A | 64773 | 40 | 11 | 45 |
Total number of gains: 162; Total number of losses: 41; Total Number of normals: 285.
Somatic mutations of PCED1A:
Generating mutation plots.
Highly correlated genes for PCED1A:
Showing top 20/165 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCED1A | CXXC1 | 0.718768 | 3 | 0 | 3 |
| PCED1A | LAT | 0.691826 | 3 | 0 | 3 |
| PCED1A | CSNK1G2 | 0.664387 | 3 | 0 | 3 |
| PCED1A | STAT2 | 0.655062 | 4 | 0 | 3 |
| PCED1A | TMEM201 | 0.643998 | 3 | 0 | 3 |
| PCED1A | SRRT | 0.640916 | 5 | 0 | 5 |
| PCED1A | RAC3 | 0.638918 | 3 | 0 | 3 |
| PCED1A | CDK18 | 0.637497 | 4 | 0 | 4 |
| PCED1A | MCM8 | 0.629957 | 5 | 0 | 4 |
| PCED1A | CPXM1 | 0.629098 | 4 | 0 | 3 |
| PCED1A | NXT1 | 0.626729 | 5 | 0 | 5 |
| PCED1A | LIG3 | 0.626365 | 3 | 0 | 3 |
| PCED1A | CABIN1 | 0.624512 | 3 | 0 | 3 |
| PCED1A | GINS1 | 0.623888 | 4 | 0 | 4 |
| PCED1A | GMEB2 | 0.62297 | 5 | 0 | 5 |
| PCED1A | MRPS26 | 0.62219 | 6 | 0 | 6 |
| PCED1A | FANCL | 0.621933 | 4 | 0 | 4 |
| PCED1A | NCOA5 | 0.62116 | 4 | 0 | 4 |
| PCED1A | KNOP1 | 0.619753 | 4 | 0 | 3 |
| PCED1A | E2F1 | 0.617553 | 4 | 0 | 3 |
For details and further investigation, click here
