FAM43A

 

Full name: family with sequence similarity 43 member A Alias Symbol: FLJ90022
Type: protein-coding gene Cytoband: 3q29
Entrez ID: 131583 HGNC ID: HGNC:26888 Ensembl Gene: ENSG00000185112 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of FAM43A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FAM43A 131583 227410_at -0.2650 0.8094
GSE26886 FAM43A 131583 227410_at -0.1221 0.8022
GSE45670 FAM43A 131583 227410_at 1.0379 0.0004
GSE53622 FAM43A 131583 85399 0.0491 0.7362
GSE53624 FAM43A 131583 85399 0.2050 0.0656
GSE63941 FAM43A 131583 227410_at -0.6849 0.5836
GSE77861 FAM43A 131583 227410_at 1.4286 0.0036
GSE97050 FAM43A 131583 A_33_P3410589 0.2737 0.3660
SRP007169 FAM43A 131583 RNAseq -1.1501 0.0249
SRP008496 FAM43A 131583 RNAseq -0.4458 0.2393
SRP064894 FAM43A 131583 RNAseq 0.5868 0.0313
SRP133303 FAM43A 131583 RNAseq 0.3430 0.3417
SRP159526 FAM43A 131583 RNAseq 1.1896 0.0179
SRP193095 FAM43A 131583 RNAseq 0.7615 0.0040
SRP219564 FAM43A 131583 RNAseq 0.3734 0.4217
TCGA FAM43A 131583 RNAseq 0.2901 0.0132

Upregulated datasets: 3; Downregulated datasets: 1.  

 

Survival by FAM43A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of FAM43A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FAM43A 131583 22 0 8
GSE20123 FAM43A 131583 22 0 8
GSE43470 FAM43A 131583 24 0 19
GSE46452 FAM43A 131583 19 1 39
GSE47630 FAM43A 131583 27 2 11
GSE54993 FAM43A 131583 1 22 47
GSE54994 FAM43A 131583 41 0 12
GSE60625 FAM43A 131583 0 6 5
GSE74703 FAM43A 131583 20 0 16
GSE74704 FAM43A 131583 14 0 6
TCGA FAM43A 131583 77 0 19

Total number of gains: 267; Total number of losses: 31; Total Number of normals: 190.  

 

Somatic mutations of FAM43A:

 

Generating mutation plots.

 

Highly correlated genes for FAM43A:

 

Showing top 20/69 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FAM43ATMEM14A0.772358303
FAM43ASNRPB0.725652303
FAM43ACDC25B0.696077303
FAM43ALMF20.69477303
FAM43APSMC40.682202303
FAM43ATIMELESS0.656303303
FAM43AB4GALNT30.653726504
FAM43AHOXC100.652266303
FAM43AHDGF0.648686303
FAM43ACPSF10.648024303
FAM43ASTOX20.643817403
FAM43AWDR660.643733303
FAM43AMEST0.641654303
FAM43AFBXO410.641322303
FAM43AUBE2T0.637659303
FAM43APBK0.637571303
FAM43ANXPH40.635869303
FAM43ALCE3D0.633465403
FAM43APUS70.623529303
FAM43ACCNB20.619714403

For details and further investigation, click here