TMEM14A

 

Full name: transmembrane protein 14A Alias Symbol: PTD011|C6orf73
Type: protein-coding gene Cytoband: 6p12.2
Entrez ID: 28978 HGNC ID: HGNC:21076 Ensembl Gene: ENSG00000096092 OMIM ID: 616870
Drug and gene relationship at DGIdb

 

Expression of TMEM14A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM14A 28978 218477_at 0.1009 0.8131
GSE20347 TMEM14A 28978 218477_at 0.4512 0.0619
GSE23400 TMEM14A 28978 218477_at 0.6160 0.0000
GSE26886 TMEM14A 28978 218477_at -0.4220 0.0200
GSE29001 TMEM14A 28978 218477_at 0.5307 0.1550
GSE38129 TMEM14A 28978 218477_at 0.6462 0.0002
GSE45670 TMEM14A 28978 218477_at 0.5340 0.0383
GSE53622 TMEM14A 28978 113569 0.3032 0.0005
GSE53624 TMEM14A 28978 113569 0.4731 0.0000
GSE63941 TMEM14A 28978 218477_at 0.7679 0.2342
GSE77861 TMEM14A 28978 218477_at 0.6407 0.2672
GSE97050 TMEM14A 28978 A_23_P42080 0.3648 0.3105
SRP007169 TMEM14A 28978 RNAseq 0.6792 0.2005
SRP008496 TMEM14A 28978 RNAseq 0.6295 0.0282
SRP064894 TMEM14A 28978 RNAseq 0.2983 0.1813
SRP133303 TMEM14A 28978 RNAseq 0.4678 0.0214
SRP159526 TMEM14A 28978 RNAseq 0.2717 0.4255
SRP193095 TMEM14A 28978 RNAseq -0.3457 0.0925
SRP219564 TMEM14A 28978 RNAseq 0.4281 0.3520
TCGA TMEM14A 28978 RNAseq 0.1787 0.0513

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TMEM14A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TMEM14A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM14A 28978 7 2 21
GSE20123 TMEM14A 28978 7 2 21
GSE43470 TMEM14A 28978 5 0 38
GSE46452 TMEM14A 28978 2 10 47
GSE47630 TMEM14A 28978 7 5 28
GSE54993 TMEM14A 28978 3 1 66
GSE54994 TMEM14A 28978 8 4 41
GSE60625 TMEM14A 28978 0 3 8
GSE74703 TMEM14A 28978 5 0 31
GSE74704 TMEM14A 28978 3 1 16
TCGA TMEM14A 28978 21 12 63

Total number of gains: 68; Total number of losses: 40; Total Number of normals: 380.  

 

Somatic mutations of TMEM14A:

 

Generating mutation plots.

 

Highly correlated genes for TMEM14A:

 

Showing top 20/259 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM14AFAM43A0.772358303
TMEM14ACCL200.720283303
TMEM14AOSBPL60.643435303
TMEM14ANIPAL40.634033303
TMEM14ANT5C0.629103403
TMEM14ASFXN40.62594403
TMEM14ASPIRE20.618772303
TMEM14ATMEM440.618638404
TMEM14AUMPS0.6181808
TMEM14ARFC50.611418605
TMEM14AMARS20.606765403
TMEM14AB4GALNT30.60418503
TMEM14APCYT1A0.595826504
TMEM14AG6PD0.595031605
TMEM14AGCLC0.5912751209
TMEM14ARPA10.5856021108
TMEM14ACD1090.585186403
TMEM14AANAPC70.584221303
TMEM14AHTATIP20.581578907
TMEM14ANDUFB50.578968604

For details and further investigation, click here