| Full name: ilvB acetolactate synthase like | Alias Symbol: 209L8|AHAS|ILV2H|MGC1269|FLJ39061|MGC19535|HACL1L | ||
| Type: protein-coding gene | Cytoband: 19p13.12 | ||
| Entrez ID: 10994 | HGNC ID: HGNC:6041 | Ensembl Gene: ENSG00000105135 | OMIM ID: 605770 |
| Drug and gene relationship at DGIdb | |||
Expression of ILVBL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ILVBL | 10994 | 210624_s_at | -0.2252 | 0.4895 | |
| GSE20347 | ILVBL | 10994 | 210624_s_at | -0.2681 | 0.0589 | |
| GSE23400 | ILVBL | 10994 | 210624_s_at | -0.1699 | 0.0049 | |
| GSE26886 | ILVBL | 10994 | 210624_s_at | -0.4676 | 0.0004 | |
| GSE29001 | ILVBL | 10994 | 210624_s_at | -0.1713 | 0.4938 | |
| GSE38129 | ILVBL | 10994 | 210624_s_at | -0.1103 | 0.3879 | |
| GSE45670 | ILVBL | 10994 | 210624_s_at | 0.1965 | 0.1654 | |
| GSE53622 | ILVBL | 10994 | 49351 | -0.4756 | 0.0000 | |
| GSE53624 | ILVBL | 10994 | 49351 | -0.2049 | 0.0040 | |
| GSE63941 | ILVBL | 10994 | 210624_s_at | 0.3924 | 0.2372 | |
| GSE77861 | ILVBL | 10994 | 210624_s_at | 0.1679 | 0.5822 | |
| GSE97050 | ILVBL | 10994 | A_23_P165148 | 0.2079 | 0.4166 | |
| SRP007169 | ILVBL | 10994 | RNAseq | -1.4437 | 0.0000 | |
| SRP008496 | ILVBL | 10994 | RNAseq | -1.3254 | 0.0000 | |
| SRP064894 | ILVBL | 10994 | RNAseq | 0.2525 | 0.4292 | |
| SRP133303 | ILVBL | 10994 | RNAseq | -0.5257 | 0.0019 | |
| SRP159526 | ILVBL | 10994 | RNAseq | -0.3134 | 0.0649 | |
| SRP193095 | ILVBL | 10994 | RNAseq | -0.4765 | 0.0000 | |
| SRP219564 | ILVBL | 10994 | RNAseq | 0.1225 | 0.7336 | |
| TCGA | ILVBL | 10994 | RNAseq | -0.1026 | 0.0905 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ILVBL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ILVBL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ILVBL | 10994 | 4 | 2 | 24 | |
| GSE20123 | ILVBL | 10994 | 3 | 1 | 26 | |
| GSE43470 | ILVBL | 10994 | 2 | 6 | 35 | |
| GSE46452 | ILVBL | 10994 | 47 | 1 | 11 | |
| GSE47630 | ILVBL | 10994 | 4 | 7 | 29 | |
| GSE54993 | ILVBL | 10994 | 15 | 4 | 51 | |
| GSE54994 | ILVBL | 10994 | 6 | 13 | 34 | |
| GSE60625 | ILVBL | 10994 | 9 | 0 | 2 | |
| GSE74703 | ILVBL | 10994 | 2 | 4 | 30 | |
| GSE74704 | ILVBL | 10994 | 0 | 1 | 19 | |
| TCGA | ILVBL | 10994 | 20 | 10 | 66 |
Total number of gains: 112; Total number of losses: 49; Total Number of normals: 327.
Somatic mutations of ILVBL:
Generating mutation plots.
Highly correlated genes for ILVBL:
Showing top 20/392 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ILVBL | PREB | 0.747151 | 3 | 0 | 3 |
| ILVBL | GBF1 | 0.721763 | 3 | 0 | 3 |
| ILVBL | SERPIND1 | 0.721353 | 3 | 0 | 3 |
| ILVBL | ABCF1 | 0.714049 | 3 | 0 | 3 |
| ILVBL | GPR108 | 0.708984 | 3 | 0 | 3 |
| ILVBL | ADAM15 | 0.695293 | 3 | 0 | 3 |
| ILVBL | FAM3D | 0.694714 | 3 | 0 | 3 |
| ILVBL | ATP13A4 | 0.68791 | 3 | 0 | 3 |
| ILVBL | VCP | 0.681635 | 3 | 0 | 3 |
| ILVBL | FBXO7 | 0.674322 | 3 | 0 | 3 |
| ILVBL | RNF183 | 0.662712 | 4 | 0 | 4 |
| ILVBL | ZNF607 | 0.655133 | 3 | 0 | 3 |
| ILVBL | LRP11 | 0.653993 | 3 | 0 | 3 |
| ILVBL | PPP6R2 | 0.646583 | 3 | 0 | 3 |
| ILVBL | RFC5 | 0.64633 | 3 | 0 | 3 |
| ILVBL | DENND2C | 0.646109 | 3 | 0 | 3 |
| ILVBL | HLA-E | 0.644127 | 3 | 0 | 3 |
| ILVBL | PITHD1 | 0.642742 | 3 | 0 | 3 |
| ILVBL | KCTD15 | 0.640102 | 3 | 0 | 3 |
| ILVBL | NHSL1 | 0.639787 | 3 | 0 | 3 |
For details and further investigation, click here
