| Full name: FKBP prolyl isomerase 1B | Alias Symbol: OTK4|FKBP12.6|PPIase|FKBP9 | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 2281 | HGNC ID: HGNC:3712 | Ensembl Gene: ENSG00000119782 | OMIM ID: 600620 |
| Drug and gene relationship at DGIdb | |||
Expression of FKBP1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FKBP1B | 2281 | 206857_s_at | -0.5725 | 0.5899 | |
| GSE20347 | FKBP1B | 2281 | 206857_s_at | -0.6947 | 0.0431 | |
| GSE23400 | FKBP1B | 2281 | 206857_s_at | -0.1123 | 0.1789 | |
| GSE26886 | FKBP1B | 2281 | 206857_s_at | 0.0271 | 0.9645 | |
| GSE29001 | FKBP1B | 2281 | 206857_s_at | -0.7384 | 0.0007 | |
| GSE38129 | FKBP1B | 2281 | 206857_s_at | -0.2564 | 0.3250 | |
| GSE45670 | FKBP1B | 2281 | 206857_s_at | -0.0767 | 0.7978 | |
| GSE53622 | FKBP1B | 2281 | 25045 | -0.6082 | 0.0000 | |
| GSE53624 | FKBP1B | 2281 | 25045 | -0.4534 | 0.0000 | |
| GSE63941 | FKBP1B | 2281 | 206857_s_at | -2.5215 | 0.1020 | |
| GSE77861 | FKBP1B | 2281 | 206857_s_at | 0.3217 | 0.5849 | |
| GSE97050 | FKBP1B | 2281 | A_23_P142631 | -0.0376 | 0.9312 | |
| SRP007169 | FKBP1B | 2281 | RNAseq | -0.5102 | 0.3536 | |
| SRP008496 | FKBP1B | 2281 | RNAseq | -0.2145 | 0.5282 | |
| SRP064894 | FKBP1B | 2281 | RNAseq | -0.0354 | 0.9110 | |
| SRP133303 | FKBP1B | 2281 | RNAseq | -0.4934 | 0.0564 | |
| SRP159526 | FKBP1B | 2281 | RNAseq | 0.1936 | 0.6117 | |
| SRP193095 | FKBP1B | 2281 | RNAseq | -0.9699 | 0.0004 | |
| SRP219564 | FKBP1B | 2281 | RNAseq | -0.7637 | 0.0587 | |
| TCGA | FKBP1B | 2281 | RNAseq | -0.5856 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FKBP1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FKBP1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FKBP1B | 2281 | 10 | 2 | 18 | |
| GSE20123 | FKBP1B | 2281 | 10 | 2 | 18 | |
| GSE43470 | FKBP1B | 2281 | 2 | 1 | 40 | |
| GSE46452 | FKBP1B | 2281 | 3 | 4 | 52 | |
| GSE47630 | FKBP1B | 2281 | 8 | 0 | 32 | |
| GSE54993 | FKBP1B | 2281 | 0 | 7 | 63 | |
| GSE54994 | FKBP1B | 2281 | 10 | 0 | 43 | |
| GSE60625 | FKBP1B | 2281 | 0 | 3 | 8 | |
| GSE74703 | FKBP1B | 2281 | 2 | 0 | 34 | |
| GSE74704 | FKBP1B | 2281 | 9 | 1 | 10 | |
| TCGA | FKBP1B | 2281 | 36 | 4 | 56 |
Total number of gains: 90; Total number of losses: 24; Total Number of normals: 374.
Somatic mutations of FKBP1B:
Generating mutation plots.
Highly correlated genes for FKBP1B:
Showing top 20/39 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FKBP1B | DUOXA1 | 0.614222 | 3 | 0 | 3 |
| FKBP1B | BCR | 0.610936 | 3 | 0 | 3 |
| FKBP1B | RTF1 | 0.608748 | 3 | 0 | 3 |
| FKBP1B | NDN | 0.605425 | 4 | 0 | 3 |
| FKBP1B | EHD3 | 0.605044 | 5 | 0 | 4 |
| FKBP1B | HIPK2 | 0.603354 | 3 | 0 | 3 |
| FKBP1B | DUOX1 | 0.601897 | 4 | 0 | 4 |
| FKBP1B | SLC39A2 | 0.600103 | 4 | 0 | 3 |
| FKBP1B | PPM1D | 0.587575 | 4 | 0 | 3 |
| FKBP1B | AGFG2 | 0.58088 | 4 | 0 | 4 |
| FKBP1B | MCEE | 0.579023 | 4 | 0 | 3 |
| FKBP1B | S100A2 | 0.571793 | 3 | 0 | 3 |
| FKBP1B | YOD1 | 0.566581 | 4 | 0 | 3 |
| FKBP1B | PTN | 0.550592 | 4 | 0 | 3 |
| FKBP1B | PLLP | 0.549221 | 5 | 0 | 4 |
| FKBP1B | EPB41L4A | 0.548973 | 4 | 0 | 3 |
| FKBP1B | SCIN | 0.546873 | 5 | 0 | 3 |
| FKBP1B | MAP2K4 | 0.545683 | 6 | 0 | 3 |
| FKBP1B | MYO6 | 0.544796 | 4 | 0 | 3 |
| FKBP1B | SRPX | 0.540561 | 5 | 0 | 3 |
For details and further investigation, click here
