| Full name: guanine deaminase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q21.13 | ||
| Entrez ID: 9615 | HGNC ID: HGNC:4212 | Ensembl Gene: ENSG00000119125 | OMIM ID: 139260 |
| Drug and gene relationship at DGIdb | |||
Expression of GDA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GDA | 9615 | 224209_s_at | 1.5571 | 0.1616 | |
| GSE26886 | GDA | 9615 | 1569555_at | -0.0619 | 0.5894 | |
| GSE45670 | GDA | 9615 | 224209_s_at | 2.4529 | 0.0047 | |
| GSE53622 | GDA | 9615 | 36930 | 1.2711 | 0.0000 | |
| GSE53624 | GDA | 9615 | 62566 | 1.8156 | 0.0000 | |
| GSE63941 | GDA | 9615 | 224209_s_at | 3.4306 | 0.0967 | |
| GSE77861 | GDA | 9615 | 224209_s_at | 2.0986 | 0.0241 | |
| SRP007169 | GDA | 9615 | RNAseq | 5.5192 | 0.0000 | |
| SRP133303 | GDA | 9615 | RNAseq | 2.8168 | 0.0000 | |
| SRP193095 | GDA | 9615 | RNAseq | -0.5383 | 0.3711 | |
| SRP219564 | GDA | 9615 | RNAseq | 6.1342 | 0.0000 | |
| TCGA | GDA | 9615 | RNAseq | 0.1463 | 0.7770 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by GDA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GDA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GDA | 9615 | 6 | 11 | 13 | |
| GSE20123 | GDA | 9615 | 6 | 11 | 13 | |
| GSE43470 | GDA | 9615 | 6 | 5 | 32 | |
| GSE46452 | GDA | 9615 | 6 | 14 | 39 | |
| GSE47630 | GDA | 9615 | 1 | 18 | 21 | |
| GSE54993 | GDA | 9615 | 4 | 1 | 65 | |
| GSE54994 | GDA | 9615 | 4 | 13 | 36 | |
| GSE60625 | GDA | 9615 | 0 | 0 | 11 | |
| GSE74703 | GDA | 9615 | 5 | 4 | 27 | |
| GSE74704 | GDA | 9615 | 3 | 8 | 9 | |
| TCGA | GDA | 9615 | 19 | 27 | 50 |
Total number of gains: 60; Total number of losses: 112; Total Number of normals: 316.
Somatic mutations of GDA:
Generating mutation plots.
Highly correlated genes for GDA:
Showing top 20/201 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GDA | PKMYT1 | 0.688083 | 4 | 0 | 4 |
| GDA | PRR14 | 0.684848 | 3 | 0 | 3 |
| GDA | MRPL38 | 0.679009 | 3 | 0 | 3 |
| GDA | POLRMT | 0.662901 | 3 | 0 | 3 |
| GDA | NRM | 0.654775 | 3 | 0 | 3 |
| GDA | TTC30A | 0.649709 | 3 | 0 | 3 |
| GDA | IGF2BP3 | 0.649272 | 4 | 0 | 4 |
| GDA | THOP1 | 0.647832 | 3 | 0 | 3 |
| GDA | RNF168 | 0.646783 | 4 | 0 | 3 |
| GDA | TBC1D10B | 0.646752 | 3 | 0 | 3 |
| GDA | RAD23A | 0.642451 | 3 | 0 | 3 |
| GDA | TRAF7 | 0.641376 | 4 | 0 | 3 |
| GDA | CHTF18 | 0.6373 | 4 | 0 | 3 |
| GDA | SNRPA | 0.635449 | 3 | 0 | 3 |
| GDA | IMPDH1 | 0.634611 | 3 | 0 | 3 |
| GDA | OXLD1 | 0.634438 | 4 | 0 | 3 |
| GDA | FUT1 | 0.633381 | 3 | 0 | 3 |
| GDA | PRKCSH | 0.630494 | 3 | 0 | 3 |
| GDA | NACC1 | 0.628567 | 3 | 0 | 3 |
| GDA | TP63 | 0.62846 | 4 | 0 | 3 |
For details and further investigation, click here
