RNF168

 

Full name: ring finger protein 168 Alias Symbol: FLJ35794
Type: protein-coding gene Cytoband: 3q29
Entrez ID: 165918 HGNC ID: HGNC:26661 Ensembl Gene: ENSG00000163961 OMIM ID: 612688
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of RNF168:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RNF168 165918 226832_at 0.8919 0.0608
GSE26886 RNF168 165918 226832_at 0.5936 0.0057
GSE45670 RNF168 165918 226832_at 0.9169 0.0002
GSE53622 RNF168 165918 53230 1.0265 0.0000
GSE53624 RNF168 165918 53230 1.1204 0.0000
GSE63941 RNF168 165918 226832_at 0.4058 0.4544
GSE77861 RNF168 165918 226832_at 1.3175 0.0034
GSE97050 RNF168 165918 A_23_P416112 0.4331 0.2372
SRP007169 RNF168 165918 RNAseq 2.9876 0.0000
SRP008496 RNF168 165918 RNAseq 2.7740 0.0000
SRP064894 RNF168 165918 RNAseq 0.9179 0.0007
SRP133303 RNF168 165918 RNAseq 1.2070 0.0000
SRP159526 RNF168 165918 RNAseq 1.5532 0.0001
SRP193095 RNF168 165918 RNAseq 1.2891 0.0000
SRP219564 RNF168 165918 RNAseq 0.5315 0.1593
TCGA RNF168 165918 RNAseq 0.3301 0.0001

Upregulated datasets: 8; Downregulated datasets: 0.  

 

Survival by RNF168 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RNF168:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RNF168 165918 22 0 8
GSE20123 RNF168 165918 22 0 8
GSE43470 RNF168 165918 21 0 22
GSE46452 RNF168 165918 19 1 39
GSE47630 RNF168 165918 27 2 11
GSE54993 RNF168 165918 1 22 47
GSE54994 RNF168 165918 41 0 12
GSE60625 RNF168 165918 0 6 5
GSE74703 RNF168 165918 19 0 17
GSE74704 RNF168 165918 14 0 6
TCGA RNF168 165918 77 0 19

Total number of gains: 263; Total number of losses: 31; Total Number of normals: 194.  

 

Somatic mutations of RNF168:

 

Generating mutation plots.

 

Highly correlated genes for RNF168:

 

Showing top 20/1269 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RNF168CDCA20.747448404
RNF168ABCC50.73165707
RNF168RFC40.726898808
RNF168PRC10.71776606
RNF168FEN10.715759403
RNF168TIMELESS0.714539707
RNF168TRIM590.714024605
RNF168LMNB20.712399505
RNF168ACTL6A0.706306808
RNF168GMPS0.704825808
RNF168ARL6IP10.704105606
RNF168MND10.700735606
RNF168ST200.700216404
RNF168ECT20.699886807
RNF168CBX30.699341606
RNF168UMPS0.698362606
RNF168CENPW0.697397606
RNF168ATP13A30.695082707
RNF168SULT1A20.694587403
RNF168GINS40.694491303

For details and further investigation, click here