| Full name: transmembrane protein 88 | Alias Symbol: MGC71744|FLJ20025 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 92162 | HGNC ID: HGNC:32371 | Ensembl Gene: ENSG00000167874 | OMIM ID: 617813 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM88:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM88 | 92162 | 229452_at | -0.0515 | 0.9245 | |
| GSE26886 | TMEM88 | 92162 | 229452_at | -0.1281 | 0.4701 | |
| GSE45670 | TMEM88 | 92162 | 229452_at | -0.1840 | 0.2169 | |
| GSE53622 | TMEM88 | 92162 | 79254 | -0.7104 | 0.0000 | |
| GSE53624 | TMEM88 | 92162 | 79254 | -0.4601 | 0.0000 | |
| GSE63941 | TMEM88 | 92162 | 229452_at | 0.3716 | 0.1379 | |
| GSE77861 | TMEM88 | 92162 | 229452_at | -0.0420 | 0.7721 | |
| GSE97050 | TMEM88 | 92162 | A_23_P77859 | -0.1895 | 0.5426 | |
| SRP064894 | TMEM88 | 92162 | RNAseq | 0.3110 | 0.3998 | |
| SRP133303 | TMEM88 | 92162 | RNAseq | -0.3345 | 0.3004 | |
| SRP159526 | TMEM88 | 92162 | RNAseq | 0.0529 | 0.9036 | |
| SRP219564 | TMEM88 | 92162 | RNAseq | -0.1505 | 0.8559 | |
| TCGA | TMEM88 | 92162 | RNAseq | -0.7054 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM88 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM88:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM88 | 92162 | 4 | 2 | 24 | |
| GSE20123 | TMEM88 | 92162 | 4 | 3 | 23 | |
| GSE43470 | TMEM88 | 92162 | 1 | 6 | 36 | |
| GSE46452 | TMEM88 | 92162 | 34 | 1 | 24 | |
| GSE47630 | TMEM88 | 92162 | 7 | 1 | 32 | |
| GSE54993 | TMEM88 | 92162 | 4 | 3 | 63 | |
| GSE54994 | TMEM88 | 92162 | 5 | 8 | 40 | |
| GSE60625 | TMEM88 | 92162 | 4 | 0 | 7 | |
| GSE74703 | TMEM88 | 92162 | 1 | 3 | 32 | |
| GSE74704 | TMEM88 | 92162 | 2 | 1 | 17 | |
| TCGA | TMEM88 | 92162 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 49; Total Number of normals: 356.
Somatic mutations of TMEM88:
Generating mutation plots.
Highly correlated genes for TMEM88:
Showing top 20/165 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM88 | GIPC3 | 0.743964 | 3 | 0 | 3 |
| TMEM88 | ZNF385D | 0.7181 | 5 | 0 | 5 |
| TMEM88 | WSCD2 | 0.703181 | 3 | 0 | 3 |
| TMEM88 | L1CAM | 0.690126 | 4 | 0 | 3 |
| TMEM88 | PPP1R14A | 0.688871 | 4 | 0 | 4 |
| TMEM88 | IQUB | 0.68324 | 3 | 0 | 3 |
| TMEM88 | PDE3A | 0.673909 | 4 | 0 | 3 |
| TMEM88 | ABCC9 | 0.663463 | 4 | 0 | 4 |
| TMEM88 | CDH19 | 0.658398 | 4 | 0 | 3 |
| TMEM88 | ADCYAP1R1 | 0.65795 | 3 | 0 | 3 |
| TMEM88 | CYSLTR1 | 0.657193 | 4 | 0 | 4 |
| TMEM88 | SORCS1 | 0.656368 | 4 | 0 | 4 |
| TMEM88 | ADAL | 0.656303 | 3 | 0 | 3 |
| TMEM88 | SEMA3G | 0.652375 | 4 | 0 | 4 |
| TMEM88 | MYOT | 0.650251 | 4 | 0 | 4 |
| TMEM88 | SGCA | 0.648892 | 5 | 0 | 5 |
| TMEM88 | MBNL1-AS1 | 0.647563 | 3 | 0 | 3 |
| TMEM88 | PSD | 0.645684 | 4 | 0 | 3 |
| TMEM88 | ATP1B2 | 0.644813 | 4 | 0 | 4 |
| TMEM88 | ALDH1A2 | 0.642943 | 5 | 0 | 5 |
For details and further investigation, click here
