| Full name: von Willebrand factor A domain containing 5A | Alias Symbol: BCSC-1 | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 4013 | HGNC ID: HGNC:6658 | Ensembl Gene: ENSG00000110002 | OMIM ID: 602929 |
| Drug and gene relationship at DGIdb | |||
Expression of VWA5A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VWA5A | 4013 | 205011_at | -0.8187 | 0.1581 | |
| GSE20347 | VWA5A | 4013 | 205011_at | -0.9739 | 0.0000 | |
| GSE23400 | VWA5A | 4013 | 205011_at | -0.3799 | 0.0000 | |
| GSE26886 | VWA5A | 4013 | 210102_at | 0.0122 | 0.9783 | |
| GSE29001 | VWA5A | 4013 | 205011_at | -0.9017 | 0.0041 | |
| GSE38129 | VWA5A | 4013 | 205011_at | -0.9370 | 0.0000 | |
| GSE45670 | VWA5A | 4013 | 205011_at | -0.4882 | 0.1400 | |
| GSE53622 | VWA5A | 4013 | 64305 | -1.0236 | 0.0000 | |
| GSE53624 | VWA5A | 4013 | 64305 | -0.5527 | 0.0000 | |
| GSE63941 | VWA5A | 4013 | 210102_at | -1.9226 | 0.0981 | |
| GSE77861 | VWA5A | 4013 | 205011_at | 0.1193 | 0.8458 | |
| GSE97050 | VWA5A | 4013 | A_33_P3305105 | -0.1199 | 0.6226 | |
| SRP007169 | VWA5A | 4013 | RNAseq | -1.4583 | 0.0125 | |
| SRP008496 | VWA5A | 4013 | RNAseq | -1.2043 | 0.0009 | |
| SRP064894 | VWA5A | 4013 | RNAseq | -0.6927 | 0.0198 | |
| SRP133303 | VWA5A | 4013 | RNAseq | -1.2069 | 0.0000 | |
| SRP159526 | VWA5A | 4013 | RNAseq | -0.3895 | 0.4658 | |
| SRP193095 | VWA5A | 4013 | RNAseq | -0.8688 | 0.0008 | |
| SRP219564 | VWA5A | 4013 | RNAseq | -0.5654 | 0.1999 | |
| TCGA | VWA5A | 4013 | RNAseq | -0.5653 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by VWA5A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VWA5A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VWA5A | 4013 | 0 | 13 | 17 | |
| GSE20123 | VWA5A | 4013 | 0 | 13 | 17 | |
| GSE43470 | VWA5A | 4013 | 2 | 7 | 34 | |
| GSE46452 | VWA5A | 4013 | 3 | 26 | 30 | |
| GSE47630 | VWA5A | 4013 | 2 | 19 | 19 | |
| GSE54993 | VWA5A | 4013 | 10 | 0 | 60 | |
| GSE54994 | VWA5A | 4013 | 5 | 19 | 29 | |
| GSE60625 | VWA5A | 4013 | 0 | 3 | 8 | |
| GSE74703 | VWA5A | 4013 | 1 | 5 | 30 | |
| GSE74704 | VWA5A | 4013 | 0 | 9 | 11 | |
| TCGA | VWA5A | 4013 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of VWA5A:
Generating mutation plots.
Highly correlated genes for VWA5A:
Showing top 20/706 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VWA5A | RAB35 | 0.721271 | 3 | 0 | 3 |
| VWA5A | CLEC3B | 0.712319 | 3 | 0 | 3 |
| VWA5A | SLC9A6 | 0.710914 | 3 | 0 | 3 |
| VWA5A | TMEM150C | 0.710793 | 4 | 0 | 3 |
| VWA5A | VSTM4 | 0.703672 | 4 | 0 | 3 |
| VWA5A | DLD | 0.698146 | 3 | 0 | 3 |
| VWA5A | CCDC3 | 0.697635 | 4 | 0 | 3 |
| VWA5A | CMTM6 | 0.691738 | 3 | 0 | 3 |
| VWA5A | SACM1L | 0.68905 | 5 | 0 | 5 |
| VWA5A | PI16 | 0.688433 | 3 | 0 | 3 |
| VWA5A | FBXO8 | 0.688084 | 4 | 0 | 3 |
| VWA5A | MRAS | 0.681199 | 3 | 0 | 3 |
| VWA5A | SRR | 0.679741 | 4 | 0 | 4 |
| VWA5A | PRKACA | 0.679436 | 3 | 0 | 3 |
| VWA5A | CYP21A2 | 0.678616 | 3 | 0 | 3 |
| VWA5A | DENND5B | 0.670227 | 3 | 0 | 3 |
| VWA5A | PLAC9 | 0.669593 | 4 | 0 | 3 |
| VWA5A | ANGPTL1 | 0.667507 | 5 | 0 | 4 |
| VWA5A | APIP | 0.666899 | 4 | 0 | 3 |
| VWA5A | SMOC2 | 0.666112 | 4 | 0 | 4 |
For details and further investigation, click here
