| Full name: Fc fragment of IgG receptor Ib | Alias Symbol: CD64b | ||
| Type: protein-coding gene | Cytoband: 1p11.2 | ||
| Entrez ID: 2210 | HGNC ID: HGNC:3614 | Ensembl Gene: ENSG00000198019 | OMIM ID: 601502 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of FCGR1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FCGR1B | 2210 | 214511_x_at | 0.9951 | 0.3671 | |
| GSE20347 | FCGR1B | 2210 | 214511_x_at | 0.5174 | 0.0009 | |
| GSE23400 | FCGR1B | 2210 | 214511_x_at | 0.3477 | 0.0000 | |
| GSE26886 | FCGR1B | 2210 | 214511_x_at | 0.1591 | 0.4628 | |
| GSE29001 | FCGR1B | 2210 | 214511_x_at | 0.7405 | 0.0061 | |
| GSE38129 | FCGR1B | 2210 | 214511_x_at | 0.7955 | 0.0000 | |
| GSE45670 | FCGR1B | 2210 | 214511_x_at | 0.6284 | 0.0615 | |
| GSE63941 | FCGR1B | 2210 | 214511_x_at | 0.0350 | 0.8233 | |
| GSE77861 | FCGR1B | 2210 | 214511_x_at | 0.1635 | 0.1606 | |
| GSE97050 | FCGR1B | A_21_P0010728 | 0.7641 | 0.1783 | ||
| SRP133303 | FCGR1B | 2210 | RNAseq | 0.3049 | 0.3068 | |
| SRP159526 | FCGR1B | 2210 | RNAseq | 0.2325 | 0.6122 | |
| SRP219564 | FCGR1B | 2210 | RNAseq | 1.0328 | 0.2416 | |
| TCGA | FCGR1B | 2210 | RNAseq | -0.2799 | 0.2461 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FCGR1B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FCGR1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FCGR1B | 2210 | 1 | 6 | 23 | |
| GSE20123 | FCGR1B | 2210 | 2 | 5 | 23 | |
| GSE43470 | FCGR1B | 2210 | 2 | 3 | 38 | |
| GSE46452 | FCGR1B | 2210 | 2 | 1 | 56 | |
| GSE47630 | FCGR1B | 2210 | 11 | 3 | 26 | |
| GSE54993 | FCGR1B | 2210 | 0 | 1 | 69 | |
| GSE54994 | FCGR1B | 2210 | 12 | 0 | 41 | |
| GSE60625 | FCGR1B | 2210 | 0 | 0 | 11 | |
| GSE74703 | FCGR1B | 2210 | 1 | 3 | 32 | |
| GSE74704 | FCGR1B | 2210 | 1 | 3 | 16 | |
| TCGA | FCGR1B | 2210 | 33 | 15 | 48 |
Total number of gains: 65; Total number of losses: 40; Total Number of normals: 383.
Somatic mutations of FCGR1B:
Generating mutation plots.
Highly correlated genes for FCGR1B:
Showing top 20/299 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FCGR1B | TFEC | 0.849376 | 7 | 0 | 7 |
| FCGR1B | CD300LF | 0.737619 | 4 | 0 | 3 |
| FCGR1B | BATF2 | 0.726787 | 5 | 0 | 5 |
| FCGR1B | TYROBP | 0.724698 | 8 | 0 | 8 |
| FCGR1B | C1QB | 0.723332 | 8 | 0 | 8 |
| FCGR1B | HAPLN3 | 0.719555 | 4 | 0 | 4 |
| FCGR1B | SFMBT2 | 0.717392 | 3 | 0 | 3 |
| FCGR1B | FCER1G | 0.714862 | 9 | 0 | 8 |
| FCGR1B | SLC7A7 | 0.71329 | 10 | 0 | 8 |
| FCGR1B | ITGA4 | 0.698416 | 5 | 0 | 5 |
| FCGR1B | CCR5 | 0.698166 | 6 | 0 | 6 |
| FCGR1B | POLQ | 0.689828 | 3 | 0 | 3 |
| FCGR1B | SLAMF8 | 0.686777 | 10 | 0 | 9 |
| FCGR1B | ITGB2 | 0.686267 | 8 | 0 | 8 |
| FCGR1B | IGSF6 | 0.683922 | 8 | 0 | 7 |
| FCGR1B | SLA2 | 0.683783 | 4 | 0 | 3 |
| FCGR1B | CCR1 | 0.682749 | 10 | 0 | 8 |
| FCGR1B | TNFSF13B | 0.680879 | 6 | 0 | 6 |
| FCGR1B | GNLY | 0.672537 | 8 | 0 | 6 |
| FCGR1B | CYBB | 0.671587 | 8 | 0 | 6 |
For details and further investigation, click here
