| Full name: HLA complex P5 | Alias Symbol: D6S2650E|P5-1 | ||
| Type: non-coding RNA | Cytoband: 6p21.33 | ||
| Entrez ID: 10866 | HGNC ID: HGNC:21659 | Ensembl Gene: ENSG00000206337 | OMIM ID: 604676 |
| Drug and gene relationship at DGIdb | |||
Expression of HCP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HCP5 | 10866 | 206082_at | 1.0027 | 0.2734 | |
| GSE20347 | HCP5 | 10866 | 206082_at | 0.4400 | 0.1766 | |
| GSE23400 | HCP5 | 10866 | 206082_at | 0.6663 | 0.0000 | |
| GSE26886 | HCP5 | 10866 | 206082_at | 0.7425 | 0.0767 | |
| GSE29001 | HCP5 | 10866 | 206082_at | 1.2616 | 0.0014 | |
| GSE38129 | HCP5 | 10866 | 206082_at | 0.7291 | 0.0040 | |
| GSE45670 | HCP5 | 10866 | 206082_at | 1.2617 | 0.0054 | |
| GSE53622 | HCP5 | 10866 | 52678 | 0.8270 | 0.0000 | |
| GSE53624 | HCP5 | 10866 | 52678 | 0.8549 | 0.0000 | |
| GSE63941 | HCP5 | 10866 | 206082_at | 2.6116 | 0.0249 | |
| GSE77861 | HCP5 | 10866 | 206082_at | 0.3001 | 0.3100 | |
| SRP007169 | HCP5 | 10866 | RNAseq | 1.1464 | 0.0025 | |
| SRP008496 | HCP5 | 10866 | RNAseq | 1.0646 | 0.0011 | |
| SRP064894 | HCP5 | 10866 | RNAseq | 1.0231 | 0.0001 | |
| SRP133303 | HCP5 | 10866 | RNAseq | 0.5665 | 0.0385 | |
| SRP159526 | HCP5 | 10866 | RNAseq | 0.2832 | 0.6352 | |
| SRP193095 | HCP5 | 10866 | RNAseq | 0.5176 | 0.0115 | |
| SRP219564 | HCP5 | 10866 | RNAseq | 1.3683 | 0.0592 | |
| TCGA | HCP5 | 10866 | RNAseq | 0.4574 | 0.0002 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by HCP5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HCP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HCP5 | 10866 | 5 | 2 | 23 | |
| GSE20123 | HCP5 | 10866 | 5 | 2 | 23 | |
| GSE43470 | HCP5 | 10866 | 5 | 1 | 37 | |
| GSE46452 | HCP5 | 10866 | 1 | 10 | 48 | |
| GSE47630 | HCP5 | 10866 | 7 | 4 | 29 | |
| GSE54993 | HCP5 | 10866 | 2 | 1 | 67 | |
| GSE54994 | HCP5 | 10866 | 11 | 4 | 38 | |
| GSE60625 | HCP5 | 10866 | 0 | 1 | 10 | |
| GSE74703 | HCP5 | 10866 | 5 | 0 | 31 | |
| GSE74704 | HCP5 | 10866 | 2 | 0 | 18 | |
| TCGA | HCP5 | 10866 | 16 | 16 | 64 |
Total number of gains: 59; Total number of losses: 41; Total Number of normals: 388.
Somatic mutations of HCP5:
Generating mutation plots.
Highly correlated genes for HCP5:
Showing top 20/193 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HCP5 | TAP1 | 0.72926 | 9 | 0 | 9 |
| HCP5 | HLA-F | 0.703944 | 12 | 0 | 11 |
| HCP5 | PSMB8-AS1 | 0.68628 | 6 | 0 | 6 |
| HCP5 | HLA-B | 0.678959 | 12 | 0 | 12 |
| HCP5 | HLA-G | 0.667298 | 10 | 0 | 9 |
| HCP5 | PSMB8 | 0.664999 | 12 | 0 | 10 |
| HCP5 | HLA-A | 0.662275 | 12 | 0 | 11 |
| HCP5 | PSMB9 | 0.648235 | 12 | 0 | 11 |
| HCP5 | SLC28A3 | 0.642896 | 3 | 0 | 3 |
| HCP5 | HLA-C | 0.636282 | 12 | 0 | 10 |
| HCP5 | UBE2L6 | 0.633373 | 12 | 0 | 10 |
| HCP5 | RNF213 | 0.626631 | 4 | 0 | 4 |
| HCP5 | PARP9 | 0.616357 | 6 | 0 | 4 |
| HCP5 | EPSTI1 | 0.612528 | 6 | 0 | 5 |
| HCP5 | BTN3A2 | 0.610557 | 11 | 0 | 8 |
| HCP5 | DTX3L | 0.610241 | 6 | 0 | 5 |
| HCP5 | GBP1 | 0.607217 | 10 | 0 | 8 |
| HCP5 | DDX60 | 0.604386 | 10 | 0 | 7 |
| HCP5 | IFIH1 | 0.602567 | 8 | 0 | 6 |
| HCP5 | NLRC5 | 0.601093 | 8 | 0 | 6 |
For details and further investigation, click here
