KIF20A

 

Full name: kinesin family member 20A Alias Symbol: 
Type: protein-coding gene Cytoband: 5q31.2
Entrez ID: 10112 HGNC ID: HGNC:9787 Ensembl Gene: ENSG00000112984 OMIM ID: 605664
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of KIF20A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KIF20A 10112 218755_at 1.7272 0.0262
GSE20347 KIF20A 10112 218755_at 1.7677 0.0000
GSE23400 KIF20A 10112 218755_at 1.2419 0.0000
GSE26886 KIF20A 10112 218755_at 0.7956 0.0293
GSE29001 KIF20A 10112 218755_at 1.6760 0.0000
GSE38129 KIF20A 10112 218755_at 2.0669 0.0000
GSE45670 KIF20A 10112 218755_at 1.8561 0.0000
GSE53622 KIF20A 10112 32581 2.2811 0.0000
GSE53624 KIF20A 10112 32581 2.2155 0.0000
GSE63941 KIF20A 10112 218755_at 2.9512 0.0137
GSE77861 KIF20A 10112 218755_at 0.7871 0.0185
GSE97050 KIF20A 10112 A_23_P256956 2.3317 0.0832
SRP007169 KIF20A 10112 RNAseq 1.9922 0.0000
SRP008496 KIF20A 10112 RNAseq 1.8021 0.0000
SRP064894 KIF20A 10112 RNAseq 2.0195 0.0000
SRP133303 KIF20A 10112 RNAseq 1.9876 0.0000
SRP159526 KIF20A 10112 RNAseq 1.4999 0.0002
SRP193095 KIF20A 10112 RNAseq 0.9011 0.0000
SRP219564 KIF20A 10112 RNAseq 1.3899 0.0579
TCGA KIF20A 10112 RNAseq 1.3474 0.0000

Upregulated datasets: 15; Downregulated datasets: 0.  

 

Survival by KIF20A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KIF20A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KIF20A 10112 3 10 17
GSE20123 KIF20A 10112 4 10 16
GSE43470 KIF20A 10112 4 5 34
GSE46452 KIF20A 10112 0 27 32
GSE47630 KIF20A 10112 0 21 19
GSE54993 KIF20A 10112 9 1 60
GSE54994 KIF20A 10112 3 13 37
GSE60625 KIF20A 10112 0 0 11
GSE74703 KIF20A 10112 3 4 29
GSE74704 KIF20A 10112 3 4 13
TCGA KIF20A 10112 4 36 56

Total number of gains: 33; Total number of losses: 131; Total Number of normals: 324.  

 

Somatic mutations of KIF20A:

 

Generating mutation plots.

 

Highly correlated genes for KIF20A:

 

Showing top 20/1924 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KIF20ACENPF0.86530712012
KIF20ATPX20.86435413013
KIF20ANEK20.85346513013
KIF20ACDKN30.85160413013
KIF20ATOP2A0.85087813013
KIF20ACEP550.8491313013
KIF20AAURKA0.84718313013
KIF20AUBE2C0.84578413013
KIF20AASPM0.84300113013
KIF20ACDC200.83997912012
KIF20ABUB10.83778111011
KIF20ACDK10.8326212012
KIF20ADTL0.83243812012
KIF20ADLGAP50.83036113013
KIF20ANUF20.829454908
KIF20ACCNB20.82852812012
KIF20AHMMR0.82620513013
KIF20AKIF140.82398413012
KIF20AKIF230.82032813012
KIF20ACDCA30.81871513013

For details and further investigation, click here