| Full name: hydroxypyruvate isomerase (putative) | Alias Symbol: HT036 | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 81888 | HGNC ID: HGNC:26948 | Ensembl Gene: ENSG00000178922 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HYI:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HYI | 81888 | 223769_x_at | -0.2459 | 0.4428 | |
| GSE20347 | HYI | 81888 | 221435_x_at | -0.1567 | 0.1010 | |
| GSE23400 | HYI | 81888 | 221435_x_at | -0.1551 | 0.0009 | |
| GSE26886 | HYI | 81888 | 223769_x_at | 0.5196 | 0.0371 | |
| GSE29001 | HYI | 81888 | 221435_x_at | -0.2574 | 0.0462 | |
| GSE38129 | HYI | 81888 | 221435_x_at | -0.2627 | 0.0275 | |
| GSE45670 | HYI | 81888 | 223769_x_at | -0.4582 | 0.0033 | |
| GSE53622 | HYI | 81888 | 93958 | -0.2963 | 0.0063 | |
| GSE53624 | HYI | 81888 | 93958 | 0.0009 | 0.9932 | |
| GSE63941 | HYI | 81888 | 223769_x_at | -0.7763 | 0.1044 | |
| GSE77861 | HYI | 81888 | 223769_x_at | -0.1724 | 0.2992 | |
| GSE97050 | HYI | 81888 | A_23_P200976 | -0.3703 | 0.2272 | |
| SRP007169 | HYI | 81888 | RNAseq | -0.9702 | 0.0938 | |
| SRP064894 | HYI | 81888 | RNAseq | 0.3690 | 0.3508 | |
| SRP133303 | HYI | 81888 | RNAseq | -0.2916 | 0.2072 | |
| SRP159526 | HYI | 81888 | RNAseq | 0.6726 | 0.1894 | |
| SRP193095 | HYI | 81888 | RNAseq | 0.2660 | 0.2900 | |
| SRP219564 | HYI | 81888 | RNAseq | -0.1973 | 0.6959 | |
| TCGA | HYI | 81888 | RNAseq | -0.2471 | 0.0153 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HYI expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HYI:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HYI | 81888 | 4 | 3 | 23 | |
| GSE20123 | HYI | 81888 | 4 | 2 | 24 | |
| GSE43470 | HYI | 81888 | 7 | 2 | 34 | |
| GSE46452 | HYI | 81888 | 3 | 1 | 55 | |
| GSE47630 | HYI | 81888 | 9 | 3 | 28 | |
| GSE54993 | HYI | 81888 | 0 | 2 | 68 | |
| GSE54994 | HYI | 81888 | 13 | 2 | 38 | |
| GSE60625 | HYI | 81888 | 0 | 0 | 11 | |
| GSE74703 | HYI | 81888 | 6 | 1 | 29 | |
| GSE74704 | HYI | 81888 | 2 | 0 | 18 | |
| TCGA | HYI | 81888 | 13 | 17 | 66 |
Total number of gains: 61; Total number of losses: 33; Total Number of normals: 394.
Somatic mutations of HYI:
Generating mutation plots.
Highly correlated genes for HYI:
Showing top 20/519 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HYI | MECP2 | 0.819177 | 3 | 0 | 3 |
| HYI | SYNC | 0.688452 | 5 | 0 | 5 |
| HYI | RWDD2B | 0.671318 | 3 | 0 | 3 |
| HYI | TMOD1 | 0.661707 | 5 | 0 | 5 |
| HYI | GNAQ | 0.661688 | 3 | 0 | 3 |
| HYI | PRKACA | 0.657323 | 3 | 0 | 3 |
| HYI | SERTAD1 | 0.649122 | 3 | 0 | 3 |
| HYI | PCDH9 | 0.648662 | 6 | 0 | 5 |
| HYI | TECPR2 | 0.643079 | 4 | 0 | 4 |
| HYI | TIMP3 | 0.642926 | 5 | 0 | 5 |
| HYI | EML1 | 0.642331 | 4 | 0 | 4 |
| HYI | SYNPO | 0.641627 | 4 | 0 | 3 |
| HYI | PBX1 | 0.638796 | 4 | 0 | 3 |
| HYI | DDX42 | 0.636421 | 4 | 0 | 3 |
| HYI | ARMC9 | 0.63441 | 3 | 0 | 3 |
| HYI | AMIGO1 | 0.633015 | 3 | 0 | 3 |
| HYI | SDAD1 | 0.632588 | 3 | 0 | 3 |
| HYI | ZER1 | 0.630843 | 5 | 0 | 3 |
| HYI | BRPF3 | 0.621943 | 4 | 0 | 4 |
| HYI | ZNF540 | 0.621279 | 4 | 0 | 4 |
For details and further investigation, click here
