| Full name: interferon alpha inducible protein 27 like 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q32.12 | ||
| Entrez ID: 122509 | HGNC ID: HGNC:19754 | Ensembl Gene: ENSG00000165948 | OMIM ID: 611320 |
| Drug and gene relationship at DGIdb | |||
Expression of IFI27L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFI27L1 | 122509 | 230172_at | -0.0340 | 0.9081 | |
| GSE26886 | IFI27L1 | 122509 | 230172_at | 0.2218 | 0.3188 | |
| GSE45670 | IFI27L1 | 122509 | 230172_at | 0.1055 | 0.4113 | |
| GSE53622 | IFI27L1 | 122509 | 51823 | -0.4031 | 0.0002 | |
| GSE53624 | IFI27L1 | 122509 | 51823 | -0.5439 | 0.0000 | |
| GSE63941 | IFI27L1 | 122509 | 230172_at | -0.2897 | 0.4533 | |
| GSE77861 | IFI27L1 | 122509 | 230172_at | -0.0965 | 0.6264 | |
| GSE97050 | IFI27L1 | 122509 | A_24_P261929 | 0.0517 | 0.8691 | |
| SRP007169 | IFI27L1 | 122509 | RNAseq | -0.1777 | 0.7981 | |
| SRP064894 | IFI27L1 | 122509 | RNAseq | 1.2581 | 0.0001 | |
| SRP133303 | IFI27L1 | 122509 | RNAseq | 0.5104 | 0.0288 | |
| SRP159526 | IFI27L1 | 122509 | RNAseq | 0.1217 | 0.7578 | |
| SRP193095 | IFI27L1 | 122509 | RNAseq | -0.0075 | 0.9624 | |
| SRP219564 | IFI27L1 | 122509 | RNAseq | 0.5708 | 0.1698 | |
| TCGA | IFI27L1 | 122509 | RNAseq | 0.0656 | 0.6214 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by IFI27L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFI27L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFI27L1 | 122509 | 9 | 4 | 17 | |
| GSE20123 | IFI27L1 | 122509 | 9 | 3 | 18 | |
| GSE43470 | IFI27L1 | 122509 | 7 | 3 | 33 | |
| GSE46452 | IFI27L1 | 122509 | 16 | 3 | 40 | |
| GSE47630 | IFI27L1 | 122509 | 11 | 8 | 21 | |
| GSE54993 | IFI27L1 | 122509 | 3 | 8 | 59 | |
| GSE54994 | IFI27L1 | 122509 | 20 | 4 | 29 | |
| GSE60625 | IFI27L1 | 122509 | 0 | 2 | 9 | |
| GSE74703 | IFI27L1 | 122509 | 6 | 3 | 27 | |
| GSE74704 | IFI27L1 | 122509 | 5 | 3 | 12 | |
| TCGA | IFI27L1 | 122509 | 30 | 20 | 46 |
Total number of gains: 116; Total number of losses: 61; Total Number of normals: 311.
Somatic mutations of IFI27L1:
Generating mutation plots.
Highly correlated genes for IFI27L1:
Showing top 20/177 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFI27L1 | RNF222 | 0.737253 | 3 | 0 | 3 |
| IFI27L1 | KRT6C | 0.727375 | 3 | 0 | 3 |
| IFI27L1 | KRT83 | 0.72573 | 3 | 0 | 3 |
| IFI27L1 | UPP1 | 0.724547 | 3 | 0 | 3 |
| IFI27L1 | RNASE7 | 0.710335 | 3 | 0 | 3 |
| IFI27L1 | ZBED2 | 0.709818 | 3 | 0 | 3 |
| IFI27L1 | CNFN | 0.705852 | 3 | 0 | 3 |
| IFI27L1 | KRT5 | 0.703752 | 3 | 0 | 3 |
| IFI27L1 | NOTO | 0.703462 | 3 | 0 | 3 |
| IFI27L1 | SBSN | 0.702361 | 3 | 0 | 3 |
| IFI27L1 | DCD | 0.693956 | 3 | 0 | 3 |
| IFI27L1 | C3orf20 | 0.689138 | 4 | 0 | 4 |
| IFI27L1 | SPRR2D | 0.679561 | 3 | 0 | 3 |
| IFI27L1 | SPRR2A | 0.67701 | 3 | 0 | 3 |
| IFI27L1 | MALL | 0.675639 | 4 | 0 | 3 |
| IFI27L1 | NCCRP1 | 0.674253 | 3 | 0 | 3 |
| IFI27L1 | RAET1E | 0.673188 | 3 | 0 | 3 |
| IFI27L1 | S100A16 | 0.673131 | 4 | 0 | 3 |
| IFI27L1 | SPRR2E | 0.671416 | 3 | 0 | 3 |
| IFI27L1 | SPRR2F | 0.669238 | 3 | 0 | 3 |
For details and further investigation, click here
