| Full name: MX dynamin like GTPase 1 | Alias Symbol: IFI-78K|MxA | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 4599 | HGNC ID: HGNC:7532 | Ensembl Gene: ENSG00000157601 | OMIM ID: 147150 |
| Drug and gene relationship at DGIdb | |||
Expression of MX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MX1 | 4599 | 202086_at | -0.0571 | 0.9717 | |
| GSE20347 | MX1 | 4599 | 202086_at | 0.3646 | 0.3993 | |
| GSE23400 | MX1 | 4599 | 202086_at | 0.5056 | 0.0044 | |
| GSE26886 | MX1 | 4599 | 202086_at | 0.0286 | 0.9552 | |
| GSE29001 | MX1 | 4599 | 202086_at | 1.2757 | 0.0040 | |
| GSE38129 | MX1 | 4599 | 202086_at | 0.4164 | 0.2191 | |
| GSE45670 | MX1 | 4599 | 202086_at | 1.7062 | 0.0001 | |
| GSE53622 | MX1 | 4599 | 53708 | 0.1908 | 0.2746 | |
| GSE53624 | MX1 | 4599 | 53708 | 0.5791 | 0.0000 | |
| GSE63941 | MX1 | 4599 | 202086_at | -0.9327 | 0.4214 | |
| GSE77861 | MX1 | 4599 | 202086_at | -0.1644 | 0.7461 | |
| GSE97050 | MX1 | 4599 | A_23_P17663 | 0.1393 | 0.8335 | |
| SRP007169 | MX1 | 4599 | RNAseq | 1.3518 | 0.0149 | |
| SRP008496 | MX1 | 4599 | RNAseq | 1.0349 | 0.0181 | |
| SRP064894 | MX1 | 4599 | RNAseq | 2.0167 | 0.0000 | |
| SRP133303 | MX1 | 4599 | RNAseq | 0.4505 | 0.3041 | |
| SRP159526 | MX1 | 4599 | RNAseq | -0.7398 | 0.3420 | |
| SRP193095 | MX1 | 4599 | RNAseq | 0.9407 | 0.0001 | |
| SRP219564 | MX1 | 4599 | RNAseq | -0.0258 | 0.9700 | |
| TCGA | MX1 | 4599 | RNAseq | 0.2612 | 0.0228 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by MX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MX1 | 4599 | 2 | 8 | 20 | |
| GSE20123 | MX1 | 4599 | 2 | 8 | 20 | |
| GSE43470 | MX1 | 4599 | 0 | 13 | 30 | |
| GSE46452 | MX1 | 4599 | 1 | 21 | 37 | |
| GSE47630 | MX1 | 4599 | 6 | 17 | 17 | |
| GSE54993 | MX1 | 4599 | 8 | 1 | 61 | |
| GSE54994 | MX1 | 4599 | 3 | 8 | 42 | |
| GSE60625 | MX1 | 4599 | 0 | 0 | 11 | |
| GSE74703 | MX1 | 4599 | 0 | 10 | 26 | |
| GSE74704 | MX1 | 4599 | 1 | 4 | 15 | |
| TCGA | MX1 | 4599 | 7 | 41 | 48 |
Total number of gains: 30; Total number of losses: 131; Total Number of normals: 327.
Somatic mutations of MX1:
Generating mutation plots.
Highly correlated genes for MX1:
Showing top 20/139 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MX1 | OAS2 | 0.81287 | 11 | 0 | 11 |
| MX1 | IFIT1 | 0.779512 | 12 | 0 | 12 |
| MX1 | PARP9 | 0.767196 | 8 | 0 | 8 |
| MX1 | RSAD2 | 0.747523 | 11 | 0 | 11 |
| MX1 | RFX5 | 0.740837 | 3 | 0 | 3 |
| MX1 | IRF7 | 0.739616 | 10 | 0 | 10 |
| MX1 | CMPK2 | 0.734705 | 7 | 0 | 6 |
| MX1 | NCAPG | 0.734448 | 3 | 0 | 3 |
| MX1 | IFI44L | 0.73038 | 12 | 0 | 10 |
| MX1 | XAF1 | 0.725652 | 11 | 0 | 10 |
| MX1 | OAS3 | 0.721409 | 10 | 0 | 10 |
| MX1 | IFI44 | 0.719388 | 12 | 0 | 12 |
| MX1 | IFIH1 | 0.712204 | 10 | 0 | 9 |
| MX1 | IFI6 | 0.701157 | 11 | 0 | 10 |
| MX1 | PARP14 | 0.695853 | 7 | 0 | 6 |
| MX1 | MEA1 | 0.693461 | 3 | 0 | 3 |
| MX1 | KNTC1 | 0.69175 | 3 | 0 | 3 |
| MX1 | IFIT3 | 0.690237 | 11 | 0 | 9 |
| MX1 | IFIT5 | 0.686333 | 11 | 0 | 9 |
| MX1 | ISG15 | 0.68596 | 10 | 0 | 9 |
For details and further investigation, click here
